Psychometric validation of the Tampa Scale of Kinesiophobia for Youth (TSK-7-Y): a brief measure of movement-related fear in youth with chronic pain [0.03%]
儿童和青少年慢性疼痛患者运动恐惧简明测量量表(TSK-7-Y)的度量验证研究
Robert C Gibler,Susmita Kashikar-Zuck,Mitchell Selhorst et al.
Robert C Gibler et al.
Fear of movement (FoM), or kinesiophobia, is associated with functional disability in individuals with chronic pain. The Tampa Scale of Kinesiophobia (TSK) is among the most widely used instruments for assessing FoM and has undergone severa...
Astrocyte coordinated remodelling of the dorsal horn endothelium and pain hypersensitivity [0.03%]
星形胶质细胞协调重塑脊髓背角血管内皮与痛觉过敏现象
Lydia D Hardowar,Ozde Cetinsoy,Jessica Bates et al.
Lydia D Hardowar et al.
Pain perception relies not only on sensory neurons but also on the interplay of a heterogeneous cell population, including endothelial cells, microglia, and astrocytes. Blood-spinal cord barrier dysfunction can alter nociceptive processing ...
Macrophage migration inhibitory factor (MIF) antagonist ISO-1 reduces neuroinflammation and neuropathic pain in a sex-dependent manner [0.03%]
巨噬细胞迁移抑制因子(MIF)拮抗剂ISO-1以性别依赖的方式降低神经炎症和神经病理性疼痛
Monica Pontearso,Anirban Bhattacharyya,Pavel Adamek et al.
Monica Pontearso et al.
Peripheral neuropathy is a global health concern that markedly impairs quality of life. Peripheral nerve injury triggers complex interactions between the immune and nervous systems, driving persistent neuroinflammation and neuropathic pain....
Income dynamics and risk of complex regional pain syndrome: a nationwide cohort study [0.03%]
收入变动与复杂性区域疼痛综合征风险的关系：全国队列研究
Sejong Jin,Kyungdo Han,Yong-Moon Mark Park et al.
Sejong Jin et al.
Complex regional pain syndrome (CRPS) is a chronic, treatment-refractory neuropathic disorder associated with substantial functional impairment and socioeconomic burden. Although socioeconomic conditions have been implicated in vulnerabilit...
International classification of diseases-11 chronic primary headache diagnoses: data-based adaptations of criteria for the pediatric population [0.03%]
国际疾病分类第十一次修订本慢性原发性头痛诊断：儿科人群分类标准数据基于适应性研究
Lisa-Marie Rau,Antonia Barke,Beatrice Korwisi et al.
Lisa-Marie Rau et al.
Many children present with chronic primary headache (CPH), yet classification within the International Classification of Diseases (ICD-11) is difficult, potentially impeding treatment pathways. The ICD-11 includes adult criteria, but it lac...
Psychosocial factors do not explain discrepancy between daily diary and one-week retrospective reports of pain [0.03%]
心理社会因素无法解释每日日记与一周回顾性疼痛报告之间的差异
Cecelia I Nelson,Chloe H Fisher,James Peugh et al.
Cecelia I Nelson et al.
Self-report is the gold standard for assessing pain intensity, although the method of acquiring pain reports may influence the ratings obtained. Retrospective reports of pain intensity are often found to be elevated relative to daily diary ...
Understanding opioid use for noncancer pain: a community pharmacy-based observational study of patient profiles and experiences [0.03%]
基于社区药房的观察性研究：阿片类药物用于非癌症疼痛患者的用药特征及体验分析
Els Mehuys,Sam Schelfout,Geert Crombez et al.
Els Mehuys et al.
Opioids are widely prescribed for noncancer pain, yet patient characteristics and experiences remain poorly understood. We conducted an observational study in community pharmacies (Belgium) to describe patient profiles, explore initiation a...
Pain prevalence and intensity in advanced pancreatic cancer: a nationwide cohort study [0.03%]
晚期胰腺癌疼痛的患病率和强度：一项全国队列研究
Aniek E Van Diepen,Merlijn U J E Graus,Simone Augustinus et al.
Aniek E Van Diepen et al.
Pain is a major concern in patients with advanced pancreatic cancer, significantly affecting quality of life, treatment tolerance, and end-of-life experience. However, data on its prevalence, course, and determinants remain limited, particu...
Neurobiology of the trigeminal ganglion in comparison to the dorsal root ganglion [0.03%]
三叉神经节与脊神经背根节的神经生物学比较研究
Shanchun Su,Minseok Kim,Wolfgang Liedtke et al.
Shanchun Su et al.
The trigeminal ganglion (TG) represents the craniofacial counterpart of the dorsal root ganglion (DRG) in the peripheral nervous system (PNS). TG and DRG are clusters of cell bodies of highly specialized sensory neurons, with TG neurons inn...
Peripheral kappa opioid receptors modulate cold hypersensitivity in a mouse model of chemotherapy-induced neuropathy [0.03%]
外周κ型阿片受体调节化疗诱发的神经病理性寒冷过敏反应
Manish K Madasu,Loc V Thang,Christian C Ohazurume et al.
Manish K Madasu et al.
Noxious cold sensation is commonly associated with peripheral neuropathies; however, there has been limited progress in understanding the mechanism. Here, we identify a novel role for peripherally expressed kappa opioid receptors [KORs] in ...