Dan Fayette,Veronika Juríčková,Tomáš Kozák et al.
Dan Fayette et al.
Chemotherapy-related cognitive impairment (CRCI) is a well-documented side effect of cancer treatment in various types of tumors including Hodgkin's lymphoma (HL). However, a longitudinal study evaluating the cognitive performance of HL pat...
Several reasons why ketamine as a neuroplastic agent may have failed to prevent postoperative delirium: Implications for future protocols [0.03%]
作为神经可塑性剂的氯胺酮可能无法预防术后谵妄的几个原因：对未来协议的影响
Jiri Horacek,Robert Janda,Natalie Görnerova et al.
Jiri Horacek et al.
Ketamine exerts anti-inflammatory, neuroprotective and neuroplastic activity, therefore it may counteract the neurotoxic processes underlying postoperative delirium. However, the majority of studies in this field failed. We identified sever...
Circadian functioning of Locus Cœruleus of the nocturnal rat and diurnal rodent Arvicanthis [0.03%]
夜行性 rats 和昼行性啮齿动物 Arvicanthis 蓝斑的生理节奏功能研究
Rosanna Caputo,Vincent-Joseph Poirel,Isabel Paiva et al.
Rosanna Caputo et al.
The noradrenergic Locus Cœruleus is one of the major arousal structures involved in inducing wakefulness. While brain noradrenaline (NA) amounts display 24-h variations, the origin of NA rhythm is currently unknown. In this study, we teste...
The lectin from Schinus terebinthifolia leaf (SteLL) reduces immobility of mice on the tail suspension test dependent on the monoaminergic and nitric oxide signaling [0.03%]
来自月桂南漆树叶的凝集素(SteLL)依赖单胺能和一氧化氮信号降低尾悬测试中老鼠的不动时间
Bárbara Raíssa Ferreira de Lima,Leydianne Leite de Siqueira Patriota,Amanda de Oliveira Marinho et al.
Bárbara Raíssa Ferreira de Lima et al.
Depression underlies a common psychiatric disorder that has been rising in the diagnosis of long-term disabilities worldwide. Natural products have been studied as an antidepressant and anxiolytic agents aiming to make available new options...
Neuroprotective potential of Honokiol in ICV-STZ induced neuroinflammation, Aβ (1-42) and NF-kB expression in experimental model of rats [0.03%]
Honokiol在ICV-STZ诱导的大鼠神经炎症、Aβ(1-42)和NF-kB表达的实验模型中的神经营养潜力
Lovekesh Singh,Shamsher Singh
Lovekesh Singh
Alzheimer's disease (AD) is a most common and prevalent age related insidious neurological condition characterised by formation of Aβ (1-42) plaques and NFT in the hippocampus. Major symptoms of AD include memory and cognitive loss caused ...
The impact of traumatic brain injury on inhibitory control processes assessed using a delayed antisaccade task [0.03%]
利用延迟反扫视任务评估创伤性脑损伤对抑制控制过程的影响
Revathy Mani,Lisa Asper,Valarmathi Arunachalam et al.
Revathy Mani et al.
It has been well established that traumatic brain injury (TBI) can affect cognitive function such as attention, working memory and executive functions. In the present study, we further investigated TBI-related changes in cognitive functions...
Tatsunori Watanabe,Atsunori Itagaki,Akira Hashizume et al.
Tatsunori Watanabe et al.
In animal models, oscillations of local field potentials are entrained by nasal respiration at the frequency of breathing cycle in olfactory brain regions, such as the olfactory bulb and piriform cortex, as well as in the other brain region...
BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPTP301S mouse model of tauopathy [0.03%]
BCI-838是一种口服活性的mGluR2/3受体拮抗前药，在tauopathy的小鼠模型PS19 MAPTP301S中可挽救学习行为缺陷
Georgina Perez-Garcia,Mesude Bicak,Jean-Vianney Haure-Mirande et al.
Georgina Perez-Garcia et al.
Tauopathies are a heterogeneous group of neurodegenerative disorders that are clinically and pathologically distinct from Alzheimer's disease (AD) having tau inclusions in neurons and/or glia as their most prominent neuropathological featur...
Brain activation and individual differences of emotional perception and imagery in healthy adults: A functional near-infrared spectroscopy (fNIRS) study [0.03%]
健康成人情绪感知和想象的脑激活及个体差异:fNIRS研究
Li Zhou,Biyun Wu,Yuanyuan Deng et al.
Li Zhou et al.
The current study investigated the brain activation and individual differences in perception and imagery of sad pictures versus happy and neutral pictures. Sixty-eight healthy adults were instructed to view and visualize sad, happy, and neu...
Upregulations of α1 adrenergic receptors and noradrenaline synthases in the medial prefrontal cortex are associated with emotional and cognitive dysregulation induced by post-weaning social isolation in male rats [0.03%]
断奶后社交隔离导致雄性大鼠腹侧前额皮层α1肾上腺素能受体和去甲肾上腺素合酶的上调表达与情绪和认知失调有关
Shunsuke Kawanabe,Masayoshi Mori,Hiroyoshi Harada et al.
Shunsuke Kawanabe et al.
Early-life social isolation induces emotional and cognitive dysregulation, such as increased aggression and anxiety, and decreases neuron excitability in the medial prefrontal cortex (mPFC). The noradrenergic system in the mPFC regulates em...