Qi Tony Zhou,Eric J Munson
Qi Tony Zhou
The role of microneedle arrays in drug delivery and patient monitoring to prevent diabetes induced fibrosis [0.03%]
微针阵列在药物输送和患者监测中的作用，以防止糖尿病引起的纤维化
Emma McAlister,Melissa Kirkby,Juan Domínguez-Robles et al.
Emma McAlister et al.
Diabetes affects approximately 450 million adults globally. If not effectively managed, chronic hyperglycaemia causes tissue damage that can develop into fibrosis. Fibrosis leads to end-organ complications, failure of organ systems occurs, ...
Advances on colorectal cancer 3D models: The needed translational technology for nanomedicine screening [0.03%]
结直肠癌三维模型的研究进展：纳米药物筛选所需的转化技术
Flávia Castro,Catarina Leite Pereira,Maria Helena Macedo et al.
Flávia Castro et al.
Colorectal cancer (CRC) is a heterogeneous and molecularly complex disease, associated with high mortality worldwide, exposing the urgent need for novel therapeutic approaches. Their development and translation to the clinic have been hampe...
Antimicrobial peptides towards clinical application: Delivery and formulation [0.03%]
抗菌肽的临床应用：输送及配方设计
Cheng Wang,Tingting Hong,Pengfei Cui et al.
Cheng Wang et al.
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat the multidrug resistant microbes. There are however technical hurdles towards the clinical applications, largely due to the inherent limitations of pep...
Can microorganisms develop resistance against light based anti-infective agents? [0.03%]
微生物会对抗光杀菌剂产生抗性吗？
Sanjay Marasini,Leon G Leanse,Tianhong Dai
Sanjay Marasini
Recently, there have been increasing numbers of publications illustrating the potential of light-based antimicrobial therapies to combat antimicrobial resistance. Several modalities, in particular, which have proven antimicrobial efficacy a...
Recent applications of electrical, centrifugal, and pressurised emerging technologies for fibrous structure engineering in drug delivery, regenerative medicine and theranostics [0.03%]
近年来用于药物输送、再生医学和治疗诊断学的纤维结构工程中所采用的电纺、离心和加压新兴技术的最新应用
Prina Mehta,Manoochehr Rasekh,Mohammed Patel et al.
Prina Mehta et al.
Advancements in technology and material development in recent years has led to significant breakthroughs in the remit of fiber engineering. Conventional methods such as wet spinning, melt spinning, phase separation and template synthesis ha...
Role of extracellular vesicles in liver diseases and their therapeutic potential [0.03%]
细胞外囊泡在肝病中的作用及其治疗潜力
Enis Kostallari,Shantha Valainathan,Louise Biquard et al.
Enis Kostallari et al.
More than eight hundred million people worldwide have chronic liver disease, with two million deaths per year. Recurring liver injury results in fibrogenesis, progressing towards cirrhosis, for which there doesn't exists any cure except liv...
Implications and pitfalls for cancer diagnostics exploiting extracellular vesicles [0.03%]
利用细胞外囊泡进行癌症诊断的潜在影响和陷阱
Ana Špilak,Andreas Brachner,Ulrike Kegler et al.
Ana Špilak et al.
Early detection of cancer in order to facilitate timely therapeutic interventions is an unsolved problem in today's clinical diagnostics. Tumors are detected so far mostly after pathological symptoms have emerged (usually already in progres...
Understanding the interactions between inorganic-based nanomaterials and biological membranes [0.03%]
理解无机纳米材料与生物膜的相互作用
Yiyuan Kang,Jia Liu,Yanping Jiang et al.
Yiyuan Kang et al.
The interactions between inorganic-based nanomaterials (NMs) and biological membranes are among the most important phenomena for developing NM-based therapeutics and resolving nanotoxicology. Herein, we introduce the structural and function...
Leon Jia Wei Tang,Ayshath Zaseela,Clarissa Chin Min Toh et al.
Leon Jia Wei Tang et al.
Based on our exponentially increasing knowledge of stromal heterogeneity from advances in single-cell technologies, the notion that stromal cell types exist as a spectrum of unique subpopulations that have specific functions and spatial dis...