Fibril-seeded animal models of synucleinopathies: pathological mechanisms, disease modeling, and therapeutic implications [0.03%]
α-突触核蛋白病动物模型的病理机制、疾病建模和治疗意义
Norihito Uemura
Norihito Uemura
Accumulating evidence suggests that prion-like spread of misfolded α-Synuclein (αSyn) underlies the pathological progression of Lewy body diseases (LBD). Animal models injected with αSyn preformed fibrils (PFFs) have provided strong evid...
Microglial Colonization Routes and Their Impacts on Cellular Diversity [0.03%]
小胶质细胞的定植途径及其对细胞多样性的影响
Yuki Hattori
Yuki Hattori
Microglia are the resident immune cells of the central nervous system. Unlike other glial cells-such as astrocytes and oligodendrocytes-which originate from neural stem cells alongside neurons, microglia derive from erythromyeloid progenito...
Ryota Kobayashi,Ken Nakae
Ryota Kobayashi
A systematic study of changes in monoamine neurotransmitters in the rat brain following acute administration of alpha-methyltryptamine (AMT), 5-methoxy-alpha-methyltryptamine (5-MeO-AMT) and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT) [0.03%]
α-甲基色胺（AMT）、5-甲氧基-α-甲基色胺（5- MeO-AMT）和5-甲氧基-N，N-二异丙基色胺（5- MeO-DiPT）急性给药后大鼠脑内单胺类神经递质变化的系统研究
Kaixi Li,Nan Li,Yuanyuan Chen et al.
Kaixi Li et al.
Alpha-methyltryptamine (AMT), 5-methoxy-alpha-methyltryptamine (5-MeO-AMT), and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT) are three synthetic tryptamines with hallucinogenic properties that are widely abused worldwide. The hallucinog...
Behavioral competition between infant care and sexual behavior in male but not female common marmosets [0.03%]
在雄性而非雌性狨猴中照顾幼崽和性行为之间的行为竞争
Takuma Kurachi,Kazutaka Shinozuka,Chihiro Yoshihara et al.
Takuma Kurachi et al.
Sexual desire and parenthood sometimes compete in a sexually dimorphic manner, but the neural mechanism for this remains to be clarified. Here we show that, in the family-living primate common marmoset, fathers temporarily reduce infant car...
Inflammation and autophagy in peripheral nerves of rodent models with metabolic syndrome and type 2 diabetes mellitus [0.03%]
代谢综合征和2型糖尿病小鼠周围神经炎症与自噬的研究
Petra Baum,Thomas Ebert,Nora Klöting et al.
Petra Baum et al.
Metabolic syndrome (MetS) and type 2 diabetes mellitus (T2D) are associated with inflammation and the accumulation of macrophages in peripheral nerves, which increases the risk of developing peripheral neuropathy (PN). We have previously in...
The impact of brand longevity on consumers' purchase intention: An ERP study [0.03%]
品牌持久度对消费者购买意向的影响：一项ERP研究
Jianhua Liu
Jianhua Liu
This study aims to investigate the neural correlates of brand longevity on consumers' purchase intention by applying the event-related potentials (ERP) method. Behaviorally, in contrast to the short longevity condition, participants in the ...
Soomin C Song,Robert C Froemke
Soomin C Song
Most offspring are born helpless, requiring intense caregiving from parents especially during the first few days of neonatal life. For many species, infant cries are a primary signal used by parents to provide caregiving. Previously we and ...
A practical guide for single-cell transcriptome data analysis in neuroscience [0.03%]
神经科学中单细胞转录组数据分析的实用指南
Yoshinori Hayakawa,Haruka Ozaki
Yoshinori Hayakawa
Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the single-cell level, providing unprecedented insights into cellular heterogeneity, rare cell populations, and dynamic cellular processes. ...
Enhancement of beta rebound elicited by proprioceptive stimulation in the sensorimotor cortex by transcranial alternating current stimulation matched to the dominant beta frequency [0.03%]
与主导beta频率相匹配的经颅交流电刺激在感觉运动皮层中提高由本体感受刺激引发的beta反弹
Mayu Akaiwa,Ryo Kurokawa,Yuya Matsuda et al.
Mayu Akaiwa et al.
Transcranial alternating current stimulation (tACS) can modulate endogenous brain oscillations in a frequency-specific manner. Previous studies have reported that beta tACS modulates the excitability of primary motor cortex and improves tas...