Neurotoxic effects of binary and ternary fungicide mixtures in developing zebrafish: A multi-endpoint assessment [0.03%]
开发中的斑马鱼二元和多元杀菌剂混合物的神经毒性作用:多终点评估
Annamaria Iannetta,Irene Masciola,Tommaso Silvestrini et al.
Annamaria Iannetta et al.
Folpet (F), penconazole (P), and metrafenone (M) are commonly used fungicides. Their toxicological effects, particularly in mixtures, are not sufficiently understood. Zebrafish embryos were treated for 96 hpf with single compounds, binary a...
Epithelial effects of exposure to e-cigarettes alone or in combination with cigarette smoke using multicellular lung mucosa models [0.03%]
仅使用电子烟或与卷烟烟雾结合暴露对上皮的影响——多细胞肺粘膜模型研究
Shanzina Iasmin Sompa,Swapna Upadhyay,Koustav Ganguly et al.
Shanzina Iasmin Sompa et al.
Pulmonary molecular toxicity data on electronic (e)-cigarettes, alone or in combination with cigarette smoke, remain limited. We developed air-liquid interface bronchial and alveolar lung mucosa models using primary human bronchial epitheli...
Exposure effects to the harmful algal bloom (HAB)-dependent marine biotoxin domoic acid on the antioxidant network of the mussel Mytilus edulis platensis [0.03%]
皱纹盘鲍抗氧化系统对有害藻华依赖性海洋生物毒素DOM的响应研究
Agustin Caiciia Massello,Susana Puntarulo,Paula Mariela González
Agustin Caiciia Massello
The objective was to study domoic acid (DA) effects on the oxidative status and antioxidant system in Mytilus edulis platensis digestive glands (DG) and hemocytes. Reactive species in DG showed increases at 30 and 64µM DA, and in hemocytes...
Serum Perfluoroalkyl Substances and Infant Measles Antibody Concentrations Before and After Vaccination: Results from Burkina Faso [0.03%]
布基纳法索血清中的全氟烷基物质和婴儿接种疫苗前后预防麻疹的抗体浓度水平的关系研究
Sarah Dencker Mikkelsen,Ane Bærent Fisker,Eric Ipyn Nebie et al.
Sarah Dencker Mikkelsen et al.
Perfluoroalkyl substances (PFAS) have been linked to immunotoxic effects in children, and the consequences of immune suppression could be particularly severe for children in low-income settings. We thus aimed to investigate associations bet...
Prenatal exposure to organophosphate esters: Evidence of sex-specific risks for maternal and neonatal health [0.03%]
孕期接触磷酸酯类物质:关于对母体和新生儿健康存在性别特异性风险的证据
Xing Liao,Hongping Zhao,Shuhan Li et al.
Xing Liao et al.
Organophosphate esters (OPEs) are emerging endocrine-disrupting chemicals, yet their sex-specific effects on maternal and neonatal health remain unclear. This study quantified eleven OPEs in 467 maternal serum samples and examined their ass...
Integrated Ecotoxicological Assessment of Nerol: Comparative Sensitivity on Allium cepa, Aliivibrio fischeri, Daphnia magna, Eisenia fetida, and Riverine Water and Soil Microbial Communities [0.03%]
柠檬烯的综合生态毒性评价及其对葱、费舍弧菌、大型蚤、赤子爱胜蚓和河流水体及土壤微生物群落的影响研究
Guillermo Lorca,María Rosa Pino-Otín,Pedro Rodríguez-López et al.
Guillermo Lorca et al.
Nerol (NE), a monoterpene of plant origin, was evaluated through an integrated ecotoxicological study. Median effective concentration (EC50) of NE on individual bioindicators named Aliivibrio fischeri, Daphnia magna, Allium cepa, and Eiseni...
The pharmacokinetics of tolfenamic acid in Himalayan Griffon vultures. A better understanding for the safety of the drug in old world vultures [0.03%]
托芬那酸在喜马拉雅 Griffon 兀鹫体内的药代动力学研究:更好地理解该药物在旧大陆兀鹫中的安全性
Paul-Hendri van der Merwe,Karikalan Mathesh,Vibhu Prakash et al.
Paul-Hendri van der Merwe et al.
The pharmacokinetics of tolfenamic acid (TA) was determined for Himalayan Griffon vultures from published data. The evaluation included 38 birds dosed orally at 3.2-3.7 mg/kg, of which 2 unscheduled deaths were recorded. The maximum concent...
Antioxidant battery alterations in a Mexican child population living near pesticide use intensive areas [0.03%]
墨西哥一个居住在农药密集使用区的儿童群体中的抗氧化剂电池改变现象
Miguel Alfonso Ruiz-Arias,Yael Yvette Bernal-Hernández,Irma Martha Medina-Díaz et al.
Miguel Alfonso Ruiz-Arias et al.
Environmental pesticide exposure is a major concern for children's health. A cross-sectional study was conducted in children from two agricultural communities and one reference community to evaluate antioxidant status in relation to pestici...
The behavioural, toxicological, and biochemical effects of caffeine on Lumbriculus variegatus [0.03%]
咖啡因对Lumbriculus variegatus的行为学、毒理学和生化作用效应
Grace E Labdon,Roisin Kelly-Laubscher,Margaret R Cunningham et al.
Grace E Labdon et al.
Caffeine is an emerging contaminant of concern frequently detected in freshwater systems, yet the behavioural, toxicological and biochemical effects of caffeine in aquatic invertebrates remain poorly characterised. Here, we investigate the ...
Molecular Mimicry in the Agroecosystem: A New Paradigm for Understanding How Pesticide Residues Drive the Emergence of Antimicrobial Resistance [0.03%]
农业生态系统中的分子模拟:理解农药残留如何驱动抗菌药物耐药性产生的一种新范式
Domenico Britti
Domenico Britti
Antimicrobial resistance (AMR) is a mounting global crisis, with environmental dissemination of antibiotic resistance genes (ARGs) emerging as a critical driver. Agroecosystems, chronically exposed to complex mixtures of bioactive chemicals...