Xiaowei Chen,Jingkai Xu,Xuejiao Song et al.
Xiaowei Chen et al.
Transposon targeting non-coding RNA transcription targets G/C-rich tracts and is facilitated by an intrinsically disordered protein in Tetrahymena [0.03%]
四膜虫转座子靶向非编码RNA转录针对G/C-富集轨迹，并由内在无序蛋白促进
Xia Cai,Yike Liu,Jialuo Li et al.
Xia Cai et al.
Tetrahymena is a well-established ciliate model organism, known for its nuclear dualism and unique mechanism for transposon defense, wherein transposons are kept within the highly heterochromatinized micronucleus (MIC), which is transcripti...
Exploring primate immune responses to SLA-I/II knockdown pig xenografts in humanized mice and rhesus monkeys [0.03%]
人源化小鼠和食蟹猴SLA-I/II敲低猪异种移植的免疫应答研究
Ming-Hui Fang,Hao Feng,Kai Xu et al.
Ming-Hui Fang et al.
Decoding the functional adaptation of animal echolocation: a global macroevolutionary analysis [0.03%]
动物回声定位的适应性进化机制及其全球宏观演化分析
Nan Wu,Jie Wang,Qian Wang et al.
Nan Wu et al.
Echolocating animals actively emit pulses of ultrasound and perceive acoustic reflections to determine the position of objects in dark, often three-dimensional spaces. Echolocation specificity thus depends on the properties of the calls emi...
Genomic insights into recurrent demographic collapses and recovery dynamics in Tibetan antelopes (Pantholops hodgsoni) [0.03%]
西藏盘羊(Pantholops hodgsoni)反复种群崩溃和恢复动力学的基因组洞察
Weimin Kuang,Hongfeng Zhang,Yingli Jiang et al.
Weimin Kuang et al.
Climate change and human activities since the late Pleistocene have profoundly impacted endemic species on the Qinghai-Tibetan Plateau. The Tibetan antelope (Pantholops hodgsonii), a keystone ungulate once heavily poached, experienced uncle...
The risk of pathogenic tick-borne viruses in Northeast Asia: a genomic and ecological modelling study [0.03%]
东北亚致病性蜱传病毒风险的基因组及生态建模研究
Moujian Guo,Hengcong Liu,Hong Zhou et al.
Moujian Guo et al.
The prevalence, epidemiological history and disease risk posed by pathogenic tick-borne viruses (TBVs) remain poorly understood in Northeast Asia. Here, over 12,000 ticks were collected from diverse ecological environments in Northeast Chin...
SREBP1-activated lipid metabolism drives ferroptosis and progression of clear cell renal cell carcinoma [0.03%]
SREBP1激活的脂质代谢驱动透明细胞肾细胞癌的铁死亡和进展
Bao Wang,Junpeng Fu,Jian Qian et al.
Bao Wang et al.
Clear cell renal cell carcinoma (ccRCC) exhibits aberrant lipid synthesis, yet how this metabolic reprogramming influences ferroptosis-a form of regulated cell death driven by lipid peroxidation-remains poorly understood. This study demonst...
Targeting SHOC2: a treatable therapeutic site in RAS(Q61) mutant cancers [0.03%]
靶向SHOC2：在RAS(Q61)突变癌症中的可治疗性治疗位点
Junliang Tang,Guoqing Ding,Jie Zhang
Junliang Tang
Approaching the perfection of natural enzymes: evolution of biomimetic catalytic systems [0.03%]
迈向天然酶完美的境界——仿生催化体系的进化
Sai Zhu,Zuoyi Liu,Cuiqi Liang et al.
Sai Zhu et al.
Weiqiong Feng,Zhenyang Xie,Hao Huang
Weiqiong Feng