Elodie Cretel,Anne Pierres,Anne-Marie Benoliel et al.
Elodie Cretel et al.
It is now well demonstrated that cell adhesion to a foreign surface strongly influences prominent functions such as survival, proliferation, differentiation, migration or mediator release. Thus, a current challenge of major practical and th...
Rho Kinase Regulation of Fibroblast Migratory Mechanics in Fibrillar Collagen Matrices [0.03%]
rho蛋白激酶调节成纤维细胞在胶原支架中的迁移性质
Chengxin Zhou,W Matthew Petroll
Chengxin Zhou
Migration of activated corneal fibroblasts plays an important role in matrix patterning during embryonic development and wound repopulation following injury or refractive surgery. In this study, we investigate the role of Rho kinase in regu...
Effects of Axial Stretch on Cell Proliferation and Intimal Thickness in Arteries in Organ Culture [0.03%]
轴向牵张对器官培养动静脉内膜厚度及细胞增殖的影响
Yong-Ung Lee,Danika Hayman,Eugene A Sprague et al.
Yong-Ung Lee et al.
Intimal hyperplasia (IH) remains the major cause of intermediate and long-term failure of vascular grafts and endovascular interventions. Arteries are subjected to a significant longitudinal stress in addition to the shear stress and tensil...
Substrate Stiffness and Cell Area Predict Cellular Traction Stresses in Single Cells and Cells in Contact [0.03%]
基质刚度与细胞面积预测单个细胞及相互接触的细胞的细胞牵引力应力
Joseph P Califano,Cynthia A Reinhart-King
Joseph P Califano
Cells generate traction stresses against their substrate during adhesion and migration, and traction stresses are used in part by the cell to sense the substrate. While it is clear that traction stresses, substrate stiffness, and cell area ...
Quantification of Lacunar-Canalicular Interstitial Fluid Flow Through Computational Modeling of Fluorescence Recovery After Photobleaching [0.03%]
基于光漂白后荧光恢复的计算模型定量分析穿孔-小管间质液流量
Ronald Y Kwon,John A Frangos
Ronald Y Kwon
Skeletal adaptation to mechanical loading has been widely hypothesized to involve the stimulation of osteocytes by interstitial fluid flow (IFF). However, direct investigation of this hypothesis has been difficult due in large part to the i...
Surface Plasmon Resonance Monitoring of Cell Monolayer Integrity: Implication of Signaling Pathways Involved in Actin-Driven Morphological Remodeling [0.03%]
基于表面等离子体共振的单层细胞完整性的检测：与肌动蛋白驱动的形态重塑相关的信号途径的含义
Charles M Cuerrier,Vincent Chabot,Sylvain Vigneux et al.
Charles M Cuerrier et al.
Morphological changes occurring in individual cells largely influence the physiological functions of various cell layers. The control of barrier function of epithelia and endothelia is a prime example of processes highly dependent on cellul...
Shapes of Red Blood Cells: Comparison of 3D Confocal Images with the Bilayer-Couple Model [0.03%]
红细胞的形状：三维共聚焦图像与双层耦合模型的比较
Khaled Khairy,Jijinn Foo,Jonathon Howard
Khaled Khairy
Cells and organelles are shaped by the chemical and physical forces that bend cell membranes. The human red blood cell (RBC) is a model system for studying how such forces determine cell morphology. It is thought that RBCs, which are typica...
Mechanical Forces in Endothelial Cells during Firm Adhesion and Early Transmigration of Human Monocytes [0.03%]
人单核细胞在牢固黏附和早期迁移过程中内皮细胞的机械力作用
Zhijun Liu,Nathan J Sniadecki,Christopher S Chen
Zhijun Liu
Transmigration of leukocytes across the endothelial barrier is a tightly controlled process involving multiple steps, including rolling adhesion, firm adhesion, and then penetration of leukocytes through the endothelial monolayer. While the...
Bo Huo,Xin L Lu,Clark T Hung et al.
Bo Huo et al.
In our previous work, bone cell networks with controlled spacing and functional intercellular gap junctions had been successfully established by using microcontact printing and self assembled monolayers technologies [Guo, X. E., E. Takai, X...
A Trabecular Bone Explant Model of Osteocyte-Osteoblast Co-Culture for Bone Mechanobiology [0.03%]
一种用于骨骼力学生物学的骨小梁骨组织外植体共培养模型： osteocyte-osteoblast co-culture
Meilin Ete Chan,Xin L Lu,Bo Huo et al.
Meilin Ete Chan et al.
The osteocyte network is recognized as the major mechanical sensor in the bone remodeling process, and osteocyte-osteoblast communication acts as an important mediator in the coordination of bone formation and turnover. In this study, we de...