Putrescine is required for the expression of eif-5a in Trichomonas vaginalis [0.03%]
putrescine对阴道毛滴虫eif-5a的表达是必需的
Bertha Isabel Carvajal-Gamez,Rossana Arroyo,Minerva Camacho-Nuez et al.
Bertha Isabel Carvajal-Gamez et al.
Recently, we found that Trichomonas vaginalis contains a eukaryotic translation initiation factor 5A (TveIF-5A) with unknown function in this parasite. eIF-5A is the only cellular protein dependent of polyamines to form a hypusine residue, ...
A role for p38 mitogen-activated protein kinase in early post-embryonic development of Schistosoma mansoni [0.03%]
p38丝裂原活化蛋白激酶在曼氏血吸虫早起胚胎后发育中的作用研究
Margarida Ressurreição,David Rollinson,Aidan M Emery et al.
Margarida Ressurreição et al.
The importance of p38 mitogen-activated protein kinase (p38 MAPK) to Schistosoma mansoni miracidium to mother-sporocyst development was investigated. Western blotting revealed that phosphorylation (activation) of p38 MAPK was low in larvae ...
The characterization of a unique Trypanosoma brucei β-hydroxybutyrate dehydrogenase [0.03%]
一种独特的巴贝斯虫β-羟基丁酸脱氢酶的表征
Tina D Shah,Meghan C Hickey,Kathryn E Capasso et al.
Tina D Shah et al.
A putative β-hydroxybutyrate dehydrogenase (βHBDH) ortholog was identified in Trypanosoma brucei, the unicellular eukaryotic parasite responsible for causing African Sleeping Sickness. The trypanosome enzyme has greater sequence similarit...
Specializations in a successful parasite: what makes the bloodstream-form African trypanosome so deadly? [0.03%]
成功寄生虫的特殊分化：是什么让血流形式非洲锥虫如此致命？
Catarina Gadelha,Jennifer M Holden,Harriet C Allison et al.
Catarina Gadelha et al.
Most trypanosomatid parasites have both arthropod and mammalian or plant hosts, and the ability to survive and complete a developmental program in each of these very different environments is essential for life cycle progression and hence b...
Genome-wide analysis of peptidase content and expression in a virulent and attenuated Babesia bovis strain pair [0.03%]
牛环形泰勒虫强毒株和弱毒株的蛋白酶内容及表达的全基因组分析
Maria Mesplet,Guy H Palmer,Monica J Pedroni et al.
Maria Mesplet et al.
Identifying virulence determinants in Apicomplexan parasites remains a major gap in knowledge for members within this phylum. We hypothesized that peptidases would segregate with virulence between a virulent parent Babesia bovis strain and ...
Differential expression of proteins in antimony-susceptible and -resistant isolates of Leishmania donovani [0.03%]
利什曼原虫抗锑敏感株和耐药株蛋白质的差异表达式研究
Neha Biyani,Alok Kumar Singh,Swati Mandal et al.
Neha Biyani et al.
Visceral Leishmaniasis (VL) is a parasitic disease caused by the protozoan parasite Leishmania donovani. Resistance to pentavalent antimonials (SbV), the mainstay therapy for leishmaniasis is now a major concern, due to emergence of drug re...
Molecular and immunological characterization of Fasciola antigens recognized by the MM3 monoclonal antibody [0.03%]
MM3单克隆抗体所识别的肝片吸虫抗原的分子与免疫学表征
L Muiño,M J Perteguer,T Gárate et al.
L Muiño et al.
Fascioliasis is a re-emerging parasitosis produced by liver flukes of the genus Fasciola. In this study we used protein fingerprinting (PMF) and MS/MS analysis to investigate the Fasciola secretory antigens that are recognized by mAb MM3. T...
Xinshe Li,Hongguang Shao,Ariel Junio et al.
Xinshe Li et al.
Strongyloides and related genera are advantageous subjects for transgenesis in parasitic nematodes, primarily by gonadal microinjection as has been used with Caenorhabditis elegans. Transgenesis has been achieved in Strongyloides stercorali...
Oxidative stress protection of Trypanosomes requires selenophosphate synthase [0.03%]
血蓝蛋白的双相氧敏感性及其在锥体虫氧化压力保护中的作用需要硒代磷酸合成酶
F C Costa,M A V Oliva,T C L de Jesus et al.
F C Costa et al.
Selenoproteins are characterized by the incorporation of at least one amino acid selenocysteine (Sec-U) encoded by in-frame UGA stop codons. These proteins, as well as the components of the Sec synthesis pathway, are present in members of t...
Tanya Hills,Anubhav Srivastava,Kodjo Ayi et al.
Tanya Hills et al.
Plasmodium falciparum malaria is the most important parasitic disease worldwide, responsible for an estimated 1 million deaths annually. Two P. falciparum genes code for putative phosphoglycerate mutases (PGMases), a widespread protein grou...