Anaisa V Ferreira,Jorge Domínguez-Andrés,Laura M Merlo Pich et al.
Anaisa V Ferreira et al.
The innate immune system exhibits features of memory, termed trained immunity, which promote faster and more robust responsiveness to heterologous challenges. Innate immune memory is sustained through epigenetic modifications, affecting gen...
Harnessing the tumor microenvironment to boost adoptive T cell therapy with engineered lymphocytes for solid tumors [0.03%]
利用工程改造的淋巴细胞对固体肿瘤进行过继T细胞治疗并调动肿瘤微环境的作用
Martina Spiga,Elisa Martini,Maria Chiara Maffia et al.
Martina Spiga et al.
Adoptive cell therapy (ACT) using Chimeric Antigen Receptor (CAR) and T Cell Receptor (TCR) engineered T cells represents an innovative therapeutic approach for the treatment of hematological malignancies, yet its application for solid tumo...
The role of galectins in the regulation of autophagy and inflammasome in host immunity [0.03%]
半乳糖凝集素在宿主免疫自噬和炎性小体调节中的作用研究进展
Tzu-Han Lo,I-Chun Weng,Hung-Lin Chen et al.
Tzu-Han Lo et al.
Galectins, a family of glycan-binding proteins have been shown to bind a wide range of glycans. In the cytoplasm, these glycans can be endogenous (or "self"), originating from damaged endocytic vesicles, or exogenous (or "non-self"), found ...
Riding the storm: managing cytokine-related toxicities in CAR-T cell therapy [0.03%]
乘风破浪：CAR-T细胞治疗相关细胞因子释放综合征的管理
Andrew D Hughes,David T Teachey,Caroline Diorio
Andrew D Hughes
The advent of chimeric antigen receptor T cells (CAR-T) has been a paradigm shift in cancer immunotherapeutics, with remarkable outcomes reported for a growing catalog of malignancies. While CAR-T are highly effective in multiple diseases, ...
The role of microglia in early neurodevelopment and the effects of maternal immune activation [0.03%]
小胶质细胞在早期神经发育中的作用以及母体免疫激活的影响
L J M Mastenbroek,S M Kooistra,B J L Eggen et al.
L J M Mastenbroek et al.
Activation of the maternal immune system during gestation has been associated with an increased risk for neurodevelopmental disorders in the offspring, particularly schizophrenia and autism spectrum disorder. Microglia, the tissue-resident ...
Ralf Jacob,Lena-Sophie Gorek
Ralf Jacob
In the galectin family, a group of lectins is united by their evolutionarily conserved carbohydrate recognition domains. These polypeptides play a role in various cellular processes and are implicated in disease mechanisms such as cancer, f...
Victor L J L Thijssen
Victor L J L Thijssen
Sustained tumor angiogenesis, i.e., the induction and maintenance of blood vessel growth by tumor cells, is one of the hallmarks of cancer. The vascularization of malignant tissues not only facilitates tumor growth and metastasis, but also ...
Seungil Kim,Sang-Uk Seo,Mi-Na Kweon
Seungil Kim
The gut microbiota, housing trillions of microorganisms within the gastrointestinal tract, has emerged as a critical regulator of host health and homeostasis. Through complex metabolic interactions, these microorganisms produce a diverse ra...
Publisher Correction: Epithelial recognition and elimination against aberrant cells [0.03%]
出版更正：上皮细胞识别和清除异常细胞
Shiyu Ayukawa,Nagisa Kamoshita,Takeshi Maruyama
Shiyu Ayukawa
Published Erratum
Seminars in immunopathology. 2024 Jan;45(4-6):551-554. DOI:10.1007/s00281-024-01009-6 2024
Correction: Glycoprotein 2 as a gut gate keeper for mucosal equilibrium between inflammation and immunity [0.03%]
纠正：糖蛋白2作为肠道门卫，调节黏膜部位的炎症和免疫平衡
Zhongwei Zhang,Izumi Tanaka,Rika Nakahashi-Ouchida et al.
Zhongwei Zhang et al.
Published Erratum
Seminars in immunopathology. 2024 Jan;45(4-6):549-550. DOI:10.1007/s00281-024-01002-z 2024