Polarizing macrophages derived from human THP-1 cells in vitro: methods and protocols [0.03%]
体外用THP-1细胞衍生的巨噬细胞进行分化的办法和协议
Pengfei Li,Lin Chen,Wei Yuan et al.
Pengfei Li et al.
Macrophages derived from the human THP-1 cell line have been widely used as substitutes for primary macrophages in various macrophage-related studies. However, difficulties still exist in establishing THP-1 macrophage models. This research ...
Selective anastasis induction by bee venom in normal cells: a promising strategy for breast cancer therapy with minimal impact on cell viability [0.03%]
蜂毒有选择性地诱导正常细胞复活：一种对细胞存活影响极小的治疗乳腺癌的新策略
Sinan Tetikoglu,Muharrem Akcan,Ugur Uzuner et al.
Sinan Tetikoglu et al.
Anastasis is a phenomenon described as a cellular escape from ethanol-induced cell death. Although the relevant mechanism has not yet been fully elucidated, anastasis is thought to play a role in drug resistance in cancer cells. To date, th...
Acinetobacter sp. ME1: a multifunctional bacterium for phytoremediation utilizing melanin production, heavy metal tolerance, and plant growth promotion [0.03%]
产黑素、耐重金属和促生的植物修复菌株Acinetobacter sp. ME1
Soo Yeon Lee,Kyung-Suk Cho
Soo Yeon Lee
Microorganisms inhabiting soils contaminated with heavy metals produce melanin, a dark brown pigment, as a survival strategy. In this study, a melanin-producing bacterium, Acinetobacter sp. ME1, with heavy metal tolerance and plant growth-p...
Therapeutic effect of baicalein as an antiparasitic agent against Toxoplasma gondii in vitro and in vivo [0.03%]
黄芩素作为抗寄生虫剂治疗隐孢子虫和弓形虫的体内和体外实验研究
Songrui Wu,Yingmei Lai,Zhong&#x;ao Zhang et al.
Songrui Wu et al.
The most common medications for the treatment of zoonotic toxoplasmosis are pyrimethamine and sulfadiazine, which may cause serious undesirable side effects. Thus, there is an urgent need to develop novel therapeutics. Baicalein (BAI, C15H1...
COMPERA 2.0 risk stratification in patients with severe aortic stenosis: implication for group 2 pulmonary hypertension [0.03%]
严重主动脉瓣狭窄患者中COMPERA 2.0风险分层对第2组肺动脉高压的启示
Zongye Cai,Xinrui Qi,Dao Zhou et al.
Zongye Cai et al.
COMPERA 2.0 risk stratification has been demonstrated to be useful in patients with precapillary pulmonary hypertension (PH). However, its suitability for patients at risk for post-capillary PH or PH associated with left heart disease (PH-L...
From 2D to 3D: transforming malignant bone tumor research with advanced culture models [0.03%]
从2D到3D：利用先进的培养模型转化恶性骨肿瘤研究
Zhengcheng He,Haitao Huang,Jiale Fang et al.
Zhengcheng He et al.
Osteosarcoma (OS), chondrosarcoma (CS), and Ewing sarcoma (ES) represent primary malignant bone tumors and pose significant challenges in oncology research and clinical management. Conventional research methods, such as two-dimensional (2D)...
Food-derived bioactive peptides: health benefits, structure‒activity relationships, and translational prospects [0.03%]
食品源活性多肽：健康效益、构效关系及转化前景
Hongda Chen,Jiabei Sun,Haolie Fang et al.
Hongda Chen et al.
Food-derived bioactive peptides (FBPs), particularly those with ten or fewer amino acid residues and a molecular weight below 1300 Da, have gained increasing attention for their safe, diverse structures and specific biological activities. T...
Alamandine inhibits pathological retinal neovascularization by targeting the MrgD-mediated HIF-1α/VEGF pathway [0.03%]
天门冬氨酸通过靶向MrgD介导的HIF-1α/VEGF通路抑制病理性的视网膜新生血管化
Kun Zhao,Yaping Jiang,Wen Huang et al.
Kun Zhao et al.
Retinopathy of prematurity (ROP) is a vision-threatening disorder that leads to pathological growth of the retinal vasculature due to hypoxia. Here, we investigated the potential effects of alamandine, a novel heptapeptide in the renin-angi...
Pediatric inflammatory bowel disease in mother‒child pairs: clinical risk factors and gut microbiota characteristics [0.03%]
母子对中儿童炎症性肠病的临床危险因素及肠道微生态特征分析
Cunzheng Zhang,Ruqiao Duan,Nini Dai et al.
Cunzheng Zhang et al.
Objectives: The risk factors and role of mother‒child gut microbiota in pediatric inflammatory bowel disease (PIBD) remain unclear. We aimed to explore the clinical risk factors associated with PIBD, analyze the characte...
Roles of the Keap1/Nrf2 pathway and mitophagy in liver diseases [0.03%]
Keap1/Nrf2信号通路及线粒体自噬在肝脏疾病中的作用
Qihui Zhou,Panpan Cen,Zhi Chen et al.
Qihui Zhou et al.
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an intracellular transcription factor that helps protect against oxidative stress in different types of cells under pathological conditions. Mitochondria are vital organelles that functi...