Frailty's fundamental heterogeneity: From biological mechanisms to health equity [0.03%]
衰弱的基本异质性：从生物学机制到健康公平
Liang-Kung Chen
Liang-Kung Chen
From co-design to sustainable practice: Reflections on inclusive physical activity for older adults [0.03%]
从共同设计到可持续实践：促进老年人参与包容性体育活动的反思
Miglė Kiguolytė,Benjamin H L Harris,Louis J Koizia
Miglė Kiguolytė
Inhibition of c-Jun/Bak signaling alleviates endothelial cell senescence and inflammation caused by mitochondrial dysfunction in DMED [0.03%]
c-Jun/ Bak信号通路抑制缓解2型糖尿病血管内皮细胞线粒体功能异常所致的衰老和炎症
Ma Jianxiong,Guo Yingxue,Zhongliao Zeng et al.
Ma Jianxiong et al.
Endothelial dysfunction is a key contributor to diabetic complications, including erectile dysfunction (ED). Using single-cell RNA sequencing and transcriptomic analysis of diabetic ED (DMED), this study identifies the c-Jun/Bak pathway as ...
Development and validation of a modified phenoage for biological aging and chronic diseases in a chinese cohort [0.03%]
适用于中国人群的改良型PhenoAge生物衰老和慢性病预测模型的开发与验证
Jialiang Zheng,Tao Liu,Yumei Luo et al.
Jialiang Zheng et al.
Objective: To address the original PhenoAge's reliance on C-reactive protein (CRP)-a non-routine clinical biomarker-and enhance practical utility in routine healthcare settings, we developed a modified algorithm (PA-CRP) ...
Longitudinal association between pulmonary function and incident cognitive decline : Results of the SONIC cohort study [0.03%]
肺功能与认知功能下降的纵向关系：SONIC队列研究结果
Yuka Tachibana,Keigo Kobayashi,Mai Kabayama et al.
Yuka Tachibana et al.
Reduced pulmonary function may contribute to cognitive decline in older adults; however, few longitudinal studies adjust for frailty, lifestyle, and comorbidities. This study examined whether baseline spirometry predicts 3-year cognitive de...
Watching sports and subsequent health and well-being in older adults: a longitudinal outcome-wide study [0.03%]
观看体育赛事与老年人后续的健康和福祉：一项纵向研究
Taishi Tsuji,Kenjiro Kawaguchi,Kazushige Ide et al.
Taishi Tsuji et al.
Background: Although watching sports has increasingly been associated with mental health benefits among older adults, its broader implications, positive and negative, across diverse health and well-being outcomes remain u...
Is there a compression of morbidity and does it vary across social strata among older European adults? A retrospective cohort study of two waves 15 years apart [0.03%]
欧洲老年人的生活压力及其社会阶层差异：基于15年前后两波队列的回顾性研究
Enrique Alonso-Perez,Julie L O&#x;Sullivan,Jan Paul Heisig et al.
Enrique Alonso-Perez et al.
Background: Compression of morbidity may be linked to belonging to particular social strata defined by intersections of age, gender, migration and occupation. Extending the approach by Crimmins and Beltrán-Sánchez, we i...
Beyond access: Digital skills as a new social determinant of health among older adults - evidence from a longitudinal panel study [0.03%]
超越可及性：老年人口中数字技能作为新的健康社会决定因素的证据——来自纵向面板研究的证据
Hao Ji,Weiguang Pan,Junyi Xin
Hao Ji
Background: As the digital divide shifts from access to skills, the impact of digital competence on older adults' well-being remains underexplored. This study investigates the longitudinal relationship between digital ski...
Heatmap of 10-year disability risk according to the frailty-intrinsic capacity (FR-IC) index in older Japanese adults [0.03%]
日本老年人十年残疾风险热图（脆弱性内在能力指数）
Rei Otsuka,Shu Zhang,Yukiko Nishita et al.
Rei Otsuka et al.
Usefulness of the global leadership initiative on malnutrition -GLIM- criteria to identify malnutrition in older adults: systematic review and meta-analyses [0.03%]
全球营养不良领导倡议(GLIM)标准用于识别老年人营养不良的系统综述和荟萃分析
Gustavo Díaz,Carla M Prado,Maria Cristina Gonzalez et al.
Gustavo Díaz et al.
Aim: Malnutrition is highly prevalent among older subjects, yet no universal method for its identification has been established. This study aimed to evaluate the concurrent and predictive validity of the GLIM criteria in ...