Peng Liu,Xinmiao Xue,Zhixin Zhang et al.
Peng Liu et al.
Tinnitus, a prevalent auditory symptom, can significantly impair quality of life, yet no definitive pharmacological interventions exist despite extensive ongoing research into its pathophysiology and treatments. The advent of biomedical eng...
Microencapsulation and characterization of controlled-release intestinal drugs: a critical review [0.03%]
微球的肠道控释给药研究进展及质量评价关键因素思考
Weiguang Su,Dawei Wang,Siegfried Yeboah et al.
Weiguang Su et al.
Oral administration is associated with high patient adherence, as it is not only the route for primary site absorption of nutrients and peptide drugs but also is important for treating intestinal diseases. However, traditional oral intestin...
Targeting WTAP sensitizes hepatocellular carcinoma to sorafenib by inhibiting the ERK signaling pathway [0.03%]
靶向WTAP通过抑制ERK信号通路使肝细胞癌对索拉非尼敏感
Yu Wu,Guomin Ju,Xueyu Zhou et al.
Yu Wu et al.
Hepatocellular carcinoma (HCC) often requires targeted therapy and immunotherapy due to frequent delayed diagnosis. Sorafenib, the first targeted drug applied to treat HCC, has demonstrated a remarkable therapeutic effect in the clinic. How...
Ectopic expression of structurally similar major royal jelly proteins reveals their distinct functions in Drosophila [0.03%]
结构类似的主王浆蛋白在果蝇中的异位表达揭示了它们不同的功能
Lingqi Yu,Danfeng Wang,Xuanhao Chen et al.
Lingqi Yu et al.
Royal jelly (RJ), secreted by the hypopharyngeal and mandibular glands of young worker bees, is rich in proteins, 80%‒90% of which are major royal jelly proteins (MRJPs). While MRJPs from RJ have been shown to exhibit specific biological f...
Roles of try and amy in feeding, digestion, growth, and development of the Japanese medaka (Oryzias latipes): insight from a comparative gene knockout study [0.03%]
斑马鱼与日本河川鳉同源基因try和amy在摄食、消化、生长及发育中作用的比较基因敲除研究
Xiaodan Jia,Shulin Tang,Hexiong Feng et al.
Xiaodan Jia et al.
Digestive enzymes of fish are critical to food digestion at the larval stage, but convincing evidence proving the function and necessity of the associated digestive enzymes remains lacking. In this study, we generated the trypsin (try) gene...
Genomic insights into the diversity of rice cultivars developed in Heilongjiang Province, China [0.03%]
中国黑龙江省栽培稻品种多样性的基因组学见解
Yuhan Zhou,Naixin Liu,Jiaqi Yang et al.
Yuhan Zhou et al.
Amid the rapid increase of the global population and the quest for sustainable agriculture, the need for enhanced rice breeding strategies has become increasingly pronounced, particularly in Heilongjiang, China's foremost rice-producing pro...
Integrative combination of gas‒liquid-phase plasma mutagenesis and high-throughput screening to enhance eicosapentaenoic acid production by Schizochytrium sp [0.03%]
结合气液相等离子体诱变和高通量筛选的整合方法增强Schizochytrium sp中二十碳五烯酸的生成能力
Chao Yu,Jialin Zhu,Jinyong Wu et al.
Chao Yu et al.
Dietary consumption of eicosapentaenoic acid (EPA) offers diverse health benefits, such as the regulation of blood triglycerides and the prevention of cardiovascular diseases. EPA is naturally synthesized by Schizochytrium sp.; however, its...
A novel bacterial strain for the removal of ammonia nitrogen from wastewater: Pseudomonas oleovorans QS-7 [0.03%]
一株新型氨氮去除菌株的分离鉴定：QS-7菌株
Hao Qiu,Min Liao,Xiaomei Xie et al.
Hao Qiu et al.
Excessive ammonia nitrogen has been demonstrated to cause a serious hazard to water environments. Bacteria performing simultaneous nitrification and denitrification (SND) can be effective biological instruments to remove ammonia nitrogen co...
Recent research advances in the biological function and molecular mechanism of methylmalonic acid [0.03%]
甲基丙二酸生物功能及分子机制的研究进展
Zi&#x;ang Wang,Wenhui Cheng,Teng Wang et al.
Zi&#x;ang Wang et al.
The abnormal accumulation of methylmalonic acid (MMA), the leading cause of methylmalonic acidemia, can cause irreversible damage to the brain, kidney, and cardiovascular system. In addition, the accumulation of MMA in the blood has recentl...
Roles of Wnt signaling pathway in cementum formation, cementum regeneration, and cementocyte function [0.03%]
Wnt信号通路在牙骨质形成、牙骨质再生及牙骨质细胞功能中的作用
Tiancheng Li,Xinyi Zeng,Shuxian Yang et al.
Tiancheng Li et al.
Cementum, a mineralized connective tissue that covers the tooth root, is crucial in protecting the root from resorption, maintaining occlusal relationships, and supporting tooth function. Cementocytes are embedded within the cementum matrix...