Subspace Analysis Identifies Low-Dimensional Interactions between Cortical and Subcortical Brain Regions in Social Reward Computation [0.03%]
子空间分析识别参与社会奖励计算的皮层和皮下层脑区之间的低维相互作用
Hirokazu Tanaka,Masaki Isoda,Atsushi Noritake
Hirokazu Tanaka
Animals living in social environments evaluate rewards given to themselves and others. We previously showed that single-unit activities in cortical (the medial prefrontal cortex, MPFC) and subcortical (the dopaminergic midbrain nuclei, DA, ...
Low-speed uphill exercise increases lactate and brain-derived neurotrophic factor in brain regions for memory and learning [0.03%]
低速上坡运动可增加记忆和学习脑区的乳酸和脑源性神经营养因子水平
Masaki Takimoto,Taku Hamada
Masaki Takimoto
We investigated the acute effects of low-speed uphill exercise on lactate levels and brain-derived neurotrophic factor (BDNF) expression in the cortex and hippocampus. Male Sprague Dawley rats were divided into control, flat exercise (flat-...
Repetitive transcranial magnetic stimulation frequency influences the hemodynamic responses in patients with disorders of consciousness [0.03%]
经颅磁刺激频率影响意识障碍患者的血流动力学反应
Hao Peng,Qianqian Ge,Tianshuai Xu et al.
Hao Peng et al.
Repetitive transcranial magnetic stimulation (rTMS) emerges as a promising non-invasive neuromodulation technique for the treatment of patients with disorders of consciousness (DOC). The selection of rTMS parameters significantly influences...
Wajd Amly,Chih-Yang Chen,Hirotaka Onoe et al.
Wajd Amly et al.
Various oculomotor tasks have been used to study eye movements, cognitive control, attention, and neurological disorders. Typically, analysis focuses on successful trials, where the saccade lands very close to the intended target, in both h...
Positive allosteric modulator of GLT-1 reduces methamphetamine hyperlocomotion, sensitization and conditioned place preference in mice [0.03%]
GLT-1 正向别构调节剂可减少小鼠安非他明的多动、过敏及偏好行为
Prateek Mokkarala,Sonita Wiah,Ellen M Unterwald et al.
Prateek Mokkarala et al.
NA-014 is a positive allosteric modulator (PAM) of glutamate transporter subtype 1 (GLT-1) that increases glutamate reuptake. Since enhanced glutamate transmission facilitates methamphetamine (METH) hyperlocomotion, behavioral sensitization...
In vivo recording from calcitonin receptor-expressing neurons in the medial preoptic area during affiliative social behaviors [0.03%]
下丘脑前侧视前区表达降钙素基因相关肽神经元在社会行为中的活体记录研究
Kansai Fukumitsu,Chihiro Yoshihara,Arthur J Huang et al.
Kansai Fukumitsu et al.
Social animals, including mice, are motivated to seek social contact and avoid being alone due to the benefit of the group living in survival and reproductive values. We have previously reported that pup exposure and co-housing with adult f...
The potential mechanism maintaining transactive response DNA binding protein 43 kDa in the mouse stroke model [0.03%]
关于 Tau 蛋白在脑卒中作用机制的理论小论文
Yuting Bian,Yusuke Fukui,Ricardo Satoshi Ota-Elliott et al.
Yuting Bian et al.
The disruption of transactive response DNA binding protein 43 kDa (TDP-43) shuttling leads to the depletion of nuclear localization and the cytoplasmic accumulation of TDP-43. We aimed to evaluate the mechanism underlying the behavior of TD...
Premovement neuronal activity in the primary motor cortex is associated with the initiation of ipsilateral hand movements in monkeys [0.03%]
猴初级运动皮质的细胞活动与对侧上肢运动的启动有关
Yoshihisa Nakayama,Osamu Yokoyama,Eiji Hoshi et al.
Yoshihisa Nakayama et al.
The primary motor cortex (M1) is believed to be a cortical center for the execution of limb movements. Although M1 neurons mainly project to the spinal cord on the contralateral side, some M1 neurons project to the ipsilateral side via the ...
Loss of neuronal activity facilitates surface accumulation of p75NTR and cell death in avian cochlear nucleus [0.03%]
听神经元活性丧失可促进禽类耳蜗神经元p75NTR向细胞膜聚集及细胞死亡发生
Ryosuke Sato,Ryota Adachi,Norihiko Yokoi et al.
Ryosuke Sato et al.
Sensorineural hearing loss causes cell death in central auditory neurons, but molecular mechanisms of triggering this process are not fully understood. We report here that loss of afferent activity promotes cell death by facilitating proBDN...
Neuroanatomical distribution of endogenous huntingtin and its immunohistochemical relationships with STB/HAP1 in the adult mouse brain and spinal cord [0.03%]
内源性亨廷顿蛋白在成年小鼠脑和脊髓中的神经解剖分布及其与STB / HAP1的免疫组化关系
Md Nabiul Islam,Maruyama Mizuki,Mir Rubayet Jahan et al.
Md Nabiul Islam et al.
Huntingtin-associated protein 1 (HAP1) is an essential constituent of the stigmoid body (STB) and is known as a neuroprotective interactor with causal agents for several neurodegenerative disorders, including huntingtin (HTT) in Huntington'...