Modulation of cytotoxic and genotoxic effects of nanoparticles in cancer cells by external magnetic field [0.03%]
外部磁场调节纳米颗粒在癌细胞中的细胞毒性和遗传毒性作用
Jyoti Shaw,Sufi O Raja,Anjan Kr Dasgupta
Jyoti Shaw
Magnetic nanoparticles are well known for anticancer activity by deregulating cellular functions. In the present study, cellular effects of low strength static magnetic field (SMF) were explored. How nanoparticles affect the cellular respon...
Effective cellular internalization of silica-coated CdSe quantum dots for high contrast cancer imaging and labelling applications [0.03%]
用于高对比度癌症成像和标记应用的二氧化硅包覆CdSe量子点的有效细胞内化
Muthunayagam Vibin,Ramachandran Vinayakan,Annie John et al.
Muthunayagam Vibin et al.
The possibility of developing novel contrast imaging agents for cancer cellular labelling and fluorescence imaging applications were explored using silica-coated cadmium selenide (CdSe) quantum dots (QDs). The time dependent cellular intern...
AGuIX nanoparticles as a promising platform for image-guided radiation therapy [0.03%]
AGuIX纳米颗粒在影像引导放疗中的应用前景研究
Alexandre Detappe,Sijumon Kunjachan,Joerg Rottmann et al.
Alexandre Detappe et al.
AGuIX are gadolinium-based nanoparticles developed mainly for imaging due to their MR contrast properties. They also have a potential role in radiation therapy as a radiosensitizer. We used MRI to quantify the uptake of AGuIX in pancreatic ...
Size-dependent cellular toxicity and uptake of commercial colloidal gold nanoparticles in DU-145 cells [0.03%]
杜-145细胞中市售胶体金纳米颗粒的尺寸依赖性细胞毒性和吸收机制研究
Pallavi Vedantam,George Huang,T R Jeremy Tzeng
Pallavi Vedantam
Urinary tract infection (UTI) is a predominant condition in prostate cancer patients. Escherichia coli ORN178 (EC-178) is the uropathogen that causes recurrent infection by binding specifically to adhesins of prostate cancer cells (DU-145 c...
Development of in vitro gene delivery system using ORMOSIL nanoparticle: Analysis of p53 gene expression in cultured breast cancer cell (MCF-7) [0.03%]
基于ORMOSIL纳米粒的体外基因转染体系的建立及p53基因在乳腺癌细胞系(MCF-7)中表达的研究
Chandrababu Rejeeth,Soundarapandian Kannan,Krishnasamy Muthuchelian
Chandrababu Rejeeth
This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as an efficient in vitro gene delivery system in the recent years. Based on that prime objective, the present study addresses the possible ways t...
Facile synthesis of biocompatible gold nanoparticles from Vites vinefera and its cellular internalization against HBL-100 cells [0.03%]
一种合成生物相容性金纳米颗粒及其对抗HBL-100细胞的简便方法
Kanchana Amarnath,Nina Liza Mathew,Jayshree Nellore et al.
Kanchana Amarnath et al.
The remarkable health benefits of the chemical cocktails occluded within Vites vinefera (grapes) have been broadly used as dietary supplements and as natural pharmaceuticals in the treatment of various diseases including human cancer. Curre...
Investigating the specific uptake of EGF-conjugated nanoparticles in lung cancer cells using fluorescence imaging [0.03%]
荧光成像研究EGF结合纳米颗粒在肺癌细胞中的特异性摄取
Honglin Jin,Jonathan F Lovell,Juan Chen et al.
Honglin Jin et al.
Targeted nanoparticles have the potential to deliver a large drug payload specifically to cancer cells. Targeting requires that a ligand on the nanoparticle surface interact with a specific membrane receptor on target cells. However, the co...
Grace Cole,Joanne McCaffrey,Ahlam A Ali et al.
Grace Cole et al.
While locally confined prostate cancer is associated with a low five year mortality rate, advanced or metastatic disease remains a major challenge for healthcare professionals to treat and is usually terminal. As such, there is a need for t...
Gemcitabine-loaded PLGA-PEG immunonanoparticles for targeted chemotherapy of pancreatic cancer [0.03%]
用于胰腺癌靶向化疗的Gemcitabine载PLGA-PEG免疫纳米粒
Sahil Aggarwal,Swati Gupta,Dilrose Pabla et al.
Sahil Aggarwal et al.
The aim of the present study was the direct covalent coupling of the epidermal growth factor receptor (EGFR)-specific monoclonal antibody (mAb) to the surface of poly(lactide)-co-glycolide (PLGA)-polyethylene glycol (PEG) nanoparticles in o...
Biosynthesis of silver nanoparticles using the extract of Alternanthera sessilis-antiproliferative effect against prostate cancer cells [0.03%]
使用Alternanthera sessilis提取物合成银纳米粒子及其对前列腺癌细胞的抗增殖作用
M Jannathul Firdhouse,P Lalitha
M Jannathul Firdhouse
Green synthesis of silver nanoparticles was carried out using the aqueous extract of Alternanthera sessilis under various experimental conditions. The aqueous extract of Alternanthera sessilis showed significant potential for the quick redu...