RNA editing catalytic complexes edit multiple mRNA sites non-processively in Trypanosoma brucei [0.03%]
布氏锥虫中的rna编辑催化复合体非过程化地编辑多个mRNA位点
Jason Carnes,Suzanne M McDermott,Kenneth Stuart
Jason Carnes
RNA editing generates mature mitochondrial mRNAs in T. brucei by extensive uridine insertion and deletion at numerous editing sites (ESs) as specified by guide RNAs (gRNAs). The editing is performed by three RNA Editing Catalytic Complexes ...
Eimeria granulosa causes spots visible through the serous membrane of small intestine in sheep [0.03%]
艾美尔球虫导致羊小肠浆膜上出现斑点
Yuanyuan Chen,Jing Liu,Xiaolei Liu et al.
Yuanyuan Chen et al.
Coccidiosis, also known as Eimeriosis, is a highly prevalent parasitic disease affecting sheep in nearly all sheep-rearing nations across the globe. Currently, there is a scarcity of literature documenting the specific lesions in sheep resu...
Model nematodes as a practical innovation to promote high throughput screening of natural products for anthelmintics discovery in South Asia: Current challenges, proposed practical and conceptual solutions [0.03%]
模式线虫作为实用创新促进南亚高通量筛选天然产物发现抗蠕虫药物:当前挑战,以及实用和概念性解决方案的建议
Muntasir Kamal,Suprabhat Mukherjee,Bishnu Joshi et al.
Muntasir Kamal et al.
With the increasing prevalence of anthelmintic resistance in animals recorded globally, and the threat of resistance in human helminths, the need for novel anthelmintic drugs is greater than ever. Most research aimed at discovering novel an...
Role of autophagy in stress and drug-responsive cell death in Entamoeba histolytica and its cross-talk with apoptosis-inducing factor [0.03%]
溶组织内阿米巴应激与药物诱导的细胞死亡过程中自噬的作用及其与凋亡诱导因子的交叉谈话
Anwesha Bandyopadhyay,Sudip Kumar Ghosh
Anwesha Bandyopadhyay
Cell death in unicellular protozoan parasite Entamoeba histolytica is not yet reported though it displays several features of autophagic cell death. Autophagic cell death was reported to take place in ancient protozoans under several stress...
Identification and validation of reference genes of circulating microRNAs for use as control in gestational toxoplasmosis [0.03%]
鉴定并验证循环中用于妊娠弓形虫病参考基因的微小核糖核酸
Ingrid de Siqueira Pereira,Allecineia Bispo da Cruz,Marta Marques Maia et al.
Ingrid de Siqueira Pereira et al.
Toxoplasmosis causes serious harm to the fetus, as tachyzoite dissemination, during pregnancy in women developing the primo-infection. The microRNAs (miRNAs) are small non-coding RNAs, which have regulatory roles in cells by silencing messe...
Characterization of the major surface glycoconjugates of Trypanosoma theileri [0.03%]
_TRYPANOSOMA THEILERI 主要表面糖共价化合物的特征试验报告摘要_
Rupa Nagar,Isobel Hambleton,Michele Tinti et al.
Rupa Nagar et al.
Trypanosoma theileri maintains a long-term extracellular infection with a low parasitaemia in bovids. The surface of this parasite is predicted to be decorated with several surface molecules including membrane surface proteases (MSPs), tran...
Characterisation of TcFUT1, a mitochondrial fucosyltransferase from Trypanosoma cruzi [0.03%]
宿主寄生虫相互作用及分子对策摘要集-Cds02-03克罗恩病中的微生物-免疫相互作用:来自双胞胎研究的见解
Jose Carlos Paredes Franco,Maria Lucia Sampaio Guther,Marta L Lima et al.
Jose Carlos Paredes Franco et al.
Previous work has shown that the TbFUT1 and LmjFUT1 genes encode essential fucosyltransferases located inside the single mitochondria of the protozoan parasites Trypanosoma brucei and Leishmania major, respectively. However, nothing was kno...
Does hydrogen peroxide contribute to the immunity against Malaria induced by whole attenuated plasmodial sporozoites? [0.03%]
过氧化氢对完整减毒虫孢子体诱导的疟疾免疫有贡献吗?
Bruno Douradinha
Bruno Douradinha
Plasmodium sporozoites can block apoptotic pathways within host hepatocytes, ensuring the survival of the parasite. However, attenuated plasmodial sporozoites are unable to prevent apoptosis, which provides many parasite antigens to immune ...
Novel anti-Acanthamoebic properties of raloxifene sulfonate/sulfamate derivatives [0.03%]
新型抗阿米巴原虫类风湿素磺酸/磺酰胺衍生物的活性作用
Ruqaiyyah Siddiqui,Mohammed I El-Gamal,Sreedevi Sajeev et al.
Ruqaiyyah Siddiqui et al.
Acanthamoeba are known to cause a vision threatening eye infection typically due to contact lens wear, and an infection of the central nervous system. The ability of these amoebae to switch phenotypes, from an active trophozoite to a resist...
Amino acid usage and protein expression levels in the flatworm Schistosoma mansoni [0.03%]
曼氏血吸虫中氨基酸使用和蛋白质表达水平的研究
Guillermo Lamolle,Andrés Iriarte,Diego Simón et al.
Guillermo Lamolle et al.
Schistosoma mansoni is a parasitic flatworm that causes a human disease called schistosomiasis, or bilharzia. At the genomic level, S. mansoni is AT-rich, but has some compositional heterogeneity. Indeed, some regions of its genome are GC-r...