Dual effects of progesterone on HaCaT human keratinocytes: apoptosis induction and suppression of oxidative stress and TLR2 expression with potential implications for hyperplastic skin disorders [0.03%]
孕酮对HaCaT人角质形成细胞的双重作用：诱导凋亡和抑制氧化应激及TLR2表达在增生性皮肤病中的潜在影响
Seyedeh Sindokht Hosseini,Elham Akbari,Somaye Karimi et al.
Seyedeh Sindokht Hosseini et al.
Objectives: Hyperplastic skin disorders such as psoriasis are characterized by excessive keratinocyte proliferation, impaired apoptosis, oxidative stress, and sustained activation of innate immune pathways. While conventi...
Comprehensive analysis of HLA-G expression, hormonal profiles, and inflammatory markers in women with recurrent pregnancy loss [0.03%]
HLA-G表达、激素水平和炎症标志物在复发性流产女性中的综合分析
Simi Nadarajan,Arumugam Suresh,Dinesh Roy Divakaran et al.
Simi Nadarajan et al.
Objectives: This study aimed to investigate the role of Human Leukocyte Antigen-G (HLA-G) gene expression, inflammatory cytokines, and hormonal profiles in the pathogenesis of recurrent pregnancy loss (RPL) and to assess ...
Association of APOE gene expression with thyroid dysfunction, inflammation, and nitrosative stress in cardiometabolic syndrome: a case-control study [0.03%]
APOE基因表达与甲状腺功能减退、炎症和亚硝化应激在心血管代谢综合症中的关联：一项病例对照研究
Thahira Abdulla,Thirumal Kumar D,Jaiganesh Inbanathan et al.
Thahira Abdulla et al.
Objectives: This study aimed to examine the association of thyroid-stimulating hormone (TSH), interleukin-6 (IL-6), and 3-nitrotyrosine (3-NT) with ApoE gene expression and to evaluate their diagnostic utility in CMS. ...
Estrogen receptor signaling without estrogen: molecular insights into hormone resistance [0.03%]
无雌激素的雌激素受体信号通路：对抗荷尔蒙治疗抵抗的分子新知
Gunvanti Rathod,Pragnesh Parmar
Gunvanti Rathod
Objectives: Estrogen receptor alpha (ERα) is thought to be a ligand-dependent transcription factor. Increasing number of data suggest that ERα is able to retain its transcriptional activity without stimulation by estrog...
Association of vitamin D, HbA1c, and pain severity in T2DM patients with peripheral neuropathy [0.03%]
维生素D、HBA1C与T2DM周围神经病变患者疼痛程度的相关性分析
Alan Bapeer Hassan,Ali Hussein Ahmad Al Dosky,Deldar Morad Abdulah
Alan Bapeer Hassan
Objectives: To evaluate the association of vitamin D linked with HbA1c level and pain severity in T2DM patients with peripheral neuropathy. Methods: ...
Metabolic burden is independently and linearly associated with lower testosterone levels: evidence from NHANES [0.03%]
代谢负担与较低的睾酮水平独立且线性相关：来自NHANES的证据
Yavuz Güler
Yavuz Güler
Objectives: Testosterone deficiency and metabolic dysfunction frequently coexist in aging men; however, whether metabolic impairment is associated with a progressive decline in testosterone across the metabolic spectrum r...
Effect of Vitamin B12 supplementation on glycemic control, albuminuria and peripheral neuropathy in diabetes mellitus patients - a cross sectional study [0.03%]
维生素B12补充对糖尿病患者血糖、尿白蛋白及外周神经病变的影响-一项横断面研究
Rahul Kumar,Pinky Garg,Mansi Modi et al.
Rahul Kumar et al.
Objectives: Type 2 Diabetes Mellitus (T2DM) is a global health challenge linked to microvascular complications like neuropathy and nephropathy. Metformin, first-line therapy, is associated with Vitamin B12 deficiency, pot...
Ahmad Fazilat,Fatemeh Mortazavi Moghadam,Salomeh Roshani et al.
Ahmad Fazilat et al.
One of the most common treatments used for cancer is chemotherapy. Different drugs are used in chemotherapy depending on the type of cancer. In this regard, one of the most basic problems in chemotherapy is drug resistance, in which people ...
Indications that the direct effects of supplemented vitamin D3 on the adrenal cortex are of secondary importance for glucocorticoid output [0.03%]
补充维生素D3对肾上腺皮质的直接影响对于糖皮质激素分泌的重要性较小的迹象
Vladimir Ajdžanović,Branka Šošić-Jurjević,Marko Miler et al.
Vladimir Ajdžanović et al.
Vitamin D3 supplementation is beneficial for various symptoms of aging and may stabilize hypothalamic-pituitary-adrenal (HPA) axis function. Systemic and local metabolic activation of vitamin D3 are essential for its acquisition of physiolo...
Metabolic hormones, nitric oxide signaling components, and inflammation markers crosstalk in coronary artery disease [0.03%]
代谢激素、一氧化氮信号分子和炎症标志物在冠状动脉疾病中的相互作用
Nadezhda G Gumanova,Natalya L Bogdanova,Anton R Kiselev
Nadezhda G Gumanova
Objectives: To assess the crosstalk between the serum levels of the metabolic hormones, NO-signaling components, and inflammation markers in patients with coronary artery disease (CAD) with 3-year follow-up. ...