CXCL16 promotes proliferation of head and neck squamous cell carcinoma by regulating GPX1-mediated antioxidant levels [0.03%]
CXCL16通过调节GPX1介导的抗氧化剂水平促进头颈部鳞状细胞癌增殖
Ru He,Hongyi Jiang,Chengchi Zhang et al.
Ru He et al.
Numerous studies have demonstrated that the high expression of CXC motif chemokine ligand 16 (CXCL16) in cancer correlates with poor prognosis, as well as tumor cell proliferation, migration, and invasion. While CXCL16 can serve as a tumor ...
Chronic exposure to hexavalent chromium induces esophageal tumorigenesis via activating the Notch signaling pathway [0.03%]
六价铬的慢性暴露通过激活Notch信号通路诱导食管肿瘤发生
Yilin Zhu,Fanrong Liu,Lei Liu et al.
Yilin Zhu et al.
Hexavalent chromium Cr(VI), as a well-established carcinogen, contributes to tumorigenesis for many human cancers, especially respiratory and digestive tumors. However, the potential function and relevant mechanism of Cr(VI) on the initiati...
ATP-binding cassette (ABC) transporters: structures and roles in bacterial pathogenesis [0.03%]
ATP结合盒式（ABC）转运蛋白：结构及其在细菌致病性中的作用
Shu Sian How,Sheila Nathan,Su Datt Lam et al.
Shu Sian How et al.
Adenosine triphosphate (ATP)-binding cassette (ABC) transporter systems are divided into importers and exporters that facilitate the movement of diverse substrate molecules across the lipid bilayer, against the concentration gradient. These...
Repetitive transcranial magnetic stimulation combined with imaginal exposure therapy for adolescents with acute stress disorder: case report [0.03%]
重复经颅磁刺激联合想象力暴露疗法治疗急性应激障碍青少年患者：个案报告
Miaomiao Zhao,Ying Li,Haoyang Zhao et al.
Miaomiao Zhao et al.
Acute stress disorder (ASD) is a transient psychiatric disorder that may arise subsequent to abrupt, extreme trauma exposure, and serves as a reliable indicator for the subsequent development of posttraumatic stress disorder (PTSD) (Bryant,...
Aberrant network topological structure of sensorimotor superficial white-matter system in major depressive disorder [0.03%]
重度抑郁症患者感觉运动皮层浅白质系统异常的网络拓扑结构研究
Peng Wang,Yanling Bai,Yang Xiao et al.
Peng Wang et al.
White-matter tracts play a pivotal role in transmitting sensory and motor information, facilitating interhemispheric communication and integrating different brain regions. Meanwhile, sensorimotor disturbance is a common symptom in patients ...
Clinical efficacy and safety of vortioxetine as an adjuvant drug for patients with bipolar depression [0.03%]
伏硫西汀联用治疗双相抑郁患者的临床疗效及安全性研究
Chunxiao Dai,Yaoyang Fu,Xuanwei Li et al.
Chunxiao Dai et al.
Objectives: Whether vortioxetine has a utility as an adjuvant drug in the treatment of bipolar depression remains controversial. This study aimed to validate the efficacy and safety of vortioxetine in bipolar depression. ...
Randomized Controlled Trial
Journal of Zhejiang University. Science. B. 2025 Jan 15;26(1):26-38. DOI:10.1631/jzus.B2400470 2025
Residual hyperglycemia after successful treatment of a patient with severe copper sulfate poisoning [0.03%]
重症硫酸铜中毒患者经成功救治后的残余高血糖现象报告
Ting Li,Yuan-Qiang Lu
Ting Li
Copper sulfate is a frequently used copper compound in laboratory settings, with instances of poisoning being uncommon. A study conducted by the American Association of Poison Control Centers' National Poison Data System found that only 140...
Autophagy receptor-inspired chimeras: a novel approach to facilitate the removal of protein aggregates and organelle by autophagy degradation [0.03%]
受自噬受体启发的嵌合体：通过自噬降解促进蛋白质聚集物和细胞器去除的新方法
Liwen Wang,Huimei Liu,Lanfang Li
Liwen Wang
Neurodegenerative diseases (NDDs), mainly including Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), and Alzheimer's disease (AD), are sporadic and rare genetic disorders of the central nervous system. A key feature of these ...
Olig2+ single-colony-derived cranial bone-marrow mesenchymal stem cells achieve improved regeneration in a cuprizone-induced demyelination mouse model [0.03%]
Olig2阳性单克隆颅骨骨髓间充质干细胞在杯扎酮致脱髓鞘小鼠模型中实现更有效的再生
Deqing Peng,Ruijie Lu,Leyao Lü et al.
Deqing Peng et al.
Oligodendrocytes are the myelinating cells of the central nervous system. Brain injury and neurodegenerative disease often lead to oligodendrocyte death and subsequent demyelination-related pathological changes, resulting in neurological de...
Co-culture of natural killer cells and tumor spheroids on a heterogeneous multilayer paper stack [0.03%]
基于异质多层纸张的天然杀伤细胞与肿瘤球形瘤体共培养模型研究
Yuanyuan Xie,Xiaoyan Yang,Rong Pan et al.
Yuanyuan Xie et al.
Multilayer paper-based cell culture, as an in vitro three-dimensional (3D) cell culture method, has been frequently used to research drug bioavailability, therapeutic efficacy, and dose-limiting toxicity in malignant tumors. This paper prop...