Therapeutic and Preventive Role of Integrated Moderate-to-Vigorous Recreational Activity Programs in Type 2 Diabetes Care: A Systematic Review and Meta-Analysis [0.03%]
中等至高强度综合性休闲活动在2型糖尿病防治中的作用：系统综述和荟萃分析
Vandana Esht,Abhishek Sharma,Mohammed M Alshehri et al.
Vandana Esht et al.
Introduction: The global burden of type 2 diabetes mellitus (T2DM) is rising, with physical inactivity being a key modifiable risk factor. While structured exercise is known to improve glycemic control, the role of integr...
Selection of Endothelin Receptor Antagonists in the Treatment of Pulmonary Arterial Hypertension: A Comprehensive Narrative Review [0.03%]
肺动脉高压内皮素受体拮抗剂选用：综述
Naomi G Habib,Ankita Adhia,David Lopez et al.
Naomi G Habib et al.
One of the major mechanisms in the pathogenesis of pulmonary arterial hypertension (PAH) is mediated by elevated levels of endothelin (ET)-1, which activates both ETA and ETB receptors in the pulmonary vasculature. Endothelin receptor antag...
Evaluating the Cost-Effectiveness of Real-Time Continuous Glucose Monitoring Versus Self-Monitoring of Blood Glucose in the Treatment of Patients with Insulin-Treated Type 2 Diabetes in Australia [0.03%]
评估实时连续血糖监测相对于自我监测血糖在澳大利亚胰岛素治疗的2型糖尿病患者中的成本效益分析
Hamza Alshannaq,David Simmons,Jessica Y Matuoka et al.
Hamza Alshannaq et al.
Introduction: Type 2 diabetes (T2D) is a major public health concern in Australia, associated with substantial clinical, humanistic, and economic burden. The condition is linked to high rates of cardiovascular and microva...
Cost-Utility Analysis of Subcutaneous Methotrexate in the Treatment of Patients with Rheumatoid Arthritis in the UK [0.03%]
英国RA患者皮下注射甲氨蝶呤治疗的成本效用分析研究
Matthew Tucker,Johannes Pöhlmann,Kristin Grabe-Heyne et al.
Matthew Tucker et al.
Introduction: Oral methotrexate is the standard first-line treatment for rheumatoid arthritis (RA), but subcutaneous methotrexate may offer improved efficacy and tolerability and, as a second-line treatment, delay escalat...
Gil Yosipovitch,Brian S Kim,Sonja Ständer et al.
Gil Yosipovitch et al.
Atopic dermatitis (AD) is a chronic, relapsing, and heterogeneous skin disease characterized by eczematous morphology and intense pruritus, significantly impacting the quality of life of affected individuals. A primary cytokine implicated i...
Clinical Characteristics and Patient Burden of Cluster Headache in Brazil: A Real-World Study [0.03%]
巴西临床簇头痛的患病特征及疾病负担：一项真实世界研究
Taleen Karnieg,Maurice Vincent,James Martinez et al.
Taleen Karnieg et al.
Introduction: Cluster headache (CH) is a debilitating condition with health-related and economic burden to patients, including reduced quality of life (QoL) and suicidality. Brazilian data on comorbidities, symptoms, or i...
Comparative Efficacy and Safety of Tislelizumab in Second-Line Esophageal Squamous Cell Carcinoma: Systematic Literature Review and Simulated Treatment Comparisons [0.03%]
替雷利珠单抗二线治疗食管鳞癌的有效性和安全性：系统文献回顾和模拟治疗比较研究
Jaffer A Ajani,Kaijun Wang,Georgios F Nikolaidis et al.
Jaffer A Ajani et al.
Introduction: Esophageal squamous cell carcinoma (ESCC) accounts for approximately 90% of all esophageal cancer cases and is associated with poor prognosis. However, recent advancements have transformed the treatment land...
Optimizing the Use of Inhaled Corticosteroid/Long-Acting β2-Agonist Combinations in Patients with Moderate-to-Severe Asthma [0.03%]
哮喘中重度哮喘患者吸入皮质类固醇/长效β受体激动剂复合制剂使用的优化策略分析
Gabriel Garcia,Kittipong Maneechotesuwan,Prabhuram Krishnan et al.
Gabriel Garcia et al.
Current clinical recommendations for asthma management are based on a symptom-driven, stepwise approach; however, the effects of patient characteristics and patient preference should be considered as they can influence adherence and, in tur...
Economic Burden of Primary Biliary Cholangitis by Line of Therapy in the United States [0.03%]
美国按治疗线划分的原发性胆汁性胆管炎的经济负担
Sonal Kumar,Nisreen Shamseddine,Hongbo Yang et al.
Sonal Kumar et al.
Introduction: Lack of or delayed treatment of primary biliary cholangitis (PBC) is associated with worsening outcomes. This study assessed the real-world healthcare resource use (HRU) and costs of PBC in the USA to unders...
Six-Month Safety and Effectiveness of Teduglutide in Patients with Short Bowel Syndrome in Japan: Interim Analysis of Post-marketing Surveillance [0.03%]
teduglutide治疗短肠综合征患者6个月安全性和有效性的日本上市后监测 interim分析
Motoshi Wada,Shiro Nakamura,Ayako Hayashi et al.
Motoshi Wada et al.
Introduction: Patients with intestinal failure caused by short bowel syndrome (SBS) are dependent on parenteral support (PS) for nutrition. Teduglutide, an analogue of glucagon-like peptide 2, has been shown to decrease r...