Mantle cell lymphoma transformation to CD19-negative classic Hodgkin lymphoma as a novel mechanism of escape from CD19 chimeric antigen receptor T cell therapy [0.03%]
套细胞淋巴瘤转化为CD19阴性经典霍奇金淋巴瘤作为逃避CD19嵌合抗原受体T细胞治疗的新机制
Yu Yu,Michael Bayerl,Shin Mineishi et al.
Yu Yu et al.
Mantle cell lymphoma (MCL) is a mature B cell neoplasm characterized by the CCND1::IgH t(11;14) translocation. The process of MCL clonal evolution remains poorly understood. In this report, we describe a rare case of a patient with blastoid...
Eilena Braye,Laurence de Leval
Eilena Braye
ALK-positive anaplastic large cell lymphoma (ALCL) may show sinusoidal involvement, but exclusive intrasinusoidal infiltration of lymph nodes is exceptionally rare. We describe a 39-year-old woman with isolated stage I inguinal lymphadenopa...
From famine to feast: a seesawing platelet count in severe iron deficiency anemia [0.03%]
从缺铁性贫血导致的血小板减少到血小板增多——一波三折的经历
Allison Weisnicht,Eduard Matkovic
Allison Weisnicht
A 22-month-old previously healthy girl presented with profound microcytic anemia and severe thrombocytopenia due to iron deficiency. Following transfusions and iron supplementation, her platelet count rose dramatically, peaking at 3.5 milli...
Rare variant hemoglobin Köln in Southern India-an underdiagnosed entity? [0.03%]
印度南部罕见的变体血红蛋白柯隆-一个被低估的诊断对象吗？
Swathi Kulkarni,Deepalakshmi D Putchen,Pradeep Kumar Venkatachala et al.
Swathi Kulkarni et al.
We report a 15-year-old boy from Karnataka, India, initially misdiagnosed as HbE/β-thalassemia. On follow-up, Capillary electrophoresis (CE) showed a 3.3% peak in Zone 4, with the WBC Differential Fluorescence (WDF) scattergram on the Sysm...
A novel IKZF1::FAM3C fusion associated with inversion of chromosome 7, inv(7)(p13q32), in relapsed acute myeloid leukemia [0.03%]
染色体7臂内倒位（inv（7）（p13q32））与复发性急性髓系白血病相关的IKZF1::FAM3C融合新亚型
Haiming Tang,Mingfei Yan,Yanming Zhang et al.
Haiming Tang et al.
Background: Acute myeloid leukemia (AML) is characterized by myeloid blasts in the bone marrow and peripheral blood, and it is a highly heterogenous disease genetically. Although our understanding of AML genetics has adva...
A novel splicing variant of CNTRL::FGFR1 in myeloid/lymphoid neoplasm with eosinophilia and rearrangement of FGFR1 [0.03%]
关于含FGFR1重排的嗜酸细胞性髓系/淋巴组织肿瘤的一种新的拼接变异CNTRL:FGFR1
Xianqi Feng,Xueting Bai,Hong Zhang et al.
Xianqi Feng et al.
Background Myeloid/lymphoid neoplasm with eosinophilia and rearrangement of FGFR1(MLN-FGFR1), also referred to as 8p11 myeloproliferative syndrome (EMS), arises from aberrant FGFR1 gene rearrangement in bone marrow hematopoietic stem cells,...
IgG4 plasma cells in hematopathology: beyond IgG4-related disease [0.03%]
IgG4浆细胞在血液病理学中的作用：超越IgG4相关疾病的影响
Vaclav Stejskal,Tereza Sokolova,Jakub Sagat et al.
Vaclav Stejskal et al.
IgG4 plasma cells are well-known in the context of IgG4-related disease (IgG4-RD). Meanwhile, their role in other disorders remains enigmatic. In hematopathology practice, the presence of these cells can be non-specific in reactive lymphade...
Primary hyaline vascular Castleman disease in the kidney: a report and brief literature review [0.03%]
主透明血管细胞型卡斯特尔曼病肾受累一例并文献复习
Ibrahim Elsharawi,Sorin Selegean
Ibrahim Elsharawi
Castleman disease is an uncommon lymphoproliferative disorder that usually involves lymph nodes but can rarely present in extranodal sites. We describe an unusual case of Castleman disease exclusively involving the kidney. The authors also ...
Age, gender, and ethnicity are associated with higher all-cause mortality in hospitalized patients with heparin-induced thrombocytopenia: a nationwide analysis [0.03%]
年龄、性别和种族与肝素诱导的血小板减少症住院患者的全因死亡率增加有关：全国范围内的分析
Michelle Devlin,Mohammad Reza Movahed,Mehrtash Hashemzadeh et al.
Michelle Devlin et al.
Introduction: Heparin-induced thrombocytopenia (HIT) is a life-threatening immunologic reaction to heparin exposure that is associated with substantial morbidity and mortality. Limited research is available on host-depend...
Validation and interpretation of the Triple A model in Turkish myeloproliferative neoplasm patients with a focus on overall and thrombosis free survival [0.03%]
土耳其血小板增多症患者中Triple A模型的验证与解读——重点关注总生存率和无血栓生存率
Mehmet Baysal,Sevil Sadri,Özgür Ömer Gül et al.
Mehmet Baysal et al.
Background: The Triple A model has recently been developed and validated in essential thrombocythemia (ET) and polycythemia vera (PV). However, external validation in diverse populations remains unclear. ...
Multicenter Study
Journal of hematopathology. 2025 Nov 5;18(1):50. DOI:10.1007/s12308-025-00668-0 2025