NK cells: shielding senescence homeostasis in the decidua during early pregnancy [0.03%]
自然杀伤细胞：早期妊娠期间胎盘中衰老稳态的守护者
Zi-Meng Zheng,Jia-Wei Shi,Li Wang et al.
Zi-Meng Zheng et al.
Decidualization, the transformation of endometrial stromal cells into specialized decidual cells, is essential for embryo implantation and pregnancy maintenance. This process involves immune cell infiltration, especially decidual natural ki...
J Lee Nelson,Nathalie C Lambert
J Lee Nelson
Naturally acquired microchimerism (Mc) is increasingly recognized as an aspect of normal biology. Maternal-fetal bi-directional exchange during pregnancy creates a Mc legacy for the long-term in both individuals. Maternal Mc in her offsprin...
Daniel Pitz Jacobsen,Heidi E Fjeldstad,Maria B Olsen et al.
Daniel Pitz Jacobsen et al.
Cells cross the placenta during pregnancy, resulting in proliferation of semiallogeneic cells in the mother and fetus decades later. This phenomenon, termed microchimerism, is documented across mammalian species, implying an evolutionary be...
Martina A Guggeis,Danielle Mm Harris,Lina Welz et al.
Martina A Guggeis et al.
Understanding the role of the gut microbiota in the pathogenesis of inflammatory bowel diseases (IBD) has been an area of intense research over the past decades. Patients with IBD exhibit alterations in their microbial composition compared ...
Dyslipidemia and female reproductive failures: perspectives on lipid metabolism and endometrial immune dysregulation [0.03%]
血脂异常与女性生殖失败：脂质代谢和子宫内膜免疫失调的视角
Yuan Zhang,Monira Alzahrani,Svetlana Dambaeva et al.
Yuan Zhang et al.
Dyslipidemia is a common metabolic disorder around the world, with a higher incidence in the population of childbearing age and those experiencing infertility. Increasing research has been focused on the impact of dyslipidemia on female rep...
Baruch Rinkevich,Tamar L Goulet
Baruch Rinkevich
Natural chimeras are prevalent in nature (> 10 phyla of protists, plants, invertebrates, and vertebrates), disrupting the conventional believe that genetically homogeneous entities are selected to prevent conflicts within an organism. Chime...
Perturbations of the endometrial immune microenvironment in endometriosis and adenomyosis: their impact on reproduction and pregnancy [0.03%]
子宫内膜异位症和腺肌症中子宫内膜免疫微环境的扰动：对生殖和妊娠的影响
Jialu Shi,Qianhan Xu,Shuyi Yu et al.
Jialu Shi et al.
The impact of endometriosis and adenomyosis on reproduction and pregnancy is significant, with both conditions linked to increased rates of infertility, poor ovarian function in women with endometriosis, and elevated pregnancy complications...
The duality of microchimerism and cancer in parous women: a review and evolutionary perspective [0.03%]
有过孕史的女性中微嵌合体和癌症的二象性：一项综述及演化观点
Cristiano Parmeggiani,Katja Sallinger,H James Cleaves nd et al.
Cristiano Parmeggiani et al.
The transfer of a small number of cells between parent and offspring during pregnancy, commonly referred to as microchimerism, is thought to occur in all human pregnancies. The impact of microchimeric cells on health outcomes in mothers and...
Lessons (to be) learned from liquid biopsies: assessment of circulating cells and cell-free DNA in cancer and pregnancy-acquired microchimerism [0.03%]
从液体活检中(应)吸取的教训：循环细胞和游离DNA在癌症及妊娠获得性微嵌合体中的评估
Lina Bergmann,Ann-Kristin Afflerbach,Tingjie Yuan et al.
Lina Bergmann et al.
Tumors constantly shed cancer cells that are considered the mediators of metastasis via the blood stream. Analysis of circulating cells and circulating cell-free DNA (cfDNA) in liquid biopsies, mostly taken from peripheral blood, have emerg...
Shaping immunity: the influence of the maternal gut bacteria on fetal immune development [0.03%]
塑造免疫系统：母体肠道菌群对胎儿免疫发育的影响
Marijke M Faas,Alexandra M Smink
Marijke M Faas
The development of the fetal immune response is a highly complex process. In the present review, we describe the development of the fetal immune response and the role of the maternal gut bacteria in this process. In contrast to the previous...