Feasibility of targeted alpha therapy for Alzheimer's disease using 211At-labeled agent targeting amyloid-β aggregates [0.03%]
使用211At标记的靶向淀粉样蛋白-β聚集物药物治疗阿尔茨海默病的可能性研究
Rikuto Kashiyama,Hiroyuki Watanabe,Takahiro Akasaka et al.
Rikuto Kashiyama et al.
Objective: Amyloid-β (Aβ) aggregates have been recognized as therapeutic targets for Alzheimer's disease (AD). Targeted alpha therapy (TAT) using α-particles has the potential to be applied as a novel treatment approac...
Are [18F]FDG PET/CT imaging and cell blood count-derived biomarkers robust non-invasive surrogates for tumor-infiltrating lymphocytes in early-stage breast cancer? [0.03%]
[18F]FDG PET/CT影像和基于细胞血计数的生物标志物能作为早期乳腺癌浸润性淋巴细胞的无创替代标志物吗？
Romain-David Seban,Louis Rebaud,Lounes Djerroudi et al.
Romain-David Seban et al.
Objective: Tumor-infiltrating lymphocytes (TILs) are key immune biomarkers associated with prognosis and treatment response in early-stage breast cancer (BC), particularly in the triple-negative subtype. This study aimed ...
Diagnostic value of FDG PET/CT in determining the etiology of pericardial effusion [0.03%]
FDG PET/CT在确定心包积液病因中的诊断价值
Jinchuan Chen,Qian Wang,Yuan Li et al.
Jinchuan Chen et al.
Objective: To analyze the imaging characteristics of FDG PET/CT in pericardial effusions from various etiologies and evaluate its diagnostic utility for differentiating these etiologies. ...
Recent advances in theranostics and oncology PET: emerging radionuclides and targets [0.03%]
治疗诊断和肿瘤PET的最新进展：新兴放射性示踪剂和靶点
Tadashi Watabe,Kenji Hirata,Mami Iima et al.
Tadashi Watabe et al.
Theranostics, a novel integrated approach that combines cancer diagnosis and therapy by switching the radionuclide, has attracted growing attention. Various oncology PET probes other than FDG have been developed for the highly sensitive and...
Prognostic value of FDG-PET/CT findings in mucosal melanoma of the head and neck treated with carbon ion radiotherapy [0.03%]
正电子发射断层扫描/计算机断层扫描对碳离子放疗头颈部黏膜黑色素瘤的预后价值研究
Ayako Hino,Nobutaka Mizoguchi,Hiroaki Koge et al.
Ayako Hino et al.
Objective: To investigate the prognostic value of 18F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT) in patients with mucosal melanoma of the head and neck (MMHN) treated with carbon ion ...
Clinical Practice Guidelines for 18F-Fluciclovine 2024 in the Japanese Society of Nuclear Medicine [0.03%]
日本核医学会18F-氟氯霉素2024临床实践指南
Kimiteru Ito,Seishi Jinnouchi,Kaoru Kikukawa et al.
Kimiteru Ito et al.
18F-Fluciclovine was the first 18F-labeled amino acid PET tracer to be approved for clinical use in Japan, receiving regulatory approval in March 2021 and being listed for reimbursement in June 2024. In response to this development, the Jap...
Distribution patterns of brown adipose tissue on FDG-PET/CT has age characteristics [0.03%]
18F-FDG PET/CT影像中棕色脂肪组织分布规律的年龄特点分析
Yasuchiyo Toyama,Tomoya Kotani,Nagara Tamaki et al.
Yasuchiyo Toyama et al.
Purpose: Brown adipose tissue (BAT) contributes to thermoregulation and energy expenditure. Although BAT is abundant in early childhood and declines with age, its distribution across age groups remains unclear. This study...
Innovations in clinical PET image reconstruction: advances in Bayesian penalized likelihood algorithm and deep learning [0.03%]
临床PET图像重建创新：贝叶斯似然算法及深度学习进展
Kenta Miwa,Tensho Yamao,Fumio Hashimoto et al.
Kenta Miwa et al.
Recent advances in PET image reconstruction have focused on achieving high image quality and quantitative accuracy. Bayesian penalized likelihood (BPL) algorithms, such as Q.Clear and HYPER Iterative that have been integrated into commercia...
Comparison of diagnostic performance between manual diagnosis following PROMISE V2 and aPROMISE utilizing Ga/F-PSMA PET/CT [0.03%]
基于Ga/F-PSMA PET/CT手动读片与aPROMISE的诊断效能比较研究
Yuki Enei,Takafumi Yanagisawa,Atsuya Okada et al.
Yuki Enei et al.
Backgrounds: Automated PROMISE (aPROMISE), which is an artificial intelligence-supported software for prostate-specific membrane antigen (PSMA) PET/CT based on PROMISE V2, has demonstrated diagnostic utility with better c...
Kinetic and quantitative analysis of [18F]SMBT-1 PET imaging for monoamine oxidase B [0.03%]
基于[18F]SMBT-1的多巴胺转运体PET显像的定量及动力学分析
Kotaro Hiraoka,Berihu Mesfin,Yingying Wu et al.
Kotaro Hiraoka et al.
Background and objective: In neuroinflammation, activated astrocytes, called reactive astrocytes, highly express monoamine oxidase B (MAO-B). [18F]SMBT-1 is a novel PET tracer developed for imaging neuroinflammation, with...