Chandrababu Rejeeth,Tapas C Nag,Soundarapandian Kannan
Chandrababu Rejeeth
Cisplatin is used to treat a variety of tumors, but dose-limiting toxicities or intrinsic and acquired resistance limit its application in many types of cancer including breast. Cisplatin was attached to silica nanoparticles using aminoprop...
Mark Fletcher,Mohammad Biglarbegian,Suresh Neethirajan
Mark Fletcher
A nanorobot is defined as any smart structure which is capable of actuation, sensing, manipulation, intelligence, and swarm behavior at the nanoscale. In this study, we designed an intelligent system using fuzzy logic for diagnosis and trea...
Surface modification of cobalt oxide nanoparticles using phosphonomethyl iminodiacetic acid followed by folic acid: a biocompatible vehicle for targeted anticancer drug delivery [0.03%]
使用膦酸甲基咪唑二乙酸对氧化钴纳米粒子进行表面修饰,然后是叶酸:一种用于靶向抗癌药物传递的生物相容性载体
Sourav Chattopadhyay,Sandeep Kumar Dash,Totan Ghosh et al.
Sourav Chattopadhyay et al.
The aim of our study was to prepare multifunctional, biocompatible nanoparticles for site-specific drug delivery. Hydrophilic nanoparticles with surface-adorned amine, carboxyl, or aldehyde groups, to be later used for bio-conjugation, were...
Pharmacokinetics and biodistribution of negatively charged pectin nanoparticles encapsulating paclitaxel [0.03%]
包裹紫杉醇的带负电的果胶纳米粒的药代动力学和生物分布研究
Anita K Verma,A Kumar
Anita K Verma
Pectin, a naturally occurring biopolymer has been found to have increasing applications in the pharmaceutical and biotechnology industry. Sugars with their three-dimensional structures are important for many biological functions. We report ...
Ravi Geetha,Thirunavukkarasu Ashokkumar,Selvaraj Tamilselvan et al.
Ravi Geetha et al.
As the nano revolution unfolds, it is imperative to integrate nanoscience and medicine. The secret gleaned from nature have led to the generation of biogenic technologies for the fabrication of advanced nanomaterials. Present investigation ...
Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment [0.03%]
表面等离子体增强的Ag/CuS纳米复合材料用于癌症治疗
Chang Yang,Lun Ma,Xiaoju Zou et al.
Chang Yang et al.
Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are...
Fungus-mediated synthesis of silver nanoparticles and evaluation of antitumor activity [0.03%]
真菌介导的银纳米粒子的合成及其抗肿瘤活性评价
S M El-Sonbaty
S M El-Sonbaty
Silver nanoparticles (AgNPs) were biologically synthesized using aqueous extract of Agaricus bisporus fungi. Physicochemical analysis of silver nanoparticles revealed that they are of spherical shape ranged size of 8-20 nm, and their zeta p...
Encapsulation of exemestane in polycaprolactone nanoparticles: optimization, characterization, and release kinetics [0.03%]
聚ε-己内酯纳米粒对依美司坦的包裹:优化,表征和释放动力学
Abhinesh Kumar,Krutika Sawant
Abhinesh Kumar
This study was aimed at developing a polymeric drug delivery system for a steroidal aromatase inhibitor, exemestane (exe) intended for sustained targeted delivery of drug through intravenous route. Carboxylated polycaprolactone (cPCL) was s...
Antileukemic potential of PEGylated gold nanoparticle conjugated with protein toxin (NKCT1) isolated from Indian cobra (Naja kaouthia) venom [0.03%]
从印度眼镜蛇(Naja kaouthia)毒液中分离的连接蛋白毒素(NKCT1)的PEG修饰的金纳米粒的抗白血病潜能
Tanmoy Bhowmik,Partha Pratim Saha,Anjan Dasgupta et al.
Tanmoy Bhowmik et al.
Limited efficacy of current first-line treatment for leukemia calls attention for further development of efficient strategies. Recently, much attention has been given to nanoparticle-based drug delivery systems loaded with dual drugs to imp...
Active targeting of HER2-positive breast cancer cells by Herceptin-functionalized organically modified silica nanoparticles [0.03%]
赫赛汀功能化的有机改性硅纳米颗粒对HER2阳性乳腺癌细胞的主动靶向作用
Vahid Shirshahi,Fereshteh Shamsipour,Amir Hassan Zarnani et al.
Vahid Shirshahi et al.
Normal micelle microemulsion method was utilized for fabrication of organically modified silica (ORMOSIL) nanoparticles. The void and dye-doped nanoparticles were synthesized in nonpolar core of two different surfactants including Aerosol O...