Targeting α7nAChR mitigates vascular aging and endothelial cell senescence through inhibiting oxidative stress and inflammation via α7nAChR/Nrf2/HO-1 signaling pathway [0.03%]
靶向α7nAChR通过α7nAChR/Nrf2/HO-1信号通路抑制氧化应激和炎症缓解血管衰老和内皮细胞衰老
Rui Ma,Yawen Zhang,Wencheng Wang et al.
Rui Ma et al.
Vascular aging is recognized as critical factor contributing to the onset and progression of cardiovascular diseases, which represent a leading cause of morbidity and mortality worldwide. The α7 nicotinic acetylcholine receptor (α7nAChR) ...
Association between oral health and physical frailty in community-dwelling older adults: A systematic review and meta-analysis [0.03%]
社区老年人口腔健康与身体衰弱的关联：系统评价和meta分析
Min Jung Ko,Seongwoo Seo,Jong Seob So et al.
Min Jung Ko et al.
Objective: Oral health and function are increasingly recognized as important determinants of overall health in the older population. This systematic review aimed to synthesize current pieces of evidences on how various or...
Engagement in cognitive activities and risk of loneliness: A longitudinal study among Japanese older adults [0.03%]
认知活动参与和孤独风险：一项关于日本老年人的纵向研究
Fumio Sakimoto,Takehiko Doi,Sho Nakakubo et al.
Fumio Sakimoto et al.
Background: Loneliness is a growing public health concern due to its association with adverse health outcomes in older adults. Research on the relationship between participation in cognitive activities and the alleviation...
Meaning in life and Parkinson's disease: Evidence from a 17-year study across 14 countries [0.03%]
生命的意义与帕金森病：来自14个国家17年的证据研究
Selin Karakose,Antonio Terracciano,Martina Luchetti et al.
Selin Karakose et al.
Background: Meaning in life is associated consistently with a reduced risk of incident Alzheimer's disease and related dementias. It also changes across the disease continuum. Less work has examined the association betwee...
Environmental chemical factors associated with human biological age acceleration: an interpretable machine learning study [0.03%]
与人类生物学年龄加速相关的环境化学因素：一种可解释的机器学习研究
Jian Xu,Zexin Zhu,Bo Dai et al.
Jian Xu et al.
This study utilized an interpretable machine learning (ML) framework to analyze data from 1693 adults in the 2015-2016 National Health and Nutrition Examination Survey (NHANES), investigating the association between 78 environmental chemica...
Liang-Kung Chen
Liang-Kung Chen
The effectiveness of artificial agents on loneliness reduction in older adults: a systematic review and meta-analysis [0.03%]
孤独减少的老年群体中人工代理有效性的系统评价和元分析
Zhengke Fu,Mengsi Yan,Xuefeng Han et al.
Zhengke Fu et al.
This meta-analysis reviewed studies comparing loneliness of older adults receiving artificial agent interventions with those not receiving them, to evaluate this treatment's efficacy in alleviating loneliness and other mental health problem...
The effects of Oligo-Fucoidan on muscle function in community-dwelling older adults: A double-blind, randomized, placebo-controlled trial [0.03%]
寡岩藻糖基壳聚糖对社区居住老年人肌肉功能的影响：一项双盲随机安慰剂对照试验
Yun-Ching Chang,Hung-Wen Liu,Tsung-Jen Hsieh et al.
Yun-Ching Chang et al.
Background: Sarcopenia, characterized by age-related loss of muscle mass and function, presents a growing public health concern in aging populations. While resistance training remains the gold standard for management, alt...
The effect of leisure-time physical activities on bone mineral density in postmenopausal women: Systematic review and meta-analysis [0.03%]
绝经后妇女休闲时间进行身体活动对骨密度影响的系统评价和 meta 分析
Anıl Siyahtaş,Elif Ünlügedik Sayın,Döndü Kurnaz
Anıl Siyahtaş
The aim of this systematic review and meta-analysis was to evaluate the impact of leisure-time physical activity (LTPA) on bone mineral density (BMD) in postmenopausal women. The protocol was developed according to PRISMA guidelines and reg...
Effects of dual-task prioritization training on dual-task walking in older people: A single-blinded randomized controlled trial [0.03%]
优先化双任务训练对老年人双任务行走的影响：单盲随机对照试验
Wei-Chen Chen,Yea-Ru Yang,Ching-Ya Chiu et al.
Wei-Chen Chen et al.
Objective: Dual-task walking (DTW) performance is commonly reduced in older adults and is associated with a higher risk of falls. While dual-task deficits have been documented, it remains unclear how different task priori...