Computational investigation of mutations in PfCRT and PfDHFR proteins for Emerging Resistance of Plasmodium falciparum to Antimalarial drugs [0.03%]
计算研究恶性疟原虫PfCRT和PfDHFR蛋白突变以应对抗疟药物的耐药性问题
Sushruta Ghosh,Deepesh Joshi,Chandra Sekar et al.
Sushruta Ghosh et al.
The emergence of multidrug resistance in Plasmodium falciparum poses a serious threat to antimalarial treatment, particularly with growing resistance to artemisinin-based combination therapies (ACTs) and partner drugs like piperaquine. Muta...
MBP - Journal Scope Update [0.03%]
MBA期刊范围更新
Christian Doerig,Richard McCulloch,Patrick Skelly et al.
Christian Doerig et al.
Decoding Leishmania in Equines: A Comparative Analysis of Molecular Targets [0.03%]
马体内利什曼原虫的分子靶标的比较分析研究报告
Muhammad Adnan Sabir Mughal,Muhammad Kasib Khan,He Lan et al.
Muhammad Adnan Sabir Mughal et al.
Parasitic diseases caused by Leishmania spp. create considerable health concerns in animals, resulting in a considerable financial impact. They causes a complex infection in equines, affecting weight gain, skin, liver, and spleen. To date, ...
Pepscan and bioinformatic strategies for identification of potential B-cell epitopes for a peptide-based vaccine for tick control [0.03%]
用于蜱虫防控的肽类疫苗B细胞表位鉴定的Pepscan及生物信息学策略
Vinícius Andrade-Silva,Jéssica Waldman,Maria Aparecida Juliano et al.
Vinícius Andrade-Silva et al.
The cattle tick Rhipicephalus microplus poses a major problem to the livestock industry worldwide, with acaricides resistance presenting an increasing challenge. On other hand, vaccination has been suggested as a better strategy for tick co...
Biophysical analysis of an oligomerization-attenuated variant of the Leishmania donovani dynamin-1-like protein [0.03%]
利什曼原纤毛虫dynamin-1样蛋白寡聚化减弱变异体的生物物理分析
Ellen Wuyts,Ramasubramanian Sundaramoorthy,Lindsay Tulloch et al.
Ellen Wuyts et al.
Chemotherapy is a cornerstone in the battle against leishmaniasis, a neglected tropical disease caused by Leishmania parasites that affects millions worldwide. An alarming number of reports are describing treatment failure with currently av...
Evaluation of the efficacy of Perillyl alcohol in the treatment of Eimeria tenella infection [0.03%]
评估鼠尾草醇治疗艾美耳球虫感染的疗效研究
Qingyang Song,Yihao Yu,Shujing Wang et al.
Qingyang Song et al.
Recently, there has been an increased focus on the development of novel anti-parasitic drugs that exhibit both highly efficacy and low toxicity due to growing concerns associated with the widespread use of such drugs. Natural products have ...
Molecular detection and population genetic diversity analysis of Theileria ovis in partial regions of Xinjiang, China [0.03%]
中国新疆部分地区羊胎生艾美耳球虫分子检测及群体遗传多样性分析
Na Zhou,Meiling Wang,Xueqing Zhao et al.
Na Zhou et al.
Ovine theileriosis is a disease caused by the genus Theileria (e.g., T. ovis, T. lestoquardi), preventing the sheep farming industry from developing, particularly in regions reliant on sheep for milk, meat, and associated economic benefits....
Characterization and Immunogenicity Analysis of Glutathi- one S-transferase from Otodectes cynotis [0.03%]
耳痒螨谷胱甘肽转移酶的纯化鉴定及免疫学分析
Hongbo Wang,Meilin Tan,Yinbo Gui et al.
Hongbo Wang et al.
Otodectes cynotis (ear mite), the primary etiological agent of feline otitis externa, represents a significant veterinary concern due to its high prevalence and treatment challenges. Glutathione S-transferase (GST), a detoxifying and immuno...
Identification and initial characterisation of Trypanosoma Cox17 copper metallochaperone [0.03%]
识别人类锥虫中的线粒体铜离子蛋白Cox17及其初步性质研究
Murtala Bindawa Isah,Mwenya Chitembusha Kwangu,J P Dean Goldring et al.
Murtala Bindawa Isah et al.
Copper plays an essential role in organisms as a catalytic co-factor for key enzymes like cytochrome c oxidase. Copper importation, distribution and secretion is carried out by copper transport and copper-binding proteins known as copper ch...
Calcium/calmodulin-dependent protein kinase II in Schistosoma: Relation to praziquantel action and resistance [0.03%]
钙/钙调素依赖性蛋白激酶II在血吸虫体内：与吡喹酮作用及抗药性的关系
Iman F Abou-El-Naga
Iman F Abou-El-Naga
Calcium/calmodulin-dependent protein kinase II (CaMKII) performs diverse essential functions through integrating a range of calcium signals. In Schistosoma, two Calmodulin (CaM) genes are characterized. CaMKII exhibits distinct expression p...