Relationship between prefrontal oxygenation during task-set period and executive function in healthy older people: A near-infrared spectroscopy study [0.03%]
近红外光谱技术在任务集周期期间健康老年人前额氧合与执行功能之间关系的研究
Yumi Oboshi,Mitsuru Kikuchi,Yasuomi Ouchi
Yumi Oboshi
Introduction: In past research, we have examined the characteristics of brain activity caused by prefrontal task completion in healthy older adults in a simplified manner using a near-infrared spectroscopy device, with th...
Nicotine exacerbates fear and depression-like behaviors by promoting microglial phagocytosis of synaptic protein in a mouse model of foot shock [0.03%]
尼古丁通过促进小胶质细胞吞噬足 shock鼠模型中突触蛋白来加剧恐惧和类似抑郁的行为
Jiaquan Wang,Xiao-Kang Gong,Jing Yu et al.
Jiaquan Wang et al.
Post-traumatic stress disorder (PTSD) is a severe psychiatric disorder characterized by a complex interplay of genetic and environmental influences. Substantial evidence has demonstrated an intricate nexus between nicotine, the principal ps...
Short-term effects of sertraline against depressive-like behaviors in a rat model of neonatal hypoxic encephalopathy [0.03%]
舍曲林对新生儿缺氧性脑病大鼠抑郁样行为的短期干预作用
Marie-Michèle Serghani,Sondos Kassem-Moussa,Rawan Makki et al.
Marie-Michèle Serghani et al.
Hypoxic encephalopathy of the newborn is associated with long-term neurodevelopmental behavioral deficits that lack a definitive "optimal" treatment approach. We previously demonstrated that periadolescent depressive-like behaviors occur in...
Tanshinone IIA and hydroxy safflower yellow A reduce cerebral injury via TLR4/NF-κB pathway in rats [0.03%]
丹参酮 ⅡA 和羟基红花黄色素 A 通过 Toll 样受体 4/核因子 κB 信号途径减少大鼠脑损伤
Bin Luo,Yu Zheng,Qi Miao et al.
Bin Luo et al.
Cerebral ischemia-reperfusion injury (CIRI) is a cerebrovascular disorder with high rates of incidence, disability, and death. It has been identified that Salvia miltiorrhiza and safflower have a protective effect in CIRI. However, the mech...
Blockade of acid-sensing ion channels 1a in the mice dorsal raphe nucleus inhibits panic-like responses: Role of 5-HT1A receptors in the dorsal periaqueductal gray [0.03%]
阻滞小鼠延髓背核酸感受器离子通道1a抑制惊恐反应：脑干导水管周围灰质5-HT₁A受体的作用
Alana Tercino Frias,Paloma Molina Hernandes,Helio Zangrossi Jr
Alana Tercino Frias
Panic attacks, characterized by intense fear accompanied by autonomic and respiratory changes, can be experimentally modeled in humans and rodents by exposure to high concentrations of CO2. Acid-sensing ion channels (ASICs), particularly th...
Vitamin D3 alleviates AD-like pathology in APP/PS1 mice by inhibiting pyroptosis and neuroinflammation via DJ-1/PARK7 [0.03%]
维生素D3通过DJ-1/PARK7抑制APP/PS1小鼠的焦亡和神经炎症以缓解AD样病理损害
Chunyu Zhou,Yulin Wang,Longfei Zuo et al.
Chunyu Zhou et al.
Alzheimer's disease (AD) is the most common primary progressive neurodegenerative disorder, with inflammatory responses involved in its onset and progression. Vitamin D (VD) is known for its health benefits, including antioxidant effects. R...
Mini-Review: Cathodal tDCS over the right prefrontal cortex and inhibitory control: Pinpointing an electrode montage to disrupt a domain-general system [0.03%]
短篇综述：右侧前额叶 cathodal tDCS 和抑制控制：破坏一般领域系统的电极蒙太奇定位
Carlos J Gómez-Ariza,Javier Pacios
Carlos J Gómez-Ariza
While many tDCS studies have focused on enhancing inhibitory control, only a few have employed tDCS to disrupt the neural activity of specific brain regions and gain understanding of their contribution to inhibitory control. This mini-revie...
Dynamic current-clamp unveiling the indispensable interplay between Nav1.7 and Nav1.8 for shaping action potential trajectory and retaining neuroexcitation of visceral sensory neurons [0.03%]
动态电流钳技术揭示Nav1.7和Nav1.8对内脏感觉神经元动作电位轨迹塑形及维持神经兴奋性的不可或缺作用
Ying Li,Chen Zhang,Limin Han et al.
Ying Li et al.
Tetrodotoxin (TTX)-sensitive/Nav1.7- and TTX-resistive/Nav1.8 Na+ channels contribute to neuroexcitation in the sensory neurons of the nodose ganglion (NG); however, their specific roles remain debatable. Therefore, we aimed to study the ac...
COPII component Sec13 is required for peripheral myelination and Schwann cell maintenance [0.03%]
COPII成分Sec13对于神经髓鞘形成和施万细胞稳态维持是必需的
Debao Wu,Zhenghao Li,Xiaoyun Lu et al.
Debao Wu et al.
Peripheral nerve myelination critically relies on the timely and efficient delivery of myelin proteins and membranes. Although Coat Protein Complex II (COPII) is a canonical vesicular trafficking machinery, the cell-type-specific functions ...
Acute restraint stress and epinephrine administration disrupt cognitive and emotional functions in male rats via modulation of proinflammatory cytokines, MCT-2, and neurogranin [0.03%]
急性束缚应激和肾上腺素处理通过调节促炎症细胞因子、单羧酸转运蛋白-2和星形胶质纤维酸性蛋白影响雄性大鼠的认知和情绪功能
Zehra Sezgın,Hale Sayan Ozacmak,Incı Turan
Zehra Sezgın
Stress triggers neuroendocrine and physiological changes, often resulting in cognitive impairments and heightened anxiety. This study aims to investigate the effects of acute stress and epinephrine administration on learning, memory, and an...