Spatial distribution of long-term ultrafine particle concentrations and systemic lupus erythematosus burden in central Mexico [0.03%]
墨西哥中部长期超细颗粒物浓度的空间分布及系统性红斑狼疮负担
Jesús Guerrero-Morales,Ivet Etchegaray-Morales,Pamela Munguía-Realpozo et al.
Jesús Guerrero-Morales et al.
Long-term ultrafine particle (UFP) concentrations may reflect urban particulate pollution contexts relevant to autoimmune disease burden, yet evidence from middle-income countries remains limited. We characterized spatial patterns of munici...
Sublethal pesticide effects, synergistic interactions and resilience strategies in honey bees (Apis mellifera): A narrative review [0.03%]
杀蜂虫剂亚致死效应、协同作用及增强蜜蜂（Apis mellifera）复原力的策略：综述论文
Roberto Bava,Fabio Castagna,Stefano Ruga et al.
Roberto Bava et al.
Pesticide exposure at chronic, field-realistic doses represents a major driver of honey bee colony weakening through sublethal and synergistic effects. This narrative review synthesizes evidence from 2010 to 2025 on neurophysiological, immu...
Air pollution and undernutrition induce rat alveolar macrophages functional dysregulation and compromise their response to a viral challenge [0.03%]
空气污染和营养不良会诱导大鼠肺泡巨噬细胞功能失调并损害其应对病毒刺激的反应
Ivana Masci,Christian Lezón,Melisa Kurtz et al.
Ivana Masci et al.
Air pollution and undernutrition are major global health problems that frequently coexist in vulnerable populations and may interact to impair pulmonary immune defenses. We investigated how chronic undernutrition influences alveolar macroph...
Fluoride induced chondrocyte extracellular matrix degradation by inhibition of glycolysis by the PHD2/HIF1α signaling pathway [0.03%]
富马酸亚铁通过PHD2/HIF1α信号途径抑制糖酵解诱导软骨细胞外基质降解
Yu Gui,Rui Ma,Lan Ma et al.
Yu Gui et al.
Studies have shown that fluoride induces cartilage damage, however, the specific mechanism is unknown. In this study, we investigated the effect of fluoride on extracellular matrix metabolism and its molecular regulatory mechanism, using we...
Evaluation of the impact of deltamethrin, dapagliflozin, and KB-R7943 on INa in HL-1 atrial myocytes and U2OS osteosarcoma cells: An investigative study [0.03%]
评估deltamethrin、dapagliflozin和KB-R7943对HL-1心房肌细胞和U2OS骨肉瘤细胞INa的影响：一项调查研究
Sheng-Che Lin,Yang-Kao Wang,Sheng-Nan Wu et al.
Sheng-Che Lin et al.
The effects of deltamethrin (DLT), alone or in combination with dapagliflozin (Dapa) or KB-R7943, on INa were investigated in HL-1 cardiomyocyte and U2OS osteosarcoma cells. DLT increased both transient INa (INa(T)) and tail INa in HL-1 cel...
Integrated plasma proteomics and metabolomes reveal potential biomolecules linking PM2.5 to depression [0.03%]
整合血浆蛋白质组和代谢组揭示PM2.5致抑郁症生物标志物候选分子
Lan Chen,Dashan Zheng,Shengtao Wei et al.
Lan Chen et al.
The biomolecular pathways linking fine particulate matter (PM2.5) and its constituents to depression remain elusive. With 24,940 depression-free participants in the UK Biobank, exposure to PM2.5 and its 5 constituents (ammonium, nitrate, su...
In vitro protective effects of cyanidin-3-O-glucoside against toxicity induced by continuous exposure to antimony(III) in intestinal epithelial cells [0.03%]
花色苷-3-O-糖苷对肠道上皮细胞连续暴露于三价锑诱导的毒性中的保护作用
Federica Lina Salamone,Maria Sofia Molonia,Santi Trischitta et al.
Federica Lina Salamone et al.
Antimony (Sb), a heavy metal employed in PET manufacturing, is an emerging contaminant due to its ability to leach into food and beverages. Chronic exposure can impair intestinal health by disrupting epithelial barrier functionality and pro...
Toxicological assessment of a commercial imidacloprid formulation: Evidence of systemic, oxidative and genotoxic effects in rats [0.03%]
噻虫啉商品制剂的毒理学评估：对大鼠全身毒性、氧化作用和遗传毒性的证据
C A M Tasso,B D Tonietto,N G Dos Santos et al.
C A M Tasso et al.
Imidacloprid (IMI) is a neonicotinoid insecticide used in agriculture, domestic environments, and veterinary medicine. The objective of this study was to evaluate possible toxic effects of an IMI based commercial formulation on oxidative pa...
Behavioral and redox effects of lithium and curcumin in a planarian model of sublethal stress [0.03%]
锂和姜黄素在扁虫亚致死应力模型中的行为和氧化作用效应研究
Rayane Hoffeman de Lima,Victor Eduardo Souza-Aguiar,Welligton Luciano Braguini
Rayane Hoffeman de Lima
Freshwater ecosystems are increasingly contaminated by neuroactive compounds, including lithium (Li) from battery waste and curcumin (CUR) from consumer products, but their sublethal effects on aquatic invertebrates are poorly characterized...
Michael D Coleman
Michael D Coleman
Dapsone possesses anti-infective and anti-imflammatory properties, but its CYP-mediated metabolism to hydroxylamines causes dose-dependent haematological toxicity which impairs patient tolerance. In the 1990s cimetidine-mediated partial inh...