Late-onset intracranial adenocarcinoma arising from a germ cell tumor 25 years after initial diagnosis [0.03%]
首次诊断25年后晚发性颅内生殖细胞肿瘤来源的腺癌
Yuri Yamagiwa,Masashi Nomura,Hirokazu Takami et al.
Yuri Yamagiwa et al.
A teratoma with somatic-type malignancy is a rare subtype of germ cell tumor (GCT) characterized by the presence of a histologically distinct component resembling a somatic cancer within a teratoma feature. To date, only 14 cases have been ...
A rare case of supratentorial ependymosarcoma harboring ZFTA::RELA fusion [0.03%]
一例罕见的ZFTA/RELA融合阳性的幕上ependymosarcoma
Yuji Matsumoto,Yasuki Suruga,Kaishi Satomi et al.
Yuji Matsumoto et al.
Ependymosarcoma is an exceedingly rare variant of ependymoma characterized by a mixture of ependymomatous and sarcomatous components. We report a case of supratentorial ependymosarcoma harboring a ZFTA::RELA fusion in a 10-year-old girl. Hi...
Histopathological evaluation of dopamine receptor D2 expression in symptomatic gonadotroph pituitary neuroendocrine tumors: a case series including a rare metastatic case responsive to a dopamine agonist [0.03%]
多巴胺受体D2在有症状的垂体神经内分泌肿瘤中的组化表达：包括罕见转移性垂体促性腺激素细胞肿瘤对多巴胺激动剂治疗反应的良好病例报告
Ken Uekawa,Naoki Shinojima,Takahiro Yamamoto et al.
Ken Uekawa et al.
Functioning gonadotroph pituitary neuroendocrine tumors (Gn-PitNETs) cause ovarian hyperstimulation. We report Gn-PitNETs, including a distant metastasis case responsive to a dopamine agonist (DA), cabergoline. A 10-year-old girl presented ...
Primary sellar glomus tumor with BRAF K601E mutation: an aggressive tumor of uncertain malignant potential [0.03%]
带有BRAF K601E突变的垂体顶泌性血管活门瘤：一种潜在恶性的具有侵袭性的肿瘤
Bin Mi,Benjamin Ka Seng Thong,Li Jiang et al.
Bin Mi et al.
Glomus tumor (GT) is a mesenchymal neoplasm composed of modified perivascular cells exhibiting smooth muscle-like features, resembling those of the normal glomus body. The lesions often occur in areas rich in glomus vascularis, most of whic...
Gyriform infiltration indicates tumor invasion burden of isocitrate dehydrogenase 1/2-wildtype gliomas [0.03%]
gyriform浸润提示缺琥珀酸脱氢酶1/2型胶质瘤的肿瘤侵袭负荷
Hideyuki Arita,Kentaro Hirai,Mio Sakai et al.
Hideyuki Arita et al.
Few robust radiological markers have been identified for predicting the molecular status of gliomas. Recently, gyriform infiltration (GI) has been identified as an imaging biomarker for molecular glioblastoma (mGBM). This study aimed to val...
Reappraisal of novel molecular parameters for meningioma grading by cIMPACT-NOW update 8 proposals [0.03%]
cIMPACT-NOW更新版8提案对脑膜瘤分级新分子参数的再评估
Kenta Masui,Asuka Komori,Shuhei Morita et al.
Kenta Masui et al.
Ataxin-2 as a candidate blood biomarker for estimating disease status in cases of suspected glioblastoma recurrence [0.03%]
共济蛋白2作为怀疑胶质母细胞瘤复发病例的疾病评估候选血液生物标志物
Farida Garaeva,Riho Nakajima,Sho Tamai et al.
Farida Garaeva et al.
Differentiating pseudoprogression (PsP) from recurrence in cases of glioblastoma (GBM) after chemoradiotherapy is challenging, with neuroimaging as the only non-invasive method. In this study, we aimed to identify a blood biomarker for prec...
Diffuse midline glioma, H3K27-altered: a rare presentation with gliomatosis cerebri growth pattern and progression toward midline [0.03%]
H3K27改变的弥漫性中线胶质瘤伴脑干受累及全脑生长模式及其发展过程中的中线转移的一例罕见病例报告
Masahiro Uchimura,Asuka Araki,Hirotake Eda et al.
Masahiro Uchimura et al.
A limited number of cases involving non-midline lesions have been documented in diffuse midline glioma (DMG), H3K27-altered, for which a definitive classification has yet to be developed. Additionally, no studies have investigated the tempo...
Meningioma with trabecular architecture: a harbinger of BAP1 deficiency [0.03%]
具有 trabecular 结构的脑膜瘤：BAP1 缺陷的前兆
Noriko Okuno,Takahiro Tomita,Takuya Akai et al.
Noriko Okuno et al.
BRCA (BReast CAncer gene)-associated protein 1 (BAP1) is a tumor suppressor protein encoded by the BAP1 gene. BAP1 mutations and the loss of BAP1 expression on immunohistochemistry are poor prognostic factors for meningiomas. These mutation...
Emergence of NEC features in corticotroph PitNETs: primary tumor, radiation-induced transformation, or metastasis? [0.03%]
垂体PitNETs中NEC特征的出现：原发肿瘤、放射诱导转化还是转移？
Naoko Inoshita,Hiroshi Nishioka,Noriaki Fukuhara et al.
Naoko Inoshita et al.
Pituitary neuroendocrine tumors (PitNETs) are generally benign, but a small subset may demonstrate aggressive behavior or undergo malignant transformation. Neuroendocrine carcinoma (NEC), defined as a high-grade, poorly differentiated neuro...