The PTM Switches of HBx: Master Regulators of HBV Infection and Liver Oncogenesis [0.03%]
HBx的PTM转换开关：HBV感染和肝癌发生的主调控因子
Zubing Ye,Meijuan Ma,Di Yu et al.
Zubing Ye et al.
The hepatitis B virus (HBV) X protein (HBx) functions as a versatile regulatory molecule that is indispensable for both efficient HBV replication and the pathogenesis of HBV-related hepatocellular carcinoma (HCC). Accumulating studies indic...
Physicochemical fingerprinting reveals convergent evolutionary determinants of enterovirus A71 neurovirulence through integrative machine learning and structural analysis [0.03%]
基于集成机器学习和结构分析的肠道病毒A71神经毒性的收敛进化决定因素的物理化学指纹识别
Xiaoqian Wang,Feng Li
Xiaoqian Wang
Enterovirus A71 (EV-A71) causes hand, foot, and mouth disease and can trigger life-threatening neurological complications, yet the sequence-level physicochemical correlates of CNS involvement across globally circulating lineages remain inco...
Pathogenicity and Molecular Evolutionary Analysis of Novel Avian orthreovirus Genotypes IV and V in Upper Egypt [0.03%]
埃及上部新型禽病毒第四和第五基因型的致病性和分子进化分析
Doha Abd Alrahman Ahmed,Shimaa Mohamed Ali Ahmed Khair,Mohammed A GamalEldin et al.
Doha Abd Alrahman Ahmed et al.
Avian orthoreovirus (ARV) imposes substantial economic losses on the global poultry industry, primarily through runting-stunting syndrome and viral arthritis. Despite its global prevalence, the molecular epidemiology and pathogenic landscap...
Expanded virome analysis of metatranscriptomes from grapevine downy mildew lesions reveals novel viral segments, novel viruses and viroid-like RNAs [0.03%]
葡萄霜霉病病变的元转录组扩增病毒分析揭示了新的病毒片段、新病毒和类似viroid的RNA
Stefania Daghino,Marco Forgia,Francesco Di Serio et al.
Stefania Daghino et al.
Grapevine downy mildew, caused by the obligate biotrophic oomycete Plasmopara viticola, represents a major constraint to viticulture worldwide. Previous metatranscriptomic analyses revealed an unexpectedly rich viral diversity associated wi...
New Iflavirus identified in Chiroxiphia pareola birds from an ecotone area in northeast Brazil [0.03%]
巴西东北部生态交错带地区Chiroxiphia pareola鸟类中新Iflavirus的鉴定
Lizandra Caroline Dos Santos Souto,Flávio Kulaif Ubaid,Leonardo Henrique Almeida Hernández et al.
Lizandra Caroline Dos Santos Souto et al.
Avian species play a key role in the ecology of viruses, acting as reservoirs, sentinels, and biological carriers across diverse environments. Here, we describe the detection and genomic characterization of a novel iflavirus identified in f...
Transcriptome analysis of African swine fever virus I9R-mediated modulation of host antiviral immunity [0.03%]
非洲猪瘟病毒I9R蛋白介导的宿主抗病毒免疫调控机制研究
Yan Lijiao,Zhou Yanlong,Ren Jingjing et al.
Yan Lijiao et al.
African swine fever (ASF) is an acute hemorrhagic disease caused by African swine fever virus (ASFV), with mortality rates approaching 100% in domestic pigs. Because its genome is large and structurally complex, the functions of many ASFV e...
Corrigendum to "Two target cells for HPV infection at the cervix?" [Virus Res. 2026 , 369, 199754] [0.03%]
“宫颈HPV感染的两个靶细胞？”[病毒研究，2026 ，369，199754]的勘误通知
O Reich,S Regauer
O Reich
Published Erratum
Virus research. 2026 Jul 3:199774. DOI:10.1016/j.virusres.2026.199774 2026
Vaccination with an HSV-1 virus containing CD-137L reduces herpetic corneal disease when used both prophylactically and therapeutically [0.03%]
用含有CD-137L的HSV-1病毒疫苗预防和治疗 herpes感染都可降低疱疹性角膜病的效果
Patrick M Stuart,Ziao-Tang Yin
Patrick M Stuart
Corneal infections with herpes simplex type 1 (HSV-1) are a leading cause of blindness in the world. At present the standard of care for corneal disease (herpetic stromal keratitis, HSK) is anti-virals and topical steroids. With the develop...
Ondansetron exhibits potent antiviral activity against enterovirus 71 infection in vitro and in vivo [0.03%]
昂丹司琼对肠道病毒71感染体内外具有强力的抗病毒活性
Zhenyang Li,Jianqiao Rui,Jiazheng Li et al.
Zhenyang Li et al.
Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) with neurotropism, and currently no approved antiviral therapies are available. In this study, we found that the ondansetron exhibits antiviral acti...
Case report: A case of HIV seroconversion in a high-risk individual after 35 years of resistance with a CCR5Δ32 heterozygous genotype [0.03%]
案例报告：CCR5Δ32杂合子型高危个体35年后发生HIV血清转化病例报告
Najib Aziz,Eun-Young Kim,Beth D Jamieson et al.
Najib Aziz et al.
Numerous studies have examined the factors contributing to the variation in disease progression among people living with HIV-1, identifying a range of genetic, immunologic and virologic factors that interact in a complex, multifactorial dyn...