Role of the gut microbiome in psychological symptoms associated with inflammatory bowel diseases [0.03%]
肠道微生物组在炎症性肠病相关心理症状中的作用
Konstantina Atanasova,Laura-Louise Knödler,Wolfgang Reindl et al.
Konstantina Atanasova et al.
The brain-gut axis constitutes the basis for the bidirectional communication between the central nervous system and the gastrointestinal tract driven by neural, hormonal, metabolic, immunological, and microbial signals. Alterations in the g...
Eleftheria Karadima,Triantafyllos Chavakis,Vasileia Ismini Alexaki
Eleftheria Karadima
Metabolic flexibility is key for the function of myeloid cells. Arginine metabolism is integral to the regulation of myeloid cell responses. Nitric oxide (NO) production from arginine is vital for the antimicrobial and pro-inflammatory resp...
Maternal lipids in overweight and obesity: implications for pregnancy outcomes and offspring's body composition [0.03%]
超重和肥胖产妇的血脂对妊娠结局及子代体成分的影响
Marie Albrecht,Anna Worthmann,Jörg Heeren et al.
Marie Albrecht et al.
Overweight and obesity (OWO) are linked to dyslipidemia and low-grade chronic inflammation, which is fueled by lipotoxicity and oxidative stress. In the context of pregnancy, maternal OWO has long been known to negatively impact on pregnanc...
Atsuo Nakamura,Mitsuharu Matsumoto
Atsuo Nakamura
The intestinal epithelium is a rapidly self-renewing tissue; the rapid turnover prevents the invasion of pathogens and harmful components from the intestinal lumen, preventing inflammation and infectious diseases. Intestinal epithelial barr...
Corbett T Berry,Caitlin S Frazee,Patrick J Herman et al.
Corbett T Berry et al.
The management of autoimmune diseases is currently limited by therapies that largely suppress the immune system, often resulting in partial and temporary remissions. Cellular immunotherapies offer a targeted approach by redirecting immune c...
Maternal microchimeric cell trafficking and its biological consequences depend on the onset of inflammation at the feto-maternal interface [0.03%]
胎盘界面炎症发生的时间决定了母体微嵌合细胞的转移及其生物学后果
Emiel Slaats,Bernadette Bramreiter,Kristine J Chua et al.
Emiel Slaats et al.
Microchimerism is defined as the presence of a small population of genetically distinct cells within a host that is derived from another individual. Throughout pregnancy, maternal and fetal cells are known to traffic across the feto-materna...
Galectin-1 and galectin-3 in male reproduction - impact in health and disease [0.03%]
半乳糖凝集素-1和半乳糖凝集素-3在男性生殖系统中的作用：健康与疾病的视角
Monika Fijak,Hiba Hasan,Andreas Meinhardt
Monika Fijak
The formation and differentiation of mature, motile male germ cells, which can fertilize the egg and ensure successful implantation and development of a healthy embryo, are essential functions of the testis and epididymis. Spermatogenesis i...
David Nardo,Emileigh G Maddox,James L Riley
David Nardo
Despite advances in medicine and antimicrobial research, viral infections continue to pose a major threat to human health. While major strides have been made in generating vaccines and small molecules to combat emerging pathogens, new modal...
Clinical relevance of feto-maternal microchimerism in (hematopoietic stem cell) transplantation [0.03%]
孕期胎婴-母体内细胞微嵌合现象在(造血干细胞)移植中的临床意义
Anne Kruchen,Boris Fehse,Ingo Müller
Anne Kruchen
Toleration of a semi-allogeneic fetus in the mother's uterus as well as tolerance after allogeneic hematopoietic stem cell transplantation (HSCT) appear to share some immunologic concepts. The existence of microchimeric cells, and the origi...
Guangfeng Zhao,Yali Hu
Guangfeng Zhao
Intrauterine adhesions (IUA), also known as Asherman's syndrome, arise from damage to the basal layer of the endometrium, frequently caused by intrauterine interventions. This damage leads to nonregenerative healing of endometrium resulting...