Frère Noémie,Chelbi Lydia,Mathé Louise et al.
Frère Noémie et al.
Background: In vitro models are crucial for exploring cellular and molecular mechanisms underlying central nervous system (CNS) development and function. While long-term neuron-glia cultures have been well established in ...
NERV: A comprehensive framework for rapid, reproducible, and hardware-synchronized neuroscience experiment design and execution [0.03%]
NERV：一种用于快速、可重复的神经科学实验设计与执行的全面框架和硬件同步机制
Kyle Coutray,Christos Constantinidis
Kyle Coutray
Background: Behavioral neuroscience experiments require precise stimulus control, millisecond timing, hardware integration, and robust data provenance. The growing use of 3D environments and multimodal recordings increase...
Propagation Mapping using Iterative Independent Component Analysis for Seizure Onset Zone Localization in Temporal Lobe Epilepsy [0.03%]
基于迭代独立成分分析的癫痫发作起始区传播图映射方法研究
Bingyang Cai,Shize Jiang,Jiwei Li et al.
Bingyang Cai et al.
Background: Epilepsy affects approximately 70 million people worldwide, with a third of them being drug-resistant and requiring surgical intervention. Accurate localization of the seizure onset zone (SOZ) is crucial for e...
WormTracer: A precise method for worm posture analysis using temporal continuity [0.03%]
WormTracer:利用时间连续性进行精确线虫姿态分析的方法
Koyo Kuze,Ukyo T Tazawa,Karin Suwazono et al.
Koyo Kuze et al.
Background: Quantifying behavior is essential across diverse fields including ecology, ethology, neuroscience, and human science, where posture information provides particularly rich insights. Caenorhabditis elegans serve...
Automated ladder rung test for evaluating motor coordination in Parkinson's disease mouse models [0.03%]
帕金森病小鼠模型中评估运动协调的自动化梯级测试法
Peng Zhang,Wei Xu,Wei Jiang et al.
Peng Zhang et al.
Background: The ladder rung walking test assesses fine motor coordination in Parkinson's disease (PD) mouse models but relies on labor-intensive, subjective manual scoring, necessitating an automated, objective system. ...
Integrating spatial and temporal metrics in smartphone-based finger tapping test: Insights into motor performance dynamics [0.03%]
基于智能手机的指尖敲击测试中时空度量的整合：运动表现动态的洞察
Lucas de Sousa Miranda,Bruna Rafaela da Silva Sousa,Felipe André da Costa Brito et al.
Lucas de Sousa Miranda et al.
Background: The Finger Tapping Test (FTT) is a classical tool for assessing motor timing. While traditionally limited to temporal measures, smartphone-based versions enable simultaneous recording of both temporal and spat...
Empirical multi-scale thresholding for evoked neural activity denoising [0.03%]
数据驱动的多尺度阈值化事件相关电位信号去噪方法
Hamidreza Abbaspour,Harrison C Walker,Zachary T Irwin
Hamidreza Abbaspour
Background: Evoked potentials (EPs) are responses elicited by stimulation of the nervous system that serve as key biomarkers for assessing neural function, connectivity, and pathophysiology. Reliable EP extraction is chal...
Parkinson's disease diagnostic support based on voxel fusion of resting BOLD signals and DTI features using multimodal pretraining [0.03%]
基于多模态预训练的静息BOLD信号和DTI特征体素融合帕金森病诊断支持模型
Qingchuan Zhang,Zhenqiao Liu,Zexi Song et al.
Qingchuan Zhang et al.
Background: Parkinson's disease (PD) involves concurrent changes in brain functional activity and white matter microstructure, yet single-modality analyses often fail to capture these complex alterations. ...
A robust method for primary cerebellar culture and genetic manipulation of Purkinje cells from postnatal mice [0.03%]
一种用于从小鼠分离小脑原代培养和进行浦肯野细胞遗传学操作的稳健方法
Heiling Lu,Friederike Stephani,Myrna Aulia et al.
Heiling Lu et al.
Background: Primary cerebellar cultures are a powerful system for studying genes and pathways involved in development and disease. However, maintaining the survival of Purkinje cells in vitro remains challenging. These ne...
Comparing Methods for Mass Univariate Analyses of Human EEG: Empirical Data and Simulations [0.03%]
人脑EEG的大一元分析：实测数据与模拟研究
Anna-Lena Tebbe,Christian Panitz,Andreas Keil
Anna-Lena Tebbe
Background: Electroencephalography (EEG) is a widely used method for investigating human brain dynamics. However, EEG analyses are frequently conducted with limited a priori knowledge regarding locations or latencies of m...