The African turquoise killifish (Nothobranchius furzeri): A model of age-related diseases and declining regenerative capability across multiple organs [0.03%]
非洲蓝彩燕鱼（诺托布拉奇乌斯-富泽里）：多器官衰老相关疾病和再生能力衰退的模型
Takayoshi Otsuka,Hideaki Matsui
Takayoshi Otsuka
African turquoise killifish (Nothobranchius furzeri) has emerged as a promising vertebrate model for aging research because of its unique characteristics. Its exceptionally short lifespan and rapid aging make it an ideal model for studying ...
Galectin-3-binding protein is a risk factor for Diabetes, Metabolic Syndrome, and Inflammation. Cross-sectional and Longitudinal Results from the InCHIANTI study [0.03%]
半乳糖凝集素-3结合蛋白是糖尿病、代谢综合征及炎症的危险因素。来自InCHIANTI研究横断面和前瞻性证据
Raffaello Pellegrino,David Perpetuini,Roberto Paganelli et al.
Raffaello Pellegrino et al.
Galectin-3-binding protein (Lgals3bp), a heavily glycosylated protein that plays a role in cell growth, inflammation, and cellular adhesion, has been associated with tumor development and more recently with carbohydrate and lipid metabolism...
Corrigendum to "Association of cytomegalovirus serostatus with ELOVL2 methylation: Implications for lipid metabolism, inflammation, DNA damage, and repair capacity in the MARK-AGE study population" [Mech. Ageing Dev. 225 (2025) 112043] [0.03%]
“巨细胞病毒血清状态与ELOVL2甲基化的关系：对MARK-AGE研究人群脂质代谢、炎症、DNA损伤和修复能力的影响”一文中表观遗传学部分的勘误[《机械老化与发展》第225卷(2025年)112043页]
Robertina Giacconi,Chiara Pirazzini,Maria Giulia Bacalini et al.
Robertina Giacconi et al.
Published Erratum
Mechanisms of ageing and development. 2025 Jun 26:112085. DOI:10.1016/j.mad.2025.112085 2025
Abhishek Chandra,Robert J Pignolo
Abhishek Chandra
Functional significance of extracellular vesicles as mediators of cardiometabolic and cardiorenal diseases upon aging [0.03%]
外泌体在衰老过程中介导心血管-代谢和心血管-肾脏疾病的功能意义
Wing Yan Chung,Sabrina Lam,Brooke Pernari et al.
Wing Yan Chung et al.
Aging increases the risk of cardiometabolic and cardiorenal disease and this is associated with cellular dysregulation including oxidative stress, chronic inflammation, insulin resistance and senescence. Extracellular vesicles (EV) facilita...
Targeting mitophagy in the heart: Exploring the therapeutic potential of MicroRNAs [0.03%]
靶向心肌细胞自噬：探索MicroRNA的治疗潜力
Amin Javadifar,Masoud Tahani,Sorousha Khayat et al.
Amin Javadifar et al.
Mitophagy, a selective form of autophagy, plays an indispensable role in preserving mitochondrial integrity by eliminating dysfunctional mitochondria, thereby sustaining cellular homeostasis. This process is particularly critical in cardiom...
Dietary ingredients inducing cellular senescence in animals and humans: A systematic review [0.03%]
动物和人类细胞衰老的饮食因素：系统性综述
Lihuan Guan,Kristina Zdantsevich,Elena Sandalova et al.
Lihuan Guan et al.
Background: Cellular senescence (CS) is a hallmark of ageing and age-related diseases. While dietary interventions are often explored to reduce CS, less is known about dietary ingredients that induce it. This study system...
Kalyani Pandya,Annabel Menendez,Mark G MacAskill et al.
Kalyani Pandya et al.
Age and sex exert profound influences on the heart, shaping its structure, function, and susceptibility to disease. Among the myriad of changes driven by age and sex, alterations in the extracellular matrix (ECM), particularly collagen infl...
The combination of GDF15, FGF21, sRAGE and NfL plasma levels can identify frailty in community-dwelling people across old age [0.03%]
GDF15、FGF21、sRAGE和NfL的血浆水平联合可用于识别社区居住老年人中的衰弱状态
Maria Conte,Federica Sevini,Giuseppe Conte et al.
Maria Conte et al.
Frailty is a complex medical condition characterized by decline in physiological functions and global health of older people, representing a strong risk factor for disability, hospitalization, and mortality. The identification of biomarkers...
Elena Carbone,Elisa Fabrizi,Roberto Rivabene et al.
Elena Carbone et al.
Studying aging and risk factors associated with chronic non-communicable diseases is increasingly relevant due to the progressive aging of the global population. Risk factors have focused on diet, physical exercise, cognitive activity, and ...