Benefit of home-based virtual reality aerobic exercise combined with resistance training for reversing sarcopenia and reducing depression in community-dwelling older adults with sarcopenia: a randomized control trial [0.03%]
家庭基于虚拟现实有氧运动结合阻力训练逆转社区老年人肌肉减少症及降低抑郁的积极作用：一项随机对照试验
Kornanong Yuenyongchaiwat,Chanakan Chitjamnogchai,Natsinee Sermsinsaithong et al.
Kornanong Yuenyongchaiwat et al.
Background: Sarcopenia is a growing concern owing to an aging global population. Older people with depression are at risk for sarcopenia and vice versa. Although physical exercise is key in preventing and managing sarcope...
Changes of multidimensional frailty among older adults during 2010-2023: A systematic review and cross-temporal meta-analysis [0.03%]
2010年至2023年老年人多维脆弱性变化的系统评价和跨时间Meta分析
Huanle Liu,Bin Chen,Xianying Lu et al.
Huanle Liu et al.
Objective: This study aimed to explore the changing trend of multidimensional frailty among the elderly from 2010 to 2023 and its relationship with social changes. ...
Single-cell transcriptomic analysis reveals the molecular alterations of endothelial cells during ageing [0.03%]
单细胞转录组分析揭示内皮细胞衰老过程中的分子改变
Yongle Sun,Yini Dai,Yehu Yin
Yongle Sun
Ageing of the vasculature is the fundamental cause for the development of cardiovascular diseases. Endothelial cells play an important role in ageing of the cardiovascular system, but the potential mechanisms of vascular ageing and the mole...
Effects of vitamin D intake alone on elderly body composition: A systematic review and meta-analysis of RCTs [0.03%]
单纯维生素D摄入对老年人体组成的影响：随机对照试验的系统评价和meta分析
Tomoyuki Matsuyama,Hiroshi Okada,Yuto Saijo et al.
Tomoyuki Matsuyama et al.
Background: This study investigated the effect of vitamin D on body composition in individuals aged 60 years and older. Methods: PubMed...
Latent transition of social participation and its relationship with frailty among older adults with chronic non-communicable diseases in China: A national longitudinal study [0.03%]
中国老年人慢性非传染性疾病患者的社会参与潜在转变及其与脆弱性的关系：一项全国纵向研究
Zitong Gao,Haihong Qin,Tong Yue et al.
Zitong Gao et al.
Objective: Older adults' social participation is associated with frailty, but the transition patterns and their relationship with frailty remain unclear. This longitudinal study aims to explore the latent classes and tran...
Mortality prediction among older people in primary care: a comparison of predictive performance of the frailty index with regression-based and machine learning models [0.03%]
初级保健中老年患者死亡率预测：与回归和机器学习模型相比的脆弱性指数的预测性能比较
Collin Jc Exmann,Karlijn J Joling,Robert Verheij et al.
Collin Jc Exmann et al.
Introduction: The frailty index is widely used to identify vulnerable individuals at risk of adverse outcomes like mortality. However, its predictive performance compared to other mortality prediction models, especially i...
Association of gut microbiota and arginine-agmatine metabolism with postoperative delirium in elderly patients following lower limb fracture surgery: a prospective nested case-control study [0.03%]
老年人髋部骨折术后谵妄与肠道微生物及精氨酸-瓜氨酸代谢的相关性：一项病例对照研究
Xinyu Cao,Jing Wang,Yv Zhang et al.
Xinyu Cao et al.
Objective: This study aimed to investigate the role of gut microbiota and arginine-agmatine metabolic levels in the pathogenesis of postoperative delirium (POD) in elderly patients following lower limb fracture surgery. ...
Trajectory of depressive symptom before and after incident hearing loss: A 24-year population-based longitudinal cohort study [0.03%]
一项24年的基于人群的纵向队列研究：听力损失事件前后的抑郁症状轨迹
Qin Li,Haohong Lai,Juntao Wu et al.
Qin Li et al.
Background: Although hearing loss (HL) is a known risk factor for depressive symptoms, how depressive symptoms progress after its onset remains insufficiently explored. This study aimed to explore whether incident HL is a...
Timing of daily physical activity and onset of depressive symptoms: A longitudinal cohort study of community-dwelling older adults [0.03%]
每日身体活动的时间与抑郁症状的发作之间的关系：社区老年人纵向队列研究
Masanori Morikawa,Kenji Harada,Chiharu Nishijima et al.
Masanori Morikawa et al.
Background: Late-life depression is a major public-health concern. Although physical activity is protective, the longitudinal association of physical-activity timing on depressive-symptom onset in older adults remains unc...
Relationship between frailty and white matter hyperintensities: A systematic review and meta-analysis [0.03%]
衰弱与白质高密度血管关系的系统评价和meta分析
Xuzi Li,Anling Luo,Yiting Deng et al.
Xuzi Li et al.
Background: Frailty, common in aging, contributes to cognitive and motor decline. White matter hyperintensity (WMH), markers of cerebral small vessel disease, show similar effects. Although studies suggest an association ...