Engineered living materials: emerging frontiers in therapeutic innovation and management of skin disorders [0.03%]
工程化活体材料：皮肤疾病治疗和管理的新兴前沿领域与创新疗法
Rideb Chakraborty,Naureen Afrose,Sourav Ghosh et al.
Rideb Chakraborty et al.
Engineered living material (ELM) is a new paradigm in biomaterials science that merges synthetic biology with materials engineering to create dynamic, responsive systems with living functionalities. This review explores to what extent ELMs ...
Assessing the bioactive potential of Lysimachia atropurpurea extracts using HPLC-MS/MS, in vitro and in silico analysis [0.03%]
基于HPLC-MS/MS、体外和分子对接评估Lysimachia atropurpurea的生物活性潜力
Gunes Ak,Nilofar Nilofar,Enver Saka et al.
Gunes Ak et al.
The genus Lysimachia is of great interest to the scientific community, especially in terms of its potential anticancer effects. In this study, the aerial parts and roots of Lysimachia atropurpurea L. were collected and extracted by macerati...
Syzydyerin A, a new unusual C-methylated chalcone isolated from the leaves of Syzygium dyerianum (King) Chantar. & J.Parn [0.03%]
来自山黄葵树叶的新异丙基取代查尔酮类化合物Syzydyerin A
Faezatul Alwani Mohd Rahim,Wan Mohd Nuzul Hakimi Wan Salleh,Nurunajah Ab Ghani et al.
Faezatul Alwani Mohd Rahim et al.
A new unusual C-methylated chalcone was successfully isolated from the leaves of Syzygium dyerianum (King) Chantaran. & J.Parn, identified as syzydyerin A (1), together with β-sitosterol, friedelin and lupeol. The characterisation and stru...
Natural deep eutectic solvents: composition, preparation, and applications in food, pharmaceutical, and biomedical sciences [0.03%]
天然深共熔溶剂：组成、制备及其在食品、制药和生物医学科学中的应用
Sangeeta Yadav,Alka Sharma,Akash Kumar et al.
Sangeeta Yadav et al.
Natural deep eutectic solvents (NADES) have emerged as a green, sustainable alternative to conventional organic solvents due to their biocompatibility and non-toxicity. This review highlights the composition and structural diversity of NADE...
GC-MS analysis, anti-inflammatory, anti-coagulant, and antioxidant activities of Silybum marianum extracts [0.03%]
乳香玛丽安提取物的气相色谱-质谱分析及抗炎、抗凝和抗氧化活性研究
Ahlem Karbab,Nuha Sweidan,Ashok K Shakya et al.
Ahlem Karbab et al.
Synthetic medicinal products are expensive and may have serious side effects. In addition, other antimicrobial agents have become increasingly required due to antibiotic resistance. To overcome these problems, people have used medicinal pla...
ST8SIA4-mediated N-glycosylation of hENT1 suppresses gemcitabine resistance in pancreatic cancer [0.03%]
ST8SIA4介导的hENT1岩藻糖基化抑制胰腺癌的吉西他滨耐药性
Chang Xin,Yifeng Wu,Haiming Li et al.
Chang Xin et al.
Gemcitabine (GEM) serves as a first-line chemotherapeutic agent for pancreatic cancer (PC), but its clinical efficacy is significantly limited by the emergence of drug resistance, necessitating in-depth exploration of the underlying molecul...
Phytochemical characterization and multi-biological potentials of Inula viscosa: new in vitro evidence [0.03%]
伊娃植物化学特征及多生物潜力的体内新证据
Yasemin Celik Altunoglu,Mustafa Ocal,Mehmet Cengiz Baloglu et al.
Yasemin Celik Altunoglu et al.
Inula viscosa is a common medicinal plant and is mostly spread in Mediterranean countries. The current study analyses I. viscosa extracts for antimicrobial capacity, phenolic content, antioxidant, enzyme inhibition, and molecular modeling. ...
Flavonoid derivatives from red propolis: In silico predictions of their interactions with Staphylococcus aureus sortase A and studies on their antibiofilm potential [0.03%]
来源于红巴西 Propolis 的黄酮类衍生物：针对金黄色葡萄球菌连接酶A的计算机虚拟筛选及其抗生物膜活性研究
Dipto Kumer Sarker,Emma Ratcliffe,Fraser Burnett et al.
Dipto Kumer Sarker et al.
Sortase A (SrtA) is an enzyme essential for biofilm formation in Gram-positive bacteria including Staphylococcus aureus. In silico investigations were conducted to investigate the interactions of flavonoid derivatives from red propolis with...
Nucleic acid nanoscale constructs for transformative frontier in theranostics [0.03%]
用于治疗诊断前沿的核酸纳米结构
Venkatakrishnan Kiran,Koyeli Girigoswami,Agnishwar Girigoswami
Venkatakrishnan Kiran
Using the intrinsic qualities of nucleic acids-biocompatibility, programmability, and precise self-assembly - DNA and RNA nanostructures represent a revolutionary new frontier in theranostics, bridging the gap between diagnostics and treatm...
Equisarmine, a new steroidal glycoalkaloid, from sterile stems of Equisetum arvense [0.03%]
源自无性植物节茎草Equisetum arvense的新型甾醇类糖生物碱Equisarmine
Atsumi Shimada,Hiroshi Ueno,Kohei Kawabata et al.
Atsumi Shimada et al.
Glutaminase is an important target that is often over expressed in neurodegenerative and lifestyle related diseases but few effective inhibitors of this enzyme have yet reached clinical trials. To select plants with high glutaminase inhibit...