Increased virulence and decreased antimicrobial resistance in Klebsiella pneumoniae in Beijing since 2020: a retrospective molecular epidemiology study [0.03%]
北京肺炎克雷伯菌的毒力增加和耐药性降低（2020年以来的分子流行病学回顾性研究）
Lianping Zang,Beibei Liu,Zhenchao Wu et al.
Lianping Zang et al.
Endometrial microbiota-dimethylglycine-Treg cell axis affects endometrial receptivity in recurrent implantation failure [0.03%]
子宫微生态-二甲基甘氨酸-Treg细胞轴影响复发性着床失败患者的子宫内膜容受性
Fen-Ting Liu,Ping Zhou,Feng Deng et al.
Fen-Ting Liu et al.
Recurrent implantation failure (RIF) poses a substantial challenge in assisted reproductive technologies, causing serious psychological burden and economic pressure to patients with infertility. However, the pathogenesis of RIF remains uncl...
Targeting senescent cells in aged adipose tissue induced by ovarian cancer with the NF-κB inhibitor quercetin and resveratrol impedes the growth and metastasis of ovarian cancer [0.03%]
NF-κB抑制剂槲皮素和白藜芦醇靶向卵巢癌诱导的衰老脂肪组织中的衰老细胞可阻止卵巢癌的发生发展及转移
Jia Lv,Qiong Fan,Jianan Zhe et al.
Jia Lv et al.
As a lipophilic tumour, ovarian cancer (OC) preferentially metastasizes to adipose-rich environments including the omentum and the peritoneum. Current research regarding the OC microenvironment has focused primarily on tumour-associated imm...
Revisiting the role of dopamine, octopamine and serotonin in regulating sleep and locomotor activity [0.03%]
重新审视多巴胺、八臂底物和血清素在调节睡眠和运动活动中的作用
Sihui Jin,Can Gao,Mingze Ma et al.
Sihui Jin et al.
Repositioning ACLY in liver cancer: from metabolic enzyme to a regulator of antitumor immunity [0.03%]
ACLY在肝癌中的再定位：从代谢酶到抗肿瘤免疫调节因子
Shuhan Zhao,Jing Tang,Jun Xue
Shuhan Zhao
Zhe Lu,Junyuan Sun,Guorui Zhao et al.
Zhe Lu et al.
Schizophrenia is a multifaceted psychiatric disorder characterized by hallucinations, delusions, cognitive deficits, and social dysfunction. Its etiology involves a complex interplay of neurochemical, neurodevelopmental, genetic, and immune...
Hui-Hui Feng,Cheng-Xi Tan,Shao-Cheng Huang et al.
Hui-Hui Feng et al.
Why some flowers are so fragrant remains mysterious. The hypothesis of pollinator-mediated selection suggests that floral scent offers olfactory signals attracting pollen vectors, but it may be susceptible to pollen consumers. To explore th...
Cell type-specific contribution of low-density lipoprotein receptor to atherosclerosis [0.03%]
低密度脂蛋白受体在动脉粥样硬化发生中的细胞类型特异性作用
Wei-Hui Li,Yu-Liang Zhang,Ya-Fen Zhang et al.
Wei-Hui Li et al.
Elevated blood low-density lipoprotein (LDL) levels are a major risk factor for cardiovascular disease. Increasing LDL receptor (LDLR) expression effectively reduces blood LDL and serves as a key therapeutic strategy for preventing and trea...
Shifting from biotic to abiotic drivers of urban microbial multifunctionality under drought and rehydration [0.03%]
城市微生物多重功能在干旱和复水条件下从生物驱动向非生物驱动转变
Chenhong Peng,Anqi Sun,Xinyuan Li et al.
Chenhong Peng et al.
Climate change has intensified the frequency and severity of urban droughts, exposing urban green spaces to abrupt and extreme water shortage that disrupts plant-microbe interactions and microbial multifunctionality. Understanding how rhizo...
Global spread and evolution of KPC-2 and NDM-1-producing Gram-negative bacteria [0.03%]
KPC-2和NDM-1阳性革兰阴性杆菌的全球播散及进化演变
Meng Cai,Kaiwen Song,Chaoqun Yao et al.
Meng Cai et al.
The co-occurrence of KPC and NDM carbapenemases in Gram-negative bacteria presents a serious and expanding global health threat. This study characterized 338 KPC-2/NDM-1 dual-positive isolates from 23 countries, including 41 clinical strain...