Radiolabeling of HTE1PA: A new monopicolinate cyclam derivative for Cu-64 phenotypic imaging. In vitro and in vivo stability studies in mice [0.03%]
HTE1PA的新单吡啶甲酸cyclam衍生物的放射性标记：用于Cu-64表型成像。小鼠体外和体内稳定性研究
Mathieu Frindel,Nathalie Camus,Aurore Rauscher et al.
Mathieu Frindel et al.
Introduction: HTE1PA, a monopicolinate-N-alkylated cyclam-based ligand has previously demonstrated fast complexation process, high kinetic inertness and important thermodynamic and electrochemical stability with respect t...
Detection of activated platelets in a mouse model of carotid artery thrombosis with 18 F-labeled single-chain antibodies [0.03%]
一种用于检测动脉血栓小鼠模型中活化血小板的放射性配体分子
Katie Ardipradja,Shinn Dee Yeoh,Karen Alt et al.
Katie Ardipradja et al.
Introduction: Activated platelets are key players in thrombosis and inflammation. We previously generated single-chain antibodies (scFv) against ligand-induced binding sites (LIBS) on the highly abundant platelet glycopro...
Influence of free fatty acids on glucose uptake in prostate cancer cells [0.03%]
游离脂肪酸对前列腺癌细胞葡萄糖摄取的影响
Kim Francis Andersen,Vadim Divilov,Kuntalkumar Sevak et al.
Kim Francis Andersen et al.
Introduction: The study focuses on the interaction between glucose and free fatty acids (FFA) in malignant human prostate cancer cell lines by an in vitro observation of uptake of fluoro-2-deoxy-D-glucose (FDG) and acetat...
68Ga-DOTA-NGR as a novel molecular probe for APN-positive tumor imaging using MicroPET [0.03%]
68镓-DOTA-NGR作为正APN分子显像探针的初步研究
Jun Zhang,Xiaoli Lu,Nan Wan et al.
Jun Zhang et al.
Aminopeptidase N (APN) is selectively expressed on many tumors and the endothelium of tumor neovasculature, and may serve as a promising target for cancer diagnosis and therapy. Asparagine-glycine-arginine (NGR) peptides have been shown to ...
Transcriptional response of kidney tissue after 177Lu-octreotate administration in mice [0.03%]
镥-177奥曲肽给药后小鼠肾脏组织转录组反应分析
Emil Schüler,Nils Rudqvist,Toshima Z Parris et al.
Emil Schüler et al.
Introduction: The kidneys are one of the main dose limiting organs in (177)Lu-octreotate therapy of neuroendocrine tumors. Therefore, biomarkers for radiation damage would be of great importance in this type of therapy. T...
The production of radionuclides for nuclear medicine from a compact, low-energy accelerator system [0.03%]
一种紧凑型低能量加速器系统在核医学放射性同位素生产中的应用
William D Webster,Geoffrey T Parks,Dmitry Titov et al.
William D Webster et al.
Introduction: The field of nuclear medicine is reliant on radionuclides for medical imaging procedures and radioimmunotherapy (RIT). The recent shut-downs of key radionuclide producers have highlighted the fragility of th...
Comparison of two new angiogenesis PET tracers 68Ga-NODAGA-E[c(RGDyK)]2 and (64)Cu-NODAGA-E[c(RGDyK)]2; in vivo imaging studies in human xenograft tumors [0.03%]
新型血管生成PET示踪剂68Ga-NODAGA-E[c(RGDyK)]2和(64)Cu-NODAGA-E[c(RGDyK)]2的比较研究及人源性异种移植物肿瘤活体成像研究
Jytte Oxboel,Malene Brandt-Larsen,Christina Schjoeth-Eskesen et al.
Jytte Oxboel et al.
Introduction: The aim of this study was to synthesize and perform a side-by-side comparison of two new tumor-angiogenesis PET tracers (68)Ga-NODAGA-E[c(RGDyK)](2) and (64)Cu-NODAGA-E[c(RGDyK)](2) in vivo using human xenog...
Comparative Study
Nuclear medicine and biology. 2014 Mar;41(3):259-67. DOI:10.1016/j.nucmedbio.2013.12.003 2014
Quantification of GABAA receptors in the rat brain with [(123)I]Iomazenil SPECT from factor analysis-denoised images [0.03%]
基于因子分析去噪图像的纹状体外神经元模型中的多巴胺能可塑性
Stergios Tsartsalis,Marcelle Moulin-Sallanon,Noé Dumas et al.
Stergios Tsartsalis et al.
Purpose: In vivo imaging of GABAA receptors is essential for the comprehension of psychiatric disorders in which the GABAergic system is implicated. Small animal SPECT provides a modality for in vivo imaging of the GABAer...
Preparation of Ga-68-NOTA as a renal PET agent and feasibility tests in mice [0.03%]
Ga-68-NOTA的制备及其在小鼠体内的肾显像研究
Ji Youn Lee,Jae Min Jeong,Young Ju Kim et al.
Ji Youn Lee et al.
Introduction: Positron emission tomography (PET) may provide more accurate quantification of kidney function such as glomerular filtration rate (GFR) than gamma imaging. The purpose of these experiments was to prepare and...
Aptamer imaging with Cu-64 labeled AS1411: preliminary assessment in lung cancer [0.03%]
Cu-64标记的AS1411适配子在肺癌显像中的初步评价研究
Junling Li,Huaiyu Zheng,Paula J Bates et al.
Junling Li et al.
Introduction: AS1411 is a 26-base guanine-rich oligonucleotide aptamer shown binding to surface nucleolin, a protein over-expressed in multiple cancer cells, thus AS1411 labeled with a PET isotope can be explored as a pot...