Pig meniscus single-cell sequencing reveals highly active red zone chondrocyte populations involved in stemness maintenance and vascularization development [0.03%]
猪半月板单细胞测序揭示参与维持干细胞活性和血管发育的红色区域软骨细胞群
Monika Mankowska,Monika Stefanska,Anna Maria Mleczko et al.
Monika Mankowska et al.
Meniscus injuries are widespread and the available treatments do not offer enough healing potential. Here, we provide critical support for using pigs as a biological model for meniscal degeneration and the development of cutting-edge therap...
Qianhui Li,Hongye Lu,Mengyuan Zhang et al.
Qianhui Li et al.
Peri-implant diseases are characterized by the resorption of hard tissue and the inflammation of soft tissue. Epigenetics refers to alterations in the expression of genes that are not encoded in the DNA sequence, influencing diverse physiol...
EGCG as a therapeutic agent: a systematic review of recent advances and challenges in nanocarrier strategies [0.03%]
绿茶儿茶素 EGCG 作为治疗剂：纳米递送载体策略的近期进展和挑战系统的回顾
Chee Ning Wong,Yang Mooi Lim,Kai Bin Liew et al.
Chee Ning Wong et al.
Epigallocatechin-3-gallate (EGCG), a bioactive polyphenol abundant in green tea, has garnered significant attention for its diverse therapeutic applications, ranging from antioxidant and anti-inflammatory effects to potential anticancer pro...
Small fish making a big difference: beloved star of environmental toxicology research in the current era [0.03%]
微小鱼儿大作为——当前环境毒理学研究的宠儿
Yang Jiang,Zhen Su,Jing Zheng et al.
Yang Jiang et al.
The zebrafish has emerged as a powerful model organism in life science owing to its remarkable biological characteristics and wide-ranging applications. This review provides a comprehensive overview of the recent advancements in research on...
Seeing the macro in the micro: a diffusion model-based approach for style transfer in cellular images [0.03%]
微观见宏观：细胞图像中的基于扩散模型的风格迁移方法
Jiayi Cai,Yong He,Feng Liu et al.
Jiayi Cai et al.
The internal structures of cells as the basic units of life are a major wonder of the microscopic world. Cellular images provide an intriguing window to help explore and understand the composition and function of these structures. Scientifi...
Single-cell transcriptome analysis reveals abnormal angiogenesis and placentation by loss of imprinted glutaminyl-peptide cyclotransferase [0.03%]
单细胞转录组分析揭示了谷氨酰肽环转移酶印迹丢失导致血管生成和胎盘发育异常
Jing Guo,Jihong Zheng,Ruixia Li et al.
Jing Guo et al.
Imprinted genes play a key role in regulating mammalian placental and embryonic development. Here, we generated glutaminyl-peptide cyclotransferase-knockout (Qpct-/-) mice utilizing the clustered regularly interspaced short palindromic repe...
Fibroblast growth factors and endometrial decidualization: models, mechanisms, and related pathologies [0.03%]
成纤维细胞生长因子与子宫内膜蜕膜化：模型、机制及相关病理学
Xueni Zhang,Yidi Mo,Chunbin Lu et al.
Xueni Zhang et al.
The onset of pregnancy is marked by the formation of a zygote, while the culmination of gestation is manifested by the delivery of a fetus. Meanwhile, a successful pregnancy entails a meticulously coordinated sequence of events from embryo ...
Potential role of FNDC5 in exercise-induced improvement of cognitive function [0.03%]
FNDC5在运动改善认知功能中的潜在作用
Ruobing Zhao,Xuchang Zhou,Dongxue Wang et al.
Ruobing Zhao et al.
Cognitive dysfunction often occurs in Alzheimer's disease, Parkinson's disease, cerebrovascular disease, or other neurodegenerative diseases, and can significantly impact the life quality of patients and create serious social, psychological...
New characteristics of cancer immunotherapy: trends in viral tumor immunotherapy with influenza virus-based approaches [0.03%]
癌症免疫治疗的新特征：基于流感病毒的肿瘤免疫治疗发展趋势
Shiyao Hu,Yiqi Cai,Yong Shen et al.
Shiyao Hu et al.
Immunomodulatory cancer therapy is witnessing the rise of viral immunotherapy. The oncolytic influenza A virus, although promising in preclinical investigations, remains to be implemented in clinical practice. Recent progress in genetic eng...
Tolulope Joshua Ashaolu
Tolulope Joshua Ashaolu
The cosmetic sector is a multibillion-dollar industry that requires constant attention being paid to innovative product development and engagement. Notably, its market value is projected to exceed 750 billion U.S. dollars by 2025, and it is...