Deleting ku80 improves the efficiency of targeted gene editing in Neospora caninum [0.03%]
删除ku80可提高新孢子虫基因组定点编辑的效率
Kaijian Wu,Xingju Song,Yayun Wu et al.
Kaijian Wu et al.
CRISPR/Cas9 technology has been widely used for gene editing in organisms. Gene deletion of the ku80/ku70 complex can improve the efficiency of gene replacement in Arabidopsis thaliana, Cryptococcus neoformans, and Toxoplasma gondii, which ...
Stress-responsive AMP Kinase like protein regulates encystation of Entamoeba invadens [0.03%]
应激响应型AMP激酶-like蛋白调控Entamoeba invadens的孢囊化过程
Piyali Goswami,Sintu Kumar Samanta,Tarun Agarwal et al.
Piyali Goswami et al.
Starvation is always accompanied by an increase in the ratio of AMP/ATP followed by activation of AMPK. It is one of the sensors for cellular energy status and is highly conserved across various species. Its role in the stage differentiatio...
Inorganic phosphate transporter in Giardia duodenalis and its possible role in ATP synthesis [0.03%]
蓝氏贾第鞭毛虫的无机磷酸盐转运蛋白及其在ATP合成中的可能作用
Ayra Diandra Carvalho-de-Araújo,Luiz Fernando Carvalho-Kelly,Claudia F Dick et al.
Ayra Diandra Carvalho-de-Araújo et al.
Giardia duodenalis is a flagellated protozoan that inhabits vertebrate host intestines, causing the disease known as giardiasis. Similar to other parasites, G. duodenalis must take advantage of environmental resources to survive, such as in...
Schistosomiasis related circulating cell-free DNA: A useful biomarker in diagnostics [0.03%]
与血吸虫病相关的循环细胞游离DNA：诊断中有用的生物标志物
Hanif Ullah,Safia Arbab,Ka Li et al.
Hanif Ullah et al.
Schistosoma is a genus of trematodes causing schistosomiasis, a major neglected tropical disease infecting more than 240 million people and with 700 million people at the risk of infection in the tropical and subtropical regions of the worl...
Increased iron uptake in the bladder wall of racemose cysts of Taenia solium [0.03%]
溶组织内阿米巴包囊膀胱壁铁吸收增加
Miguel A Orrego,Carlos M Vasquez,Kayla Togneri et al.
Miguel A Orrego et al.
Racemose neurocysticercosis is an aggressive infection caused by the aberrant expansion and proliferation of the bladder wall of the Taenia solium cyst within the subarachnoid spaces of the human brain. The parasite develops and proliferate...
Anisakis spp, DNA detection in paraffin-embedded tissue biopsies recovered from patients with gastritis using real-time PCR in Bushehr, Persian Gulf, Iran [0.03%]
伊朗波斯湾布什尔地区胃炎患者石蜡包埋组织活检中安氏属线虫的DNA实时定量PCR检测
Mohsen Najjari,Seyed Mahmoud Sadjjadi,Hossein Khodadadi et al.
Mohsen Najjari et al.
Anisakiasis is a zoonotic fish-born parasitic disease caused by anisakid nematodes. Paraffin-embedded blocks containing biopsy samples taken from patients suffering gastritis with unknown causes were investigated by real-time PCR, in the Bu...
Antiamoebic properties of salicylic acid-based deep eutectic solvents for the development of contact lens disinfecting solutions against Acanthamoeba [0.03%]
水杨酸基深共晶溶剂的抗阿米巴特性及其开发对抗Acanthamoeba的隐形眼镜消毒液的研究
Ruqaiyyah Siddiqui,Zinb Makhlouf,Noor Akbar et al.
Ruqaiyyah Siddiqui et al.
Acanthamoeba castellanii is a protist pathogen that can cause sight-threatening keratitis and a fatal infection of the central nervous system, known as granulomatous amoebic encephalitis. In this study, effects of five malonic acid and sali...
Evaluation of nanoparticles with 5-fluorouracil and chloroquine on Acanthamoeba castellanii activity [0.03%]
评估纳米颗粒中5-氟尿嘧啶和氯喹对卡氏棘阿米巴活性的影响
Balsam Qubais Saeed,Mutasem Rawas Qalaji,Noor Akbar et al.
Balsam Qubais Saeed et al.
Acanthamoeba is opportunistic pathogens that cause vision-threatening Acanthamoeba keratitis (AK). Previous studies proposed the use of chloroquine (CQ) and 5-fluorouracil (5FU) as anti-Acanthamoeba agents. The objective of this study was t...
The 'nuclear option' revisited: Confirmation of Ss-daf-12 function and therapeutic potential in Strongyloides stercoralis and other parasitic nematode infections [0.03%]
“核选项”再版：Ss-daf-12功能的确认及其在钩口属线虫感染（如丝虫症）治疗中的潜力
James B Lok,Steven A Kliewer,David J Mangelsdorf
James B Lok
Mechanisms governing morphogenesis and development of infectious third-stage larvae (L3i) of parasitic nematodes have been likened to those regulating dauer development in Caenorhabditis elegans. Dauer regulatory signal transduction compris...
Using newly optimized genetic tools to probe Strongyloides sensory behaviors [0.03%]
利用新型优化的遗传工具探究 Strongyloides 感觉行为
Patricia Mendez,Breanna Walsh,Elissa A Hallem
Patricia Mendez
The oft-neglected human-parasitic threadworm, Strongyloides stercoralis, infects roughly eight percent of the global population, placing disproportionate medical and economic burden upon marginalized communities. While current chemotherapie...