Sonodynamic therapy: transforming sound into light for hard-to-treat tumours [0.03%]
声动力疗法：将声波转化为光线治疗难治性肿瘤
Paul Cressey,Shazwan Bin Abd Shukor,Maya Thanou
Paul Cressey
Sonodynamic therapy (SDT) is an emerging therapeutic modality against hard-to-treat tumours. It involves the use of ultrasound (US) to excite sono-sensitive moieties to produce reactive oxygen species (ROS), which induce tumour cell death. ...
Egbe Vydaline Agbor Otu,Sergei Rozhkov,German Sosa et al.
Egbe Vydaline Agbor Otu et al.
Targeted drug delivery significantly enhances therapeutic efficacy across various diseases, particularly in cancer treatments, where conventional approaches such as chemotherapy and radiotherapy often cause severe side effects. In this cont...
Recent advances in intelligent oxygen delivery systems for tissue regeneration [0.03%]
用于组织再生的智能供氧系统最新研究进展
Xuehui Rui,Yiyang Jia,Ruochen Qiao et al.
Xuehui Rui et al.
Oxygen plays a critical regulatory role in tissue repair and regeneration. However, in the microenvironment of tissues with vascular damage, hypoxia is commonly present. This not only suppresses cell proliferation and differentiation but al...
Innovative engineering approaches to model host-microbiome interactions in vitro [0.03%]
创新工程方法在体外建模宿主-微生物组相互作用
Karen M Mancera Azamar,Samanvitha Deepthi Sudi,Zahra Mohammadalizadeh et al.
Karen M Mancera Azamar et al.
The human microbiome plays a critical role in health and disease. Disruptions in microbiota composition or function have been implicated not only as markers but also as drivers of diverse pathologies, creating opportunities for targeted mic...
Junru Li,Yongming Han,Na Chen et al.
Junru Li et al.
DNA exhibits remarkable versatility, which is attributed to its inherent molecular recognition capabilities, programmable sequences, and excellent biocompatibility. Among its various topological forms, branched DNA (bDNA), including Y-shape...
Chunfa Chen,Xiaoyu Xia,Cheng Tian et al.
Chunfa Chen et al.
DNA nanotechnology, a cutting-edge field that constructs sophisticated DNA-based nanostructures by harnessing the unparalleled programmability of DNA, has evolved into a powerful tool for applications in therapy, biosensing, logic computati...
Engineering in vivo behavior of DNA nanostructures toward organ-targeted drug delivery [0.03%]
工程在体内DNA纳米结构的行为定向器官药物输送
Jihoon Won,Seunghye Cho,Kyoung-Ran Kim et al.
Jihoon Won et al.
DNA nanostructures have emerged as programmable and biocompatible platforms for drug delivery, offering precise control over size, shape, and surface properties. Recent advances have demonstrated their potential for organ-targeted delivery ...
Drug delivery, development, and technological aspects for peripheral drug eluting stents [0.03%]
外周药物洗脱支架的递送、开发和技术方面的问题
Sarika A Jadhav,Ankur J Raval,Vandana B Patravale
Sarika A Jadhav
Drug-eluting stents are the standard therapy for arterial occlusions, particularly in peripheral arterial disease, owing to their efficacy in mitigating in-stent restenosis, maintaining favorable biocompatibility, and improving patient comp...
Aptamer-based targeted drug delivery and disease therapy in preclinical and clinical applications [0.03%]
基于适配体的靶向药物递送和疾病治疗在临床前和临床应用中的研究进展
Weihong Yang,Chunyan Ran,Xinran Lian et al.
Weihong Yang et al.
The advent of precision medicine has created an urgent need for advanced drug-targeting strategies and refined drug delivery systems. Aptamers, characterized by their exceptional affinity and specificity, low molecular weight, negligible im...
Multivalent engineering of bio interfaces with DNA-based nanomaterials [0.03%]
基于DNA的纳米材料在生物界面的多功能构建工程学研究进展
Shujie Li,Yameng Lou,Maartje M C Bastings
Shujie Li
In biology, function rarely depends on a single binding event. Whether it's cell signaling, immune recognition, or adhesion, most processes rely on a critical density of interactions that occur simultaneously and in close proximity. This mu...