Role of endogenous NT-3 in neuronal activity and neurogenesis in the hippocampal dentate gyrus [0.03%]
内源性NT-3在海马齿状回神经活动和神经发生中的作用
Nanami Kasakura,Yuka Murata,Kanzo Suzuki et al.
Nanami Kasakura et al.
Neurotrophin-3 (NT-3) is a neurotrophic factor that regulates neuronal differentiation and synaptic plasticity. In the adult central nervous system, NT-3 is predominantly expressed in the hippocampal dentate gyrus (DG). Chronic antidepressa...
Synaptic plasticity induced by CA1 synaptic input with bursts superimposed on low-frequency rhythms [0.03%]
由低频节律性放电叠加的脉冲诱导的海马CA1区突触可塑性
Satoshi Fujii,Yoshihiko Yamazaki,Hiroki Fujiwara et al.
Satoshi Fujii et al.
Hippocampal neurons fire synchronously in a population at low frequencies and burst individually at high frequencies, with synaptic plasticity thought to depend on the interplay of these firing patterns. This study investigated synaptic pla...
Whole-brain long-range connectivity of glutamatergic, GABAergic, parvalbumin-expressing and somatostatin-expressing neurons in mouse somatosensory cortex [0.03%]
小鼠体感皮层谷氨酸能、GABA能、parvalbumin阳性和somatostatin阳性神经元的全脑长程连接图谱
Zhaoxin Zhu,Tao Jiang,Xueyan Jia et al.
Zhaoxin Zhu et al.
Understanding the composition of cortical circuits at the whole-brain scale is crucial. However, the specific ways in which particular neuronal types in the primary somatosensory cortex (SSp) establish connections with upstream and downstre...
Possible role of mosaic mutations of neurodevelopmental disorder-related genes in bipolar disorder: lessons from Kmt2c chimeric knockout mice [0.03%]
神经发育相关基因嵌合突变在双相情感障碍中可能的作用：来自Kmt2c嵌合敲除小鼠的启示
Takumi Nakamura,Kazuo Nakajima,Noriko Fujimori-Tonou et al.
Takumi Nakamura et al.
We recently found a loss of function mosaic mutation of KMT2C, a causative gene for autism spectrum disorder and Kleefstra syndrome, in a patient with bipolar disorder and reported that somatic mutations in neurodevelopmental disorder-relat...
Long-lasting expression of FosB/ΔFosB immunoreactivity following acute stress in the paraventricular and supraoptic nuclei of the rat hypothalamus [0.03%]
大鼠下丘脑视上核和室旁核内急性应激后FosB/ΔFosB免疫反应性的长时间表达
Katsuya Uchida,Gopal Das,Ashraf H Talukder et al.
Katsuya Uchida et al.
We examined expression profiles of FosB/∆FosB immunoreactivity and fosB gene transcripts in the paraventricular nucleus of the hypothalamus (PVH) and the supraoptic nucleus (SON) of rats following acute surgical stress (SS) and restraint s...
Endogenously generated patterns of neural activity sculpt axon connectivity [0.03%]
内在产生的神经活动模式塑造轴突连接性
Naoyuki Matsumoto
Naoyuki Matsumoto
Neural activity is crucial in establishing functional circuit connectivity in the central nervous system. Prior to the onset of sensory experience, sensory organs spontaneously generate patterned neural activity, which is essential for scul...
Shimpei Ishiyama
Shimpei Ishiyama
Ticklishness is an idiosyncratic form of touch observed in multiple animal species, including humans. Although commonly regarded as trivial, it involves complex neurobiological mechanisms and diverse behavioral phenomena observed across spe...
Projection-specific and reversible functional blockage in the association cortex of macaque monkeys [0.03%]
猕猴联系皮层的投射特异性和可逆的功能阻滞
Seiichirou Yokoo,Takayasu Higo,Florian Gerard-Mercier et al.
Seiichirou Yokoo et al.
The functional manipulation techniques based on optogenetics have been widely and effectively utilized in the rodent brain. However, the applications of these techniques to the macaque cerebral cortex, particularly those to the prefrontal c...
Beta-band power modulation in the human amygdala during a Direct Reach arm reaching task [0.03%]
直接抓取任务中人类杏仁体的β频段振幅变化特征研究
Jonathon Cavaleri,Shivani Sundaram,Roberto Martin Del Campo-Vera et al.
Jonathon Cavaleri et al.
The human amygdala is primarily known for its involvement in processing emotional and fearful responses, but newer evidence has identified a role for this structure in motor processing. Our lab previously utilized an arm-reaching task and o...
Young fecal microbiota transplantation improves working memory in aged recipient rats by increasing interleukin-4 and interleukin-17 levels [0.03%]
年轻供体粪菌移植通过提高老年受体IL-4和IL-17水平来改善其工作记忆能力
Yiru Yin,Meiqi Guan,Shufen Wu et al.
Yiru Yin et al.
While transplanting the fecal microbiota from young to aged rodents has been extensively studied (that is, young FMT [yFMT]), its mechanism of alleviating working memory decline has not been fully elucidated. In this report, we aimed to inv...