SWI/SNF regulated HBV cccDNA transcription as a new target potential to functional cure [0.03%]
SWI/SNF调节HBV cccDNA转录作为功能性治愈的新靶点潜力
Kuanhui Xiang,Hui Zhuang
Kuanhui Xiang
Vesicles for cell crosstalk in bone: composition, function and application [0.03%]
骨细胞通讯的囊泡：组成、功能及应用
Chenhui Gu,Yiyu Chen,Pengyu Chen et al.
Chenhui Gu et al.
Vesicles, with closed membrane structures containing nucleic acids, proteins, lipids, and metabolites, play a vital role in cell crosstalk. And bone, the important center of cellular information exchange, is where abundant vesicle-based cel...
Dehydroepiandrosterone activates ADGRG2 to regulate chloride homeostasis and sperm motility via Gs-cAMP pathways [0.03%]
脱氢表雄酮通过Gs-cAMP通路激活ADGRG2调节氯离子稳态和精子运动能力
Dan Jiang,Ji-Fei Han,Xian-Zheng Guo et al.
Dan Jiang et al.
Dehydroepiandrosterone (DHEA), a steroid hormone critical to reproductive health, is widely used to improve outcomes in assisted reproductive technologies, though its molecular targets and mechanisms remain incompletely defined. In our prev...
USP7 protects histone H1.2 from proteasome-mediated degradation to facilitate DNA repair and pancreatic neuroendocrine neoplasms progression [0.03%]
USP7通过防止组蛋白H1.2被蛋白酶体降解来促进DNA修复和胰腺神经内分泌肿瘤的发展
Mujie Ye,Lin Xu,Ping Yu et al.
Mujie Ye et al.
Ubiquitin-specific protease 7 (USP7), a deubiquitinase, is involved in tumor progression. However, its roles in pancreatic neuroendocrine neoplasms (pNENs) remain unclear. The main objective of this study was therefore to investigate the mo...
mRNA compartmentalization directs pectin remodeling for meristem maintenance [0.03%]
编码细胞质mRNA的隔室化调控顶端分生组织形成的肽聚糖重塑
Xuanzhi Cheng,Xiaofeng Cao,Qikun Liu
Xuanzhi Cheng
Shu-Xin Cao,Xiang Luo,Yu Bai et al.
Shu-Xin Cao et al.
Genome-wide CRISPR/Cas9 knockout screen identifies host factors essential for bovine parainfluenza virus type 3 replication [0.03%]
基因组范围的CRISPR / Cas9敲除筛选鉴定出三型牛副流感病毒复制所必需的宿主因子
Jinyang Hao,Xiaoran Gao,Christine Light et al.
Jinyang Hao et al.
Bovine parainfluenza virus type 3 (BPIV3) is a leading cause of respiratory illness in cattle and a primary component of the bovine respiratory disease complex (BRDC), resulting in significant economic losses. Understanding the mechanisms o...
Fei Huang,Yanyuan Xiao
Fei Huang
Engineering high-fertility synthetic apomixis in hybrid rice via genome editing of MiMe and OspPLAIIκ [0.03%]
通过基因编辑实现杂交水稻高繁殖率的人工无融合生殖工程化设计
Chaolei Liu,Yuye Chen,Tingting Sun et al.
Chaolei Liu et al.
Dynamic trajectories of health-related quality of life during neoadjuvant chemotherapy in breast cancer: differential effects of anthracycline-taxane sequencing [0.03%]
乳腺癌新辅助化疗期间的生活质量动态轨迹：蒽环类-紫杉醇序贯的差异效应
Yuanyuan Wang,Ye Wang,Hao Yao et al.
Yuanyuan Wang et al.