Fred Currell,Steven Curley,Željka Krpetić et al.
Fred Currell et al.
Cancer resistance to treatment and antiresistance tools offered by multimodal multifunctional nanoparticles [0.03%]
用于治疗耐药癌症的多功能多模态纳米颗粒抗菌工具
Eudald Casals,Muriel F Gusta,Macarena Cobaleda-Siles et al.
Eudald Casals et al.
Chemotherapeutic agents have limited efficacy and resistance to them limits today and will limit tomorrow our capabilities of cure. Resistance to treatment with anticancer drugs results from a variety of factors including individual variati...
The application of titanium dioxide, zinc oxide, fullerene, and graphene nanoparticles in photodynamic therapy [0.03%]
用于光动力治疗的二氧化钛、氧化锌、富勒烯和石墨烯纳米粒子的应用
Zahraa Youssef,Régis Vanderesse,Ludovic Colombeau et al.
Zahraa Youssef et al.
Nanoparticles (NPs) have been shown to have good ability to improve the targeting and delivery of therapeutics. In the field of photodynamic therapy (PDT), this targeting advantage of NPs could help ensure drug delivery at specific sites. A...
Sha Li,Erika Porcel,Hynd Remita et al.
Sha Li et al.
Backgroud: Small metallic nanoparticles are proposed as potential nanodrugs to optimize the performances of radiotherapy. This strategy, based on the enrichment of tumours with nanoparticles to amplify radiation effects i...
An overview of current practice in external beam radiation oncology with consideration to potential benefits and challenges for nanotechnology [0.03%]
外照射放射肿瘤学的现状及纳米技术的前景与挑战概述
Raymond B King,Stephen J McMahon,Wendy B Hyland et al.
Raymond B King et al.
Over the past two decades, there has been a significant evolution in the technologies and techniques employed within the radiation oncology environment. Over the same period, extensive research into the use of nanotechnology in medicine has...
Soraia Rosa,Chris Connolly,Giuseppe Schettino et al.
Soraia Rosa et al.
There has been growing interest in the use of nanomaterials for a range of biomedical applications over the last number of years. In particular, gold nanoparticles (GNPs) possess a number of unique properties that make them ideal candidates...
A local effect model-based interpolation framework for experimental nanoparticle radiosensitisation data [0.03%]
基于局部效应模型的实验纳米颗粒放射增敏数据插值框架
Jeremy M C Brown,Fred J Currell
Jeremy M C Brown
A local effect model (LEM)-based framework capable of interpolating nanoparticle-enhanced photon-irradiated clonogenic cell survival fraction measurements as a function of nanoparticle concentration was developed and experimentally benchmar...
Yu Mi,Zhiying Shao,Johnny Vang et al.
Yu Mi et al.
Radiotherapy has been an integral treatment modality for cancer. The field arose from and progressed through innovations in physics, engineering, and biology. The evolution of radiation oncology will rely on the continued adoption of advanc...
Harry W Clifford,Amy P Cassidy,Courtney Vaughn et al.
Harry W Clifford et al.
Background: Cancer is first and foremost a disease of the genome. Specific genetic signatures within a tumour are prognostic of disease outcome, reflect subclonal architecture and intratumour heterogeneity, inform treatme...
Synthetic nanoparticles for delivery of radioisotopes and radiosensitizers in cancer therapy [0.03%]
癌症治疗用放射同位素和放射增敏剂的合成纳米递送载体
Jun Zhao,Min Zhou,Chun Li
Jun Zhao
Radiotherapy has been, and will continue to be, a critical modality to treat cancer. Since the discovery of radiation-induced cytotoxicity in the late 19th century, both external and internal radiation sources have provided tremendous benef...