Lindsey A Bennie,Helen O McCarthy,Jonathan A Coulter
Lindsey A Bennie
Nanoparticles can be used as drug carriers, contrast agents and radiosensitisers for the treatment of cancer. Nanoparticles can either passively accumulate within tumour sites, or be conjugated with targeting ligands to actively enable tumo...
Towards photon radiotherapy treatment planning with high Z nanoparticle radiosensitisation agents: the Relative Biological Effective Dose (RBED) framework [0.03%]
基于高Z纳米颗粒放射增敏剂的光子放疗治疗计划：相对生物有效剂量(RBED)框架
Jeremy M C Brown,Gerard G Hanna,Nathanael Lampe et al.
Jeremy M C Brown et al.
A novel treatment planning framework, the Relative Biological Effective Dose (RBED), for high Z nanoparticle (NP)-enhanced photon radiotherapy is developed and tested in silico for the medical exemplar of neoadjuvant (preoperative) breast c...
C60 fullerene and its nanocomplexes with anticancer drugs modulate circulating phagocyte functions and dramatically increase ROS generation in transformed monocytes [0.03%]
C60富勒烯及其与抗肿瘤药物的纳米复合物可调节循环白细胞的功能并显着增加单核细胞转化产物中的ROS生成
Larysa M Skivka,Svitlana V Prylutska,Mariia P Rudyk et al.
Larysa M Skivka et al.
Background: C60 fullerene-based nanoformulations are proposed to have a direct toxic effect on tumor cells. Previous investigations demonstrated that C60 fullerene used alone or being conjugated with chemotherapeutic agen...
Magnetic hyperthermia of breast cancer cells and MRI relaxometry with dendrimer-coated iron-oxide nanoparticles [0.03%]
磁性海藻酸钠纳米颗粒的制备及其体外超小效应研究
Marzieh Salimi,Saeed Sarkar,Reza Saber et al.
Marzieh Salimi et al.
Background: Recently, some studies have focused on dendrimer nanopolymers as a magnetic resonance imaging (MRI) contrast agent or a vehicle for gene and drug delivery. Considering the suitable properties of these material...
Chiyi Xiong,Wei Lu,Min Zhou et al.
Chiyi Xiong et al.
Background: Hollow gold nanoparticles (HGNPs) exposed to near-infrared (NIR) light yield photothermal effects that can trigger a variety of biological effects for potential biomedical applications. However, the mechanism ...
Gene therapy with RALA/iNOS composite nanoparticles significantly enhances survival in a model of metastatic prostate cancer [0.03%]
携带RALA/iNOS复合纳米颗粒的基因治疗在转移性前列腺癌模型中显著提高生存率
Cian M McCrudden,John W McBride,Joanne McCaffrey et al.
Cian M McCrudden et al.
Background: Recent approvals of gene therapies by the FDA and the EMA for treatment of inherited disorders have further opened the door for assessment of nucleic acid pharmaceuticals for clinical usage. Arising from the p...
Antiangiogenic and antiapoptotic effects of green-synthesized zinc oxide nanoparticles using Sargassum muticum algae extraction [0.03%]
使用孔松藻提取物绿色合成的氧化锌纳米粒子的抗血管生成和抗凋亡作用
Zahra Sanaeimehr,Iraj Javadi,Farideh Namvar
Zahra Sanaeimehr
Background: Algae are one of the natural materials used to green synthesis of nanoparticles. This method leads to minimize the toxicity of the chemical materials used to nanoparticle synthesis. ...
Important parameters for optimized metal nanoparticles-aided electromagnetic field (EMF) effect on cancer [0.03%]
优化金属纳米颗粒增强电磁场(EMF)效应抗肿瘤的重要参数分析
Lawrence Ochoo,Charles Migwi,John Okumu
Lawrence Ochoo
Background: A number of experimental research findings for the metal nanoparticles (NPs)-mediated EMF photothermal therapy of cancer cells show an intriguing trend of the NPs' size-dependent efficacy. This is a phenomenon...
Electrochemical and optical biosensors for early-stage cancer diagnosis by using graphene and graphene oxide [0.03%]
基于石墨烯和氧化石墨烯的电化学生物传感器和光学生物传感器的早期癌症诊断方法
Aditya Balaji,Jin Zhang
Aditya Balaji
Conventional instruments for cancer diagnosis including magnetic resonance imaging, computed tomography scan, are expensive and require long-waiting time, whilst the outcomes have not approached to the successful early-stage diagnosis yet. ...
Sandrine Lacombe,Erika Porcel,Emanuele Scifoni
Sandrine Lacombe
Cancer radiation therapy with charged particle beams, called particle therapy, is a new therapeutic treatment presenting major advantages when compared to conventional radiotherapy. Because ions have specific ballistic properties and a high...