Mechanical Trapping of the Cell Nucleus Into Microgroove Concavity But Not On Convexity Induces Cell Tissue Growth and Vascular Smooth Muscle Differentiation [0.03%]
细胞核被机械地限制在微凹槽中而不是凸起中可诱导组织生长和血管平滑肌分化
Kazuaki Nagayama,Naoki Wataya
Kazuaki Nagayama
Introduction: Vascular smooth muscle cells (VSMCs) in the normal aortic wall regulate vascular contraction and dilation. VSMCs change their phenotype from contractile to synthetic and actively remodel the aortic wall unde...
Correction: Assessing the Effects of Dasatinib on Mesenchymal Stem/Stromal Cells [0.03%]
关于达沙替尼对间充质干细胞/基质细胞的影响的更正论文：评估达沙替尼对间充质干细胞/基质细胞的影响
David P Heinrichs,Vitali V Maldonado,I Kade K Ardana et al.
David P Heinrichs et al.
[This corrects the article DOI: 10.1007/s12195-024-00830-1.]. © The Author(s) 2024.
Published Erratum
Cellular and molecular bioengineering. 2024 Nov 22;17(6):619. DOI:10.1007/s12195-024-00833-y 2024
A Multicellular Mechanochemical Model to Investigate Tumor Microenvironment Remodeling and Pre-Metastatic Niche Formation [0.03%]
一种多细胞力化学模型用于探究肿瘤微环境重塑和前转移生态位形成
Shreyas U Hirway,Kylie G Nairon,Aleksander Skardal et al.
Shreyas U Hirway et al.
Introduction: Colorectal cancer (CRC) is a major cause of cancer related deaths in the United States, with CRC metastasis to the liver being a common occurrence. The development of an optimal metastatic environment is ess...
Michael R King
Michael R King
David P Heinrichs,Vitali V Maldonado,I Kade K Ardana et al.
David P Heinrichs et al.
Introduction: Progressive aging, or senescence, of mesenchymal stem/stromal cells (MSCs) is a major obstacle faced when trying to culture potent stem cells for use in therapy. Senescent cells are irreversibly nondividing ...
Novel 3-D Macrophage Spheroid Model Reveals Reciprocal Regulation of Immunomechanical Stress and Mechano-Immunological Response [0.03%]
新颖的三维巨噬细胞球体模型揭示了免疫机械应力与力学免疫反应之间的互惠调节关系
Alice Burchett,Saeed Siri,Jun Li et al.
Alice Burchett et al.
Purpose: In many diseases, an overabundance of macrophages contributes to adverse outcomes. While numerous studies have compared macrophage phenotype after mechanical stimulation or with varying local stiffness, it is unc...
Empowering High-Throughput High-Content Analysis of Microphysiological Models: Open-Source Software for Automated Image Analysis of Microvessel Formation and Cell Invasion [0.03%]
高通量、高内涵分析微生理模型的实现：开放获取的软件助力血管生成和细胞侵袭的自动化图像分析
Noah Wiggin,Carson Cook,Mitchell Black et al.
Noah Wiggin et al.
Purpose: The primary aim of this study was to develop an open-source Python-based software for the automated analysis of dynamic cell behaviors in microphysiological models using non-confocal microscopy. This research see...
Probing the Effects of Chirality on Self-Assembling Peptides: Hydrogel Formation, Degradation, Antigen Release, and Adjuvancy [0.03%]
手性对自组装肽的影响探究：水凝胶形成、降解、抗原释放和佐剂效应
Anushka Agrawal,Erin M Euliano,Brett H Pogostin et al.
Anushka Agrawal et al.
Introduction: Multidomain peptides (MDPs) are amino acid sequences that self-assemble to form supramolecular hydrogels under physiological conditions that have shown promise for a number of biomedical applications. K2(SL)...
Chloe P Whitworth,Wen Y Aw,Elizabeth L Doherty et al.
Chloe P Whitworth et al.
Purpose: P300 is a lysine acetyltransferase that plays a significant role in regulating transcription and the nuclear acetylome. While P300 has been shown to be required for the transcription of certain early flow respons...