Auditory conditioned fear elicits anxiety-like behavior and differential neuronal remodeling in the prelimbic and infralimbic cortex of rats [0.03%]
听觉条件化恐惧诱发大鼠前扣带回和内侧前额叶皮层的焦虑样行为及不同神经重塑反应
Iris Dalia Vázquez-Vargas,Gonzalo Flores,Julio César Morales-Medina et al.
Iris Dalia Vázquez-Vargas et al.
Fear and anxiety are adaptive responses that promote survival. Defensive immobility, including tonic and dorsal forms, is a multisensory behavior. However, the relationship between learned fear and immobility, as well as underlying cortical...
Zachary Cofran,Shawn Hurst,John Hawks
Zachary Cofran
Endocasts are casts of the internal surface of skull bones created by the brain and surrounding tissues. These fossil phantoms provide the most direct evidence of the brains of extinct organisms, and are one of the many puzzle pieces that h...
Ultrastructural response of the retinal cells and neurovascular unit to neuroinflammation induced by lipopolysaccharide [0.03%]
脂多糖诱导的神经炎症下视网膜细胞及神经血管单位的超微结构反应
Bilin Rao,Xiaotian Wu,Xiaoqing Liu et al.
Bilin Rao et al.
Inflammation within the central nervous system (CNS) plays a pivotal role in neuronal survival and degeneration. Lipopolysaccharide (LPS) is a widely used agent for inducing systemic and localized inflammation in mammals, providing a model ...
The effect of canagliflozin on hippocampal dendrite morphology in a model of Alzheimer's disease induced by intracerebroventricular injection of streptozotocin [0.03%]
卡格列净对脑室内注射链脲佐菌素诱导的阿尔茨海默病模型小鼠海马树突形态的影响
Sevdenur Yazi,Berna Ozen,Bahar Buldu et al.
Sevdenur Yazi et al.
Alzheimer's disease (AD) and diabetes mellitus (DM) share common pathophysiological features. However, the effects of antidiabetic drugs on neurodegeneration are not completely known. Canagliflozin, a novel option for DM treatment, is a dua...
Early-stage olfactory bulbectomy induces hyperlocomotion with increased astrocyte and microglial density in the prefrontal cortex of male rats [0.03%]
早期嗅球切除术可诱导雄性大鼠前额叶皮质胶质细胞和小胶质细胞密度增加及运动过度
Mario Alberto Bautista-Carro,Diana Moroni-González,Julia Flores-Tochihuitl et al.
Mario Alberto Bautista-Carro et al.
Major depressive disorder (MDD) severely affects people's productivity and quality of life. Olfactory bulbectomy (OBX) yields reproducible behavioral changes resembling agitated depression. Since most studies examine models after the depres...
Structure-function dynamics in healthy cognitive aging: a graph signal processing approach [0.03%]
图信号处理方法在健康认知老化中的结构功能动态研究
Clément Guichet,Sophie Achard,Martial Mermillod et al.
Clément Guichet et al.
Network neuroscience has significantly advanced our understanding of how structural and functional connectivity evolve during healthy neurocognitive aging. Yet, integrative studies linking structural and functional brain organization with c...
Task-dependent neural dynamics in hippocampal CA1 during auditory and visual perceptual decision-making in rats [0.03%]
大鼠在听觉和视觉知觉决策过程中的海马CA1区神经动力学特征
ShuHua Mu,XiaoSheng Yang,Xian Jiang et al.
ShuHua Mu et al.
Perceptual decision-making involves the integration and evaluation of sensory evidence to guide behavior, yet the extent to which the hippocampus contributes to decision processes across sensory contexts remains unclear. This study combined...
Stephanie J Forkel,Lilit Dulyan,Kurt Schilling et al.
Stephanie J Forkel et al.
Neurovariability refers to the naturally occurring differences in brain structure and functional organisation across individuals. Rather than being noise, this variability reflects an adaptive feature of human neurobiology, supporting diver...
Disrupted integration-segregation balance in the intact hemisphere in chronic spatial neglect [0.03%]
慢性空间忽略患者完整半球中整合-分离平衡的破坏
Yusaku Takamura,Marine Lunven,Yvonne Serhan et al.
Yusaku Takamura et al.
Spatial neglect is a common and disabling consequence of right hemisphere stroke, characterized by a failure to attend to the contralesional left space, and frequently persists into the chronic stage. There is robust evidence on the role of...
Characterizing functional connectivity gradients for the hippocampus-amygdala complex in healthy and psychiatric cohorts [0.03%]
健康人群和精神病受试者海马杏仁核复合体的功能连接梯度的特征研究
Xiang-Shen Liu,Janna N Vrijsen,Linlin Yan et al.
Xiang-Shen Liu et al.
The hippocampus and amygdala play essential roles in human cognition and emotion, through their extensive connectivity with other brain regions and close interaction between them. Uncovering the functional organization of the hippocampus-am...