AFP-producing gastric cancer and hepatocellular carcinoma with discrepancies in AFP-L3 expression [0.03%]
Ayana Kishibuchi,Azusa Sakamoto,Takaki Sakurai et al.
Ayana Kishibuchi et al.
Alpha-fetoprotein (AFP) is widely used as a tumor biomarker in the diagnosis and surveillance of hepatocellular carcinoma (HCC). AFP is a glycoprotein bearing N-linked glycans, and can be classified into three glycoforms: AFP-L1, AFP-L2, an...
Simultaneous gastric and colonic metastasis of invasive lobular carcinoma of the breast [0.03%]
乳腺浸润性小叶癌同时发生胃和结肠转移
Seri Okawa,Hideharu Ogiyama,Takahiro Amano et al.
Seri Okawa et al.
Breast cancer commonly metastasizes to the lungs, bones, liver, and brain; however, gastrointestinal involvement is uncommon. Simultaneous metastases to both the stomach and colon are extremely rare. We report the case of a 53-year-old woma...
Perihepatic dedifferentiated liposarcoma mimicking IgG4-related disease [0.03%]
肝周未分化脂肪肉瘤伴IgG4相关性疾病表现的一例
Soushi Shibusawa,Yuki Yamashita,Tomoyuki Tanaka et al.
Soushi Shibusawa et al.
Background: Dedifferentiated liposarcoma (DDLPS) may originate in perihepatic adipose tissue, but can radiologically present as a hepatic mass. Moreover, dense Immunoglobulin G4 (IgG4)-positive plasma cell infiltration ma...
Rapid regression of advanced hepatic fibrosis in a patient with metabolic dysfunction-associated steatotic liver disease and severe obesity: a case report highlighting lifestyle-induced NETosis activation through serum proteomic analysis [0.03%]
代谢功能障碍相关肝脂肪变性疾病合并重度肥胖患者的 advanced 纤维化快速消退一例报告：通过血清蛋白质组学分析突出生活方式诱导的NETosis激活
Toru Nakamura,Shigemune Bekki,Dan Nakano et al.
Toru Nakamura et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a progressive condition linked to obesity and insulin resistance, potentially leading to cirrhosis. While lifestyle intervention is a primary treatment, the molecular mecha...
Covert hepatic encephalopathy in cirrhosis: implications for early diagnosis and appropriate management [0.03%]
肝硬化的隐性肝性脑病：早期诊断和合理治疗的启示
Chisato Saeki,Takahiko Toyonaga,Yuichi Torisu et al.
Chisato Saeki et al.
Covert hepatic encephalopathy (CHE) is a frequent and clinically relevant complication of liver cirrhosis, affecting approximately 30-70% of patients. Despite the absence of overt neurological symptoms, CHE is associated with impaired quali...
Takotsubo syndrome following delayed bleeding after gastric endoscopic submucosal dissection: a case report [0.03%]
胃内镜黏膜下剥离术后迟发性出血后发生应激性心肌病(Tako-Tsubo综合征)的病例报告
Yoshika Saito,Masaki Nakashima,Hiroaki Saito et al.
Yoshika Saito et al.
Endoscopic submucosal dissection (ESD) is a minimally invasive treatment for early gastric cancer that enables the en bloc resection of large lesions. However, it is associated with a significant risk of delayed bleeding, particularly in pa...
Durvalumab and tremelimumab combination therapy achieved remarkable response in primary hepatic undifferentiated carcinoma with high PD-L1 expression [0.03%]
对于高PD-L1表达原发性肝未分化癌患者采用度伐单抗和特瑞普利单抗联合治疗取得了显著疗效
Michihiko Kawahara,Hatsue Fujino,Yasutoshi Fujii et al.
Michihiko Kawahara et al.
Primary hepatic undifferentiated carcinoma is an extremely rare and aggressive malignancy with no established systemic therapy, and the efficacy of immune checkpoint inhibitors (ICIs) remains unknown. We report a 67-year-old man with compen...
Mehmet Akif Agir
Mehmet Akif Agir
Lymphoepithelial carcinoma of the esophagus with primary squamous cell carcinoma of the hypopharynx: complete response was achieved by chemoradiation therapy [0.03%]
合并下咽鳞癌的食管淋巴上皮癌一例及化学放射治疗有效报告
Hirotaka Kashima,Akihisa Fukuda,Takafumi Kurokami et al.
Hirotaka Kashima et al.
A 52-year-old male presented with a 3-month history of dysphagia. Laryngological examination showed a left-sided hypopharyngeal tumor, and biopsy of biopsy the tumor revealed moderately differentiated squamous cell carcinoma (SCC). Computed...
A case of immune-mediated adverse events enterocolitis and duodenitis with gastrointestinal bleeding successfully treated with ustekinumab [0.03%]
一例乌司奴单抗成功治疗的免疫介导性不良反应：结肠炎和十二指肠炎伴胃肠出血
Ryo Morikawa,Yuka Hachisu,Toshimitsu Fujii et al.
Ryo Morikawa et al.
Gastrointestinal immune-mediated adverse events (imAEs) complicated by bleeding may result in a severe clinical course. We report the case of a 64-year-old man with immune-mediated colitis who relapsed after initial treatment with prednisol...