Reframing sarcopenia: the AWGS 2025 paradigm shift from disease to muscle health [0.03%]
重构 sarcopenia：AWGS 2025 年范式从疾病向肌肉健康转变
Liang-Kung Chen
Liang-Kung Chen
Association between obesity and the transitions of frailty based on multi-state Markov model: A prospective study [0.03%]
基于多状态马尔可夫模型的肥胖与衰弱转变的关系：一项前瞻性研究
Bosen Lv,Xiaohui Li,Qianning Lu et al.
Bosen Lv et al.
Background: New evidence has revealed the dynamic transition characteristics of frailty. However, the potential differences in the effects of different types of obesity on the transition of frailty remain unclear. This pr...
Nutritional status and frailty in rheumatoid arthritis: A multicenter observational study (T-FLAG) [0.03%]
类风湿性关节炎的营养状况和脆弱性：一项多中心观察研究(T-FLAG)
Mochihito Suzuki,Shuji Asai,Yoshifumi Ohashi et al.
Mochihito Suzuki et al.
Objective: Frailty is a relevant clinical issue in rheumatoid arthritis (RA) patients, particularly as the population ages. Malnutrition, decreased physical function, and a loss of social connections are key contributors ...
Association between changes in social isolation status and frailty among older adults [0.03%]
社会孤立状态变化与老年人脆弱性之间的关系
Cho Rong Kim,Jisu Ko,Min Jin Ha et al.
Cho Rong Kim et al.
Introduction: Considering social isolation in approaches to frailty is important for the early detection of health problems in older adults and the development of appropriate intervention strategies. This study aims to in...
An overview of care coordination elements for older adults with long-term care needs: A narrative review [0.03%]
长期照护需求的老年人护理协调要素综述：叙述性回顾
Natasha Grande de França,Philipe de Souto Barreto,Hyobum Jang et al.
Natasha Grande de França et al.
Aims: Care coordination is crucial in long-term care (LTC) as it contributes to patient-centered, high-value, and high-quality care. This review presents an overview of how care coordination for older adults with long-ter...
Exercise upregulates Mitsugumin 53 and ameliorates behavioral deficits and mitochondrial biogenesis in a sporadic Alzheimer's disease model in rats [0.03%]
运动通过上调Mitsugumin 53改善老年痴呆模型小鼠的行为异常和线粒体生物合成
Muaz Belviranlı,Nilsel Okudan,Tuğba Sezer
Muaz Belviranlı
Chronic physical exercise is a promising non-pharmacological strategy to mitigate the progression of Alzheimer's disease (AD), yet the underlying molecular mechanisms remain incompletely understood. This study investigated the effects of ch...
Effects of branched-chain amino acid-rich nutritional supplements combined with resistance training on body composition and body function in older patients with sarcopenia [0.03%]
富含支链氨基酸的营养补充剂结合抗阻训练对肌少症老年人身体组成和身体功能的影响
Haoran Li,Runfa Zhang,Yongye Ma et al.
Haoran Li et al.
Background: Sarcopenia impairs self-care ability in older adults. While branched-chain amino acids (BCAAs)/leucine enhance muscle protein synthesis and resistance training promotes muscle growth, the combined effect on sa...
Heterogeneity in the associations of community gathering place participation with healthy ageing [0.03%]
社区聚集场所参与与健康老龄化相关性的异质性分析
Kazushige Ide,Kenjiro Kawaguchi,Ryota Watanabe et al.
Kazushige Ide et al.
Background: Extending healthy life expectancy is a critical policy priority in aging societies worldwide. In Japan, community gathering places (CGPs) for older adults, which are resident-led group activities conducted in ...
SGLT2 inhibitors versus DPP-4 inhibitors and dementia risk in type 2 diabetes: A meta-analysis of cohort studies [0.03%]
与DPP-4抑制剂相比，SGLT2抑制剂与2型糖尿病患者的痴呆风险：队列研究的meta分析
Zhaoshuang Zhong,Shijie Zhao,Wei He et al.
Zhaoshuang Zhong et al.
Background: Sodium-glucose cotransporter 2 (SGLT2) inhibitors have shown neuroprotective potential. This meta-analysis aimed to compare the effects of SGLT2 inhibitors and dipeptidyl peptidase-4 (DPP-4) inhibitors on deme...
Causal association between sleep disorders and delirium: A bidirectional mendelian randomization analysis for clinical practice [0.03%]
睡眠障碍和谵妄之间的因果关系：临床实践的双向孟德尔随机化分析
Wenxiu Niu,Jingjing Zhang,Xuhong Lan et al.
Wenxiu Niu et al.
Background: Numerous studies have identified a correlation between sleep disorders and delirium; however, the causal relationship remains ambiguous. This bidirectional two-sample Mendelian randomization (MR) study, combin...