Thermo-optical analysis and selection of the properties of absorbing nanoparticles for laser applications in cancer nanotechnology [0.03%]
用于癌症纳米技术激光应用的吸收型纳米粒子特性选择的热光分析
Victor K Pustovalov,L G Astafyeva,E Galanzha et al.
Victor K Pustovalov et al.
Applications of nanoparticles (NPs) as photothermal (PT) and photoacoustic (PA) labels and agents for diagnosis and therapy of cancer and other diseases in laser medicine are fast growing areas of research. Many potential benefits include p...
Evaluating the potential of polymer nanoparticles for oral delivery of paclitaxel in drug-resistant cancer [0.03%]
评估聚合物纳米颗粒口服传递紫杉醇在药物抵抗癌症中的潜力
V Bhardwaj,J A Plumb,J Cassidy et al.
V Bhardwaj et al.
The present study was designed to explore the ability of polymeric nanoparticles to restore drug sensitivity to P-glycoprotein over-expressing cancer cells. A multidrug-resistant cell line 2780 AD and its sensitive parent cell line A2780 we...
Folic acid-CdTe quantum dot conjugates and their applications for cancer cell targeting [0.03%]
叶酸-Cds量子点偶联物及其在癌症细胞定位中的应用
Preethi Suriamoorthy,Xing Zhang,Guiyang Hao et al.
Preethi Suriamoorthy et al.
In this study, we report the preparation, luminescence, and targeting properties of folic acid-CdTe quantum dot conjugates. Water-soluble CdTe quantum dots were synthesized and conjugated with folic acid using 1-ethyl-3-(3-dimethylaminoprop...
Micro- and nanotechnology approaches for capturing circulating tumor cells [0.03%]
用于捕捉循环肿瘤细胞的微纳技术方法
Balaji Panchapakesan,Robert Caprara,Vanessa Velasco et al.
Balaji Panchapakesan et al.
Circulating tumor cells (CTC) are cells that have detached from primary tumors and circulate in the bloodstream where they are carried to other organs, leading to seeding of new tumors and metastases. CTC have been known to exist in the blo...
Contact-mediated intracellular delivery of hydrophobic drugs from polymeric nanoparticles [0.03%]
聚合物纳米颗粒介导的疏水药物细胞内传递接触方法
Sofie Snipstad,Sara Westrøm,Yrr Mørch et al.
Sofie Snipstad et al.
Encapsulation of drugs in nanoparticles can enhance the accumulation of drugs in tumours, reduce toxicity toward healthy tissue, and improve pharmacokinetics compared to administration of free drug. To achieve efficient delivery and release...
Exploratory use of docetaxel loaded acid-prepared mesoporous spheres for the treatment of malignant melanoma [0.03%]
载多西他赛酸合成介孔球的制备及体内外抗黑色素瘤效果研究
Sameer Kaiser,Maximilian B MacPherson,Ted A James et al.
Sameer Kaiser et al.
Introduction: Five year survival for metastatic melanoma (MM) is very low at
Cell localisation of gadolinium-based nanoparticles and related radiosensitising efficacy in glioblastoma cells [0.03%]
基于钆的纳米颗粒在胶质母细胞瘤细胞中的亚细胞定位及其相关的放射增敏作用
Lenka Stefančíková,Erika Porcel,Pierre Eustache et al.
Lenka Stefančíková et al.
Recently, the addition of nanoparticles (NPs) has been proposed as a new strategy to enhance the effect of radiotherapy particularly in the treatment of aggressive tumors such as glioblastoma. The physical processes involved in radiosensiti...
Could nanoparticle corona characterization help for biological consequence prediction? [0.03%]
纳米颗粒冠状体的表征有助于其生物效应预测吗？
Emilie Brun,Cécile Sicard-Roselli
Emilie Brun
As soon as they enter a biological medium (cell culture medium for in vitro, blood or plasma for in vivo studies), nanoparticles, in most cases, see their surface covered by biomolecules, especially proteins. What the cells see is thus not ...
The role of mitochondrial function in gold nanoparticle mediated radiosensitisation [0.03%]
线粒体功能在金纳米颗粒介导的放射增敏中的作用
Laura E Taggart,Stephen J McMahon,Fred J Currell et al.
Laura E Taggart et al.
Gold nanoparticles (GNPs), have been demonstrated as effective preclinical radiosensitising agents in a range of cell models and radiation sources. These studies have also highlighted difficulty in predicted cellular radiobiological respons...
Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse [0.03%]
利用细胞特洛伊木马将纳米颗粒递送到乳腺癌脑转移灶中
Mi-Ran Choi,Rizia Bardhan,Katie J Stanton-Maxey et al.
Mi-Ran Choi et al.
As systemic cancer therapies improve and are able to control metastatic disease outside the central nervous system, the brain is increasingly the first site of relapse. The blood-brain barrier (BBB) represents a major challenge to the deliv...