Neuroprotective Effects of SELFormer-Selected β-Citronellol and β-Caryophyllene in Vagotomized Ischemic Stroke Model Through Direct Brain Protection and Gut Microbiota Modulation [0.03%]
SELFormer选择的牻牛儿醇和石竹烯通过直接脑保护和调节肠道菌群在迷走神经切断的缺血性卒中模型中的神经保护作用
Yu Yue,Chen Li,Ting Zhang et al.
Yu Yue et al.
Natural compounds identified via the SELFormer pipeline for cognitive enhancement may exert neuroprotective effects in ischemic stroke (IS) through both direct actions on the central nervous system and potential modulation of the gut microb...
Mitochondria-Targeting SIRT3 Activator Effectively Controls Bleomycin-Induced Pulmonary Fibrosis [0.03%]
线粒体靶向SIRT3激活剂有效控制顺铂引起的肺纤维化
Geetanjali Devabattula,Bulti Bakchi,Anamika Sharma et al.
Geetanjali Devabattula et al.
Pulmonary fibrosis is a debilitating condition characterized by excessive collagen deposition and scar formation. Divergent factors often contribute to mitochondrial dysfunction. Oxidative stress is one of the major triggers for the develop...
LINC01783 Promotes Glioma Tumorigenesis by Enhancing GATA3 Expression Through CBP-Mediated H3K27 Acetylation to Suppress PTEN Expression [0.03%]
长链非编码RNA LINC01783通过CBP介导的H3K27乙酰化促进GATA3表达来抑制PTEN表达从而促进胶质瘤发生发展
Shaocai Hao,Linlin Wang,Shengyu Sun et al.
Shaocai Hao et al.
This study aims to investigate for the first time the functional role and underlying mechanisms of long intergenic non-coding RNA LINC01783 in glioma progression and development. Glioma tumor tissues of different grades, normal brain tissue...
Phenolic Ethanolic Extracts of Specialty Sorghum Ameliorate Intestinal Colitis and Inflammation Induced by Dextran Sulfate Sodium in Mice [0.03%]
特色高粱的酚类乙醇提取物可改善DSS诱导的小鼠肠道结肠炎和炎症
Ibtesam Sleem,Abby Rodriguez,Bingqi Chen et al.
Ibtesam Sleem et al.
Recently, sorghum [Sorghum bicolor (L.) Moench] has been given great attention as an excellent source of polyphenols that exhibit protective effects against multiple chronic disease models. Ulcerative colitis (UC) is strongly linked to the ...
Natural Product Daidzin Inhibits Glioma Development via Suppressing the LRP5-Mediated GSK-3β/c-Myc Signaling Pathway [0.03%]
天然产物大豆黄素通过抑制LRP5介导的GSK-3β/c-Myc信号通路抑制胶质瘤发展
Yijing Pan,Shunshun Wang,Guoliang Duan et al.
Yijing Pan et al.
Daidzin (DZN) is a natural flavonoid compound derived from soybeans that has recently been recognized for its potential antitumor properties. In traditional Chinese medicine, soybeans and their extracts are extensively used to prevent and t...
Unlocking the Antiadipogenic Potential of Carotenoids From Galdieria phlegrea [0.03%]
解开心形栖热藻类胡萝卜素的抗肥胖潜力之门
Enrica Giustino,Paola Imbimbo,Jenifer Trepiana et al.
Enrica Giustino et al.
Oxidative stress, a sedentary and inactive lifestyle, or a high-fat diet are among the main causes responsible for the alteration of skin topography, a complex multifactorial disorder of the deeper layers of the skin, mainly caused by an im...
The Potential Role of Matrix Metalloproteinase in Polycystic Ovary Syndrome: Implications for Extracellular Matrix Remodeling [0.03%]
基质金属蛋白酶在多囊卵巢综合征中潜在作用：细胞外基质重塑意义
Saba Nikanfar,Christiani A Amorim
Saba Nikanfar
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and a leading cause of infertility primarily due to impaired folliculogenesis and anovulation. Central to ovarian function and follicular development is the extracellular ma...
The Immunotherapeutic Target ANLN Promotes Renal Clear Cell Carcinoma by Regulating PI3K/Akt and P53 Signaling Pathways [0.03%]
ANLN通过调节PI3K/Akt和P53信号通路促进肾透明细胞癌的免疫治疗靶点
Li Shan,Guo-Jian Gu,Cheng-Cheng Xiang et al.
Li Shan et al.
The role of Anillin (ANLN) in clear cell renal cell carcinoma (ccRCC) is not well understood. This study aimed to investigate the possible function and mechanism of ANLN in ccRCC. By using data from the Cancer Genome Atlas (TCGA), we assess...
Correction to "Untargeted metabolomics reveals biomarkers for the diagnosis of coronary artery plaques as observed by coronary cardiac computed tomography" [0.03%]
对“非靶向代谢组学发现冠状动脉斑块的诊断生物标志物——由心脏冠状计算机断层扫描观察到”的勘误通知
Published Erratum
BioFactors (Oxford, England). 2025 May-Jun;51(3):e70019. DOI:10.1002/biof.70019 2025
EVs Biodistribution and Antifibrotic Impact in Aged Lung Fibrosis Model [0.03%]
外源性血管生成因子的生物分布及其在年老肺纤维化模型中的抗纤维化作用研究
Ilias Amtil-Ouahdi,Fabián Vergara,Carlos Rio et al.
Ilias Amtil-Ouahdi et al.
Pulmonary fibrosis (PF) is a progressive, life-threatening disease marked by excessive scarring of lung tissue. Recently, extracellular vesicles (EVs) have emerged as a promising antifibrotic therapy due to their regenerative and anti-infla...