Pulmonary sclerosing pneumocytoma with lymph node metastasis and high 18FDG uptake in PET/CT: a rare case report and literature review [0.03%]
肺硬化性肺细胞瘤伴淋巴结转移及PET/CT高18FDG摄取：一例罕见病例报告及文献复习
Jingfeng Xu,Yilei Zhao,Qiuli Wu et al.
Jingfeng Xu et al.
Pulmonary sclerosing pneumocytoma (PSP) was first reported by Liebow and Hubbell (1956). It was initially called pulmonary sclerosing hemangioma (PSH) because it was thought to be derived from endothelial cells with rich vascularity. Howeve...
Consideration of culture in interpersonal psychotherapy practice in Asia: a case study [0.03%]
人际心理治疗在亚洲实践中的文化考量：一项案例研究
Xiaoyi Zhou,Haoyang Zhao,Guoxun Feng et al.
Xiaoyi Zhou et al.
In the realm of precision psychiatry of mood disorders, the evolution of interpersonal psychotherapy (IPT) is gaining momentum, necessitating a personalized approach that also takes into account cultural aspects. This study underscores the ...
Potential relationships between circulating gene expression of ACE2, TLR4, and IL-17 and disease severity and outcome of hospitalized patients with COVID-19 [0.03%]
ACE2、TLR4和IL-17的循环基因表达与COVID-19住院患者的疾病严重程度及预后之间的潜在关系
Marwa A Dahpy,Ragaa H Salama,Abdel-Raheim M A Meki et al.
Marwa A Dahpy et al.
Acute respiratory distress syndrome (ARDS) is a form of progressive hypoxemia that can be brought on by a variety of cardiorespiratory or systemic disorders, such as coronavirus disease 2019 (COVID-19). The binding of a severe acute respira...
Momordicine I induces ER stress and inhibits OSCC by targeting ribosomal proteins [0.03%]
Moslemine I通过靶向核糖体蛋白诱导内质网应激并抑制口腔鳞状细胞癌
Jianlu Kong,Ziyu Zhu,Yijie Hu et al.
Jianlu Kong et al.
Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors worldwide. This necessitates the development of innovative drugs with high efficiency, low toxicity, and good tolerance. Bitter melon extract has been reported t...
Huan Liu,Zemin Li,Yongchang Sun et al.
Huan Liu et al.
Asthma is a complex and chronic inflammatory airway disease associated with the abnormal activation of immune cells. T-cell senescence is linked to immune dysfunction and persistent inflammation, but the relationship between asthma and T-ce...
How do mechanical forces impact macrophages in the processes of mechanosensing and mechanotransduction? [0.03%]
机械力如何影响巨噬细胞的力学传感和力信号转导过程？
Dan Yu,Chenlu Xu,Jinpeng Jiang et al.
Dan Yu et al.
Macrophages are sensitive cells to various external mechanical forces in the environment, such as stretch, shear, and pressure. Mechanical forces can be recognized by mechanical signal receptors on the cell surface, such as cell adhesion mo...
Muhammad Tufail,Caiyun He,Canhua Jiang et al.
Muhammad Tufail et al.
Oral squamous cell carcinoma (OSCC) poses significant challenges in terms of diagnosis and treatment, with high rates of morbidity and mortality. Emerging evidence highlights the critical involvement of Wingless/Int-1 (Wnt) ligands and rece...
Commensal bacteria play a fundamental role in maintaining gut immune homeostasis [0.03%]
共生细菌在维持肠道免疫稳态中起着基础性作用
Shuyu Tu,Yanan Zhang,Li Zhang et al.
Shuyu Tu et al.
The intestinal microbiome, which is a key factor in the maintenance of host gut homeostasis, enhances intestinal mucosal barrier function and immune tolerance (Rooks and Garrett, 2016; Skelly et al., 2019). However, the specific immunomodul...
Wenna Bao,Jinfeng Yao,Haifeng Pan et al.
Wenna Bao et al.
This study used molecular dynamics simulations, B-factor analysis, and saturation mutagenesis screening to enhance the thermal stability of the trans-epoxysuccinate hydrolase (TESH) derived from Pseudomonas koreensis. Eleven mutants that in...
Shuyu capsule improves estrous cycle-dependent depression-like behavior in premenstrual dysphoric disorder (PMDD) mice by increasing GABAergic neuronal activation and downregulating GABAAR δ subunit expression in the dorsal periaqueductal gray (dPAG) region [0.03%]
疏郁颗粒通过上调背侧导水管灰质区GABA能神经元活性及下调GABA受体δ亚基表达缓解经期依赖性抑郁行为研究
Jialing Xu,Kun Liu,Yaru Cui et al.
Jialing Xu et al.
Premenstrual dysphoric disorder (PMDD), a subtype of premenstrual syndrome (PMS), involves physical and emotional symptoms that impact patients' daily lives and productivity. A reliable, side-effect-free clinical intervention is needed. Shu...