M1 Macrophage-Engineered Vesicles Have Anti-Cancer Activity in Ovarian Cancer [0.03%]
M1型巨噬细胞来源外泌体对卵巢癌的治疗作用研究
Connie D Cao,J Robert McCorkle,Derek B Allison et al.
Connie D Cao et al.
Background: Ovarian cancer typically presents at an advanced stage, has a poor prognosis, and is a leading cause of cancer-related deaths in women. Extracellular vesicles (EVs) are cell membrane derived nanoparticles that...
Quercetin-Fe nanodots inhibit cervical cancer cell proliferation by targeting PCNA [0.03%]
檞皮素-铁纳米点通过靶向PCNA抑制宫颈癌细胞增殖
Youwei Zhou,Sheng Cheng,Lei Shu et al.
Youwei Zhou et al.
Objective: The targets and active components that affect the prognosis of cervical cancer remain unclear. Methods: Three microarray dat...
Generation of magnetic biohybrid microrobots based on MSC.sTRAIL for targeted stem cell delivery and treatment of cancer [0.03%]
基于MSCs.TRAIL生成磁性生物混合微机器人用于靶向干细胞递送及癌症治疗
Rebekah Anamarie Gundersen,Tianyuan Chu,Kiana Abolfathi et al.
Rebekah Anamarie Gundersen et al.
Background: Combining the power of magnetic guidance and the biological activities of stem cells transformed into biohybrid microrobots holds great promise for the treatment of several diseases including cancer. ...
Utilizing two-dimensional monolayer and three-dimensional spheroids to enhance radiotherapeutic potential by combining gold nanoparticles and docetaxel [0.03%]
利用二维单层和三维类器官球体结合金纳米粒子和多西他赛以增强放射治疗潜力
Kyle Bromma,Wayne Beckham,Devika B Chithrani
Kyle Bromma
Background: Much in vitro research on the applicability of gold nanoparticles (GNPs) in cancer treatment has been focused on two-dimensional (2D) monolayer models. To improve this, we explored the effect of the combinatio...
Dual enhancement in the radiosensitivity of prostate cancer through nanoparticles and chemotherapeutics [0.03%]
通过纳米颗粒和化疗药物双重增强前列腺癌的放射敏感性
Nolan Jackson,Iona Hill,Abdulaziz Alhussan et al.
Nolan Jackson et al.
Background: Radiotherapy (RT) is an essential component in the treatment regimens for many cancer patients. However, the dose escalation required to improve curative results is hindered due to the normal tissue toxicity t...
Nanoliposomal VEGF-R2 peptide vaccine acts as an effective therapeutic vaccine in a murine B16F10 model of melanoma [0.03%]
用于小鼠B16F10黑色素瘤模型的纳米脂质体VEGF-R2肽疫苗可作为有效的治疗性疫苗
Fatemeh Zahedipour,Parvin Zamani,Mohammad Mashreghi et al.
Fatemeh Zahedipour et al.
Background: The vascular endothelial growth factor receptor-2 (VEGFR-2) plays an important role in melanoma development and progression. Peptide vaccines have shown great potential in cancer immunotherapy by targeting VEG...
Monocytes reprogrammed by tumor microparticle vaccine inhibit tumorigenesis and tumor development [0.03%]
肿瘤微粒疫苗重编程的单核细胞可抑制肿瘤发生及发展
Weiwei Sun,Lili Dai,Yuqing Cao et al.
Weiwei Sun et al.
Tumor microparticles (T-MPs) are considered as a tumor vaccine candidate. Although some studies have analyzed the mechanism of T-MPs as tumor vaccine, we still lack understanding of how T-MPs stimulate a strong anti-tumor immune response. H...
Nanoparticles advanced from preclinical studies to clinical trials for lung cancer therapy [0.03%]
从临床前研究到临床试验：纳米颗粒在肺癌治疗中的应用进展
Yifan Liu,Wenxu Cheng,HongYi Xin et al.
Yifan Liu et al.
Lung cancer is the leading cause of cancer mortality. As a heterogeneous disease, it has different subtypes and various treatment modalities. In addition to conventional surgery, radiotherapy and chemotherapy, targeted therapy and immunothe...
Doxorubicin-loaded liposomes surface engineered with the matrix metalloproteinase-2 cleavable polyethylene glycol conjugate for cancer therapy [0.03%]
一种工程化表面载有丝裂霉素-2可裂解的聚乙二醇共轭物的多柔比星脂质体用于癌症治疗
Anis Askarizadeh,Mohammad Mashreghi,Elaheh Mirhadi et al.
Anis Askarizadeh et al.
Background: Colorectal cancer is one of the prominent leading causes of fatality worldwide. Despite recent advancements within the field of cancer therapy, the cure rates and long-term survivals of patients suffering from...
Radiolabeled nanomaterial for cancer diagnostics and therapeutics: principles and concepts [0.03%]
放射标记纳米材料在癌症诊断和治疗中的原理及概念研究
Muskan Goel,Yuri Mackeyev,Sunil Krishnan
Muskan Goel
In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora of applications in biology and medicine. A convergence of t...