In vitro assessment of cytotoxicity and labeling efficiency of 99mTc-HMPAO with stromal vascular fraction of adipose tissue [0.03%]
体外评估99mTc-HMPAO标记脂肪组织间质血管部分的细胞毒性及标记效率
V K Verma,S S Beevi,A Tabassum et al.
V K Verma et al.
Introduction: Noninvasive radionuclide imaging of cells using technetium99m-hexamethylpropyleneamine oxime ((99m)Tc-HMPAO) is a potential diagnostic tool for several applications. Herein we aimed to evaluate the labeling ...
Comparing 2-[18F]fluoro-2-deoxy-D-glucose and [68Ga]gallium-citrate translocation in Arabidopsis thaliana [0.03%]
比较拟南芥中的2-[18F]氟-2脱氧-D-葡萄糖和[68Ga]镓柠檬酸盐转运置换
Amol Fatangare,Peter Gebhardt,Hanspeter Saluz et al.
Amol Fatangare et al.
2-[(18)F]fluoro-2-deoxy-D-glucose ((18)FDG) is a glucose surrogate commonly used in clinical or animal imaging but rarely in plant imaging to trace glucose metabolism. Recently, (18)FDG has been employed in plant imaging for studying photoa...
Comparative Study
Nuclear medicine and biology. 2014 Oct;41(9):737-43. DOI:10.1016/j.nucmedbio.2014.05.143 2014
The PEGylated liposomal doxorubicin improves the delivery and therapeutic efficiency of 188Re-Liposome by modulating phagocytosis in C26 murine colon carcinoma tumor model [0.03%]
聚乙二醇化脂质体制备多柔比星可调节C26小鼠结肠癌移植瘤模型的吞噬作用并提高188Re-脂质体的药效学性能
Wei-Hsin Hsu,Si-Yen Liu,Ya-Jen Chang et al.
Wei-Hsin Hsu et al.
Liposome in delivering radionuclide for cancer therapy has been expansively studied; however, liposome itself can be deliberately entrapped and destroyed by the reticuloendothelial system, causing an insufficiency of the drug delivery, whic...
In vivo studies: comparing the administration via and the impact on the biodistribution of radiopharmaceuticals [0.03%]
体内研究：放射性药物的不同给药途径及其对生物分布的影响比较
Suyene Rocha Pinto,Michelle Alvares Sarcinelle,Marta de Souza Albernaz et al.
Suyene Rocha Pinto et al.
The use of in vivo assay to determine the biodistribution and subsequent inter-comparison with human parameters has been used since the dawn of science. The use of this type of test admits the metabolic equity among animals for inter-compar...
Comparative Study
Nuclear medicine and biology. 2014 Oct;41(9):772-4. DOI:10.1016/j.nucmedbio.2014.05.141 2014
Synthesis and preclinical evaluation of 68Ga-labeled collagelin analogs for imaging and quantification of fibrosis [0.03%]
68Ga标记胶原蛋白类似物的合成与临床前评估用于纤维化成像和定量分析
Irina Velikyan,Ulrika Rosenström,Sergio Estrada et al.
Irina Velikyan et al.
Objectives: Fibrosis affecting functionality of vital organs such as liver, lung, heart, and kidney, is involved in many chronic diseases. Positron emission tomography (PET) would not only provide precise localization and...
Synthesis and biological evaluation of carbon-11 and fluorine-18 labeled tracers for in vivo visualization of PDE10A [0.03%]
用于体内可视化PDE10A的碳-11和氟-18标记示踪剂的合成及生物评价
Maarten Ooms,Sofie Celen,Michel Koole et al.
Maarten Ooms et al.
Introduction: In vivo visualization of PDE10A using PET provides a tool to evaluate the role of PDE10A in various neuropsychiatric diseases and can also be useful in the clinical evaluation of PDE10A inhibitor drug candid...
Comparison of intratumoral FDG and Cu-ATSM distributions in cancer tissue originated spheroid (CTOS) xenografts, a tumor model retaining the original tumor properties [0.03%]
比较癌症组织来源类器官肿瘤异种移植瘤（CTOS）中氟脱氧葡萄糖和铜-64-ATSM的分布情况，保留了原始肿瘤特性的一种新型肿瘤模型研究
Takako Furukawa,Qinghua Yuan,Zhao-Hui Jin et al.
Takako Furukawa et al.
Introduction: The intratumoral distributions of [(18)F]FDG and [(64)Cu]Cu-ATSM have been reported to be similar in adenocarcinomas but different in squamous cell carcinoma (SCC) in clinical studies. In the present study, ...
Comparative Study
Nuclear medicine and biology. 2014 Sep;41(8):653-9. DOI:10.1016/j.nucmedbio.2014.05.139 2014
Green radiochemistry [0.03%]
绿色放射化学
Michael Kilbourn
Michael Kilbourn
Synthesis and evaluation of 2-amino-5-(4-[(18)F]fluorophenyl)pent-4-ynoic acid ([(18)F]FPhPA): a novel (18)F-labeled amino acid for oncologic PET imaging [0.03%]
新型氟标记的氨基酸正电子发射断层成像示踪剂2-氨基-5-(4-[(18)F]氟苯基)-戊炔酸((18)F-FPhPA)的合成及其生物评价
Jenilee D Way,Monica Wang,Ingrit Hamann et al.
Jenilee D Way et al.
Introduction: (18)F-labeled amino acids are important PET radiotracers for molecular imaging of cancer. This study describes synthesis and radiopharmacological evaluation of 2-amino-5-(4-[(18)F]fluorophenyl)pent-4-ynoic a...
Radiosynthesis and ex vivo evaluation of [(11)C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors [0.03%]
单酰甘油酯酶抑制剂的放射合成和体外评价Carbon-11羰基碳酰胺和脲类化合物
Justin W Hicks,Jun Parkes,Junchao Tong et al.
Justin W Hicks et al.
Introduction: Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH) are the two primary enzymes that regulate the tone of endocannabinoid signaling. Although new PET radiotracers have been discovered for im...